NEUROCIENCIAS CLÍNICAS
Grupos de investigación IBS-MP-06
NEUROCIENCIAS CLÍNICAS
Grupo de investigación básica, clínica y traslacional sobre las enfermedades neurológicas, con especial dedicación a las enfermedades neurodegerativas, además de otras áreas como epilepsia y enfermedades cerebrovasculares. Dentro de las enfermedades neurodegenerativas sus líneas principales abordan la enfermedad de Parkinson y otros trastornos del movimiento (genética; mecanismos de neurodegeneración y neuroprotección; biomarcadores y biología molecular; tratamiento quirúrgico y otras terapias mediante dispositivos; disfunción precoz del sistema nervioso autónomo, monitorización de ritmos circadianos, análisis de la marcha, ensayos clínicos) y la enfermedad de Alzheimer y otras demencias (instrumentos de evaluación cognitiva; biomarcadores por imagen funcional y LCR; psicobiología del aprendizaje y la memoria; cognición y envejecimiento).
Lineas de investigación
- Enfermedad de Alzheimer y otras demencias.
- Enfermedad de Parkinson y otros trastornos del movimiento.
- Enfermedades cerebrovasculares
- Epilepsia.
Palabras clave
Biología Molecular. Biomarcadores. Enfermedad de Alzheimer. Enfermedad de Parkinson. Epilepsia. Demencias. Genética. Ictus. Neurocirugía. Neurología. Neuropsicología. Trastornos del Movimiento.
| Miembro |
|---|
| BARRERO HERNÁNDEZ, FRANCISCO JAVIER |
| SÁNCHEZ GONZÁLEZ, CRISTINA |
| DURÁN OGALLA, RAQUEL |
| HORCAJADAS ALMANSA, ANGEL |
| OLIVARES GRANADOS, GONZALO |
| SÁEZ MORENO, JOSÉ ANTONIO |
| MADRID NAVARRO, CARLOS JAVIER |
| JOUMA KATATI, MAJED |
| RODRÍGUEZ FERRER, JOSÉ MANUEL |
| VIVES MONTERO, FRANCISCO |
| GALLO TORRE, MILAGROS |
| PEINADO HERREROS, JOSÉ MARÍA |
| BANDRÉS CIGA, SARA |
| LLOPIS GONZÁLEZ, JUAN |
| RUIZ GIMÉNEZ, JESUS ANTONIO |
| MINGUEZ CASTELLANOS, ADOLFO |
| MEMBRILLA MESA, MIGUEL DAVID |
| ESCAMILLA SEVILLA, FRANCISCO |
Fernández JG, Sánchez-González C, Bettmer J, Llopis J, Jakubowski N, Panne U, Montes-Bayón M
Quantitative assessment of the metabolic products of iron oxide nanoparticles to be used as iron supplements in cell cultures.
Analytica chimica acta, 2018; 1039; 24-30
FI: 5.123; Q1 / D1
Pinel-Ríos J, Madrid-Navarro CJ, Pérez-Navarro MJ, Campos-Arillo V, Mínguez-Castellanos A, Escamilla-Sevilla F
Inflammatory bowel disease and risk of Parkinson's disease.
Parkinsonism & related disorders, 2018; 57; 78-79
FI: 4.721; Q1 / D2
Kia DA, Sabir MS, Ahmed S, Trinh J, Bandres-Ciga S, International Parkinson's Disease Genomics Consortium
LRP10 in α-synucleinopathies.
The Lancet. Neurology, 2018; 17(12); 1032
FI: 27.144; Q1 / D1
Lopez Zuñiga MA, Andreo Jimenez J, Barrero Hernández FJ
When a stroke is not a stroke
EMERGENCIAS, 2018; 30; 136-137
FI: 3.608; Q1 / D1
Giampieri F, Quiles JL, Orantes-Bermejo FJ, Gasparrini M, Forbes-Hernandez TY, Sánchez-González C, Llopis J, Rivas-García L, Afrin S, Varela-López A, Cianciosi D, Reboredo-Rodriguez P, Fernández-Piñar CT, Iglesias RC, Ruiz R, Aparicio S, Crespo J, Dzul Lopez L, Xiao J, Battino M
Are by-products from beeswax recycling process a new promising source of bioactive compounds with biomedical properties?
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2018; 112; 126-133
FI: 3.977; Q1 / D1
Lopez-Chaves C, Soto-Alvaredo J, Montes-Bayon M, Bettmer J, Llopis J, Sanchez-Gonzalez C
Gold nanoparticles: Distribution, bioaccumulation and toxicity. In vitro and in vivo studies.
Nanomedicine : nanotechnology, biology, and medicine, 2018; 14(1); 1-12
FI: 6.5; Q1 / D1
López P, Castro A, Flórez M, Miranda K, Aranda P, Sánchez-González C, Llopis J, Arredondo M
miR-155 and miR-122 Expression of Spermatozoa in Obese Subjects.
