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Researchers from the ibs.GRANADA create a marker for the early detection of kidney failure

Researchers from the ibs.GRANADA
ibs.GRANADA  ·  News
April 16th 2014

A multidisciplinary team made up of professionals from the Granada Inter-Center Nephrology Unit and the Health Sciences Department of the University of Jaén has been distinguished at the 42nd congress of the Andalusian Society of Nephrology for a work on the use of early detection biomarkers of renal failure in patients admitted to the Intensive Care Unit after cardiac intervention.

This group of nephropathology, belonging to the Biosanitary Research Institute of Granada, has won first prize for an oral presentation entitled "Role of aminopeptidases in urine as early and predictive markers of acute kidney injury in patients undergoing cardiac surgery" and whose authors were nephrologists Javier de Teresa and Antonio Osuna, intensive care specialist Francisco Manzano, and professor of the Department of Physiology, Rosemary Wangensteen.

This work tries to demonstrate the usefulness of a new biomarker developed by the research team of the Intercentre Nephrology Management Unit. In this way, 110 patients have been studied in one year and since it has been proven that urine elimination increases at 12 hours in patients who will develop this failure, this early marker offers greater sensitivity and specificity to differentiate patients that they will not manifest it, being able to predict in these twelve hours the degree of renal dysfunction that will occur 48 hours later.

At this Andalusian congress, the award was also given to the first poster produced by nephrologists and endocrinologists from Granada, entitled "First step in nutritional assessment in a hemodialysis unit. Malnutrition Inflammation Scale (MIS)" by Dolores Prados, Celia Burbano, María Ramírez, María Luisa Fernández, Limber Iván Rojas, Álvaro Ossorio, and Antonio Osuna.

This work concludes that the risk factors for presenting malnutrition such as age, diabetes, time on dialysis as well as the presence of comorbidity. And that early detection of malnutrition in hemodialysis can improve quality of life and reduce morbidity and mortality


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