Frontiers in genetics, 2018; 9; 175
FI: 4.151; Q1 / D3
Blauwendraat C, Bandrés-Ciga S, Singleton AB
Predicting progression in patients with Parkinson's disease.
The Lancet. Neurology, 2017; 16(11); 860-862
FI: 27.144; Q1 / D1
Morillas E, Gómez-Chacón B, Gallo M
Flavor and object recognition memory impairment induced by excitotoxic lesions of the perirhinal cortex.
Neurobiology of learning and memory, 2017; 144; 230-234
FI: 3.244; Q1 / D3
Bandrés-Ciga S, Ruz C, Barrero FJ, Escamilla-Sevilla F, Pelegrina J, Vives F, Duran R
Structural genomic variations and Parkinson's disease.
Minerva medica, 2017; 108(5); 438-447
FI: 2.863; Q1 / D3
Bandres-Ciga S, Cookson MR
Alpha-synuclein triggers T-cell response. Is Parkinson's disease an autoimmune disorder?
Movement disorders : official journal of the Movement Disorder Society, 2017; 32(9); 1327
FI: 7.072; Q1 / D1
Banegas I, Prieto I, Segarra AB, Vives F, de Gasparo M, Duran R, de Dios Luna J, Ramírez-Sánchez M
Bilateral distribution of enkephalinase activity in the medial prefrontal cortex differs between WKY and SHR rats unilaterally lesioned with 6-hydroxydopamine.
Progress in neuro-psychopharmacology & biological psychiatry, 2017; 75; 213-218
FI: 4.185; Q1 / D2
Sanchez-Gonzalez C, Moreno L, Lopez-Chaves C, Nebot E, Pietschmann P, Rodriguez-Nogales A, Galvez J, Montes-Bayon M, Sanz-Medel A, Llopis J
Effect of vanadium on calcium homeostasis, osteopontin mRNA expression, and bone microarchitecture in diabetic rats.
Metallomics : integrated biometal science, 2017; 9(3); 258-267
FI: 4.069; Q1 / D3
Bandrés-Ciga S, Price TR, Barrero FJ, Escamilla-Sevilla F, Pelegrina J, Arepalli S, Hernández D, Gutiérrez B, Cervilla J, Rivera M, Rivera A, Ding JH, Vives F, Nalls M, Singleton A, Durán R
Genome-wide assessment of Parkinson's disease in a Southern Spanish population.
Neurobiology of aging, 2016; 45; 213.e3-213.e9
FI: 5.117; Q1 / D1
Martín IT, Ávila Rdel M, Herrera MZ, Arregui G, Osorio-Ceballos JL, Rojas ES, Almansa ÁH, Arrebola JP, Rull JP, Hernández JE, Ramírez EL
Role of radiosurgery in the management of glomus tumors.
Head & neck, 2016; 38 Suppl 1; E798-804
FI: 3.376; Q1 / D1
Bandrés-Ciga S, Mencacci NE, Durán R, Barrero FJ, Escamilla-Sevilla F, Morgan S, Hehir J, Vives F, Hardy J, Pittman AM
Analysis of the genetic variability in Parkinson's disease from Southern Spain.
Neurobiology of aging, 2016; 37; 210.e1-210.e5
FI: 5.117; Q1 / D1
Antonio-Rubio I, Madrid-Navarro CJ, Salazar-López E, Pérez-Navarro MJ, Sáez-Zea C, Gómez-Milán E, Mínguez-Castellanos A, Escamilla-Sevilla F
Abnormal thermography in Parkinson's disease.
Parkinsonism & related disorders, 2015; 21(8); 852-7
FI: 3.794; Q1 / D2
Gómez-Garre P, Huertas-Fernández I, Cáceres-Redondo MT, Alonso-Canovas A, Bernal-Bernal I, Blanco-Ollero A, Bonilla-Toribio M, Burguera JA, Carballo M, Carrillo F, José Catalán-Alonso M, Escamilla-Sevilla F, Espinosa-Rosso R, Carmen Fernández-Moreno M, García-Caldentey J, García-Moreno JM, Giacometti-Silveira S, Gutiérrez-García J, Jesús-Maestre S, López-Valdés E, Martínez-Castrillo JC, Medialdea-Natera MP, Méndez-Lucena C, Mínguez-Castellanos A, Angel Moya M, Ochoa-Sepulveda JJ, Ojea T, Rodríguez N, Rubio-Agusti I, Sillero-Sánchez M, Del Val J, Vargas-González L, Mir P
Lack of validation of variants associated with cervical dystonia risk: a GWAS replication study.
Movement disorders : official journal of the Movement Disorder Society, 2014; 29(14); 1825-8
FI: 5.68; Q1 / D1
Gómez-Garre P, Huertas-Fernández I, Cáceres-Redondo MT, Alonso-Canovas A, Bernal-Bernal I, Blanco-Ollero A, Bonilla-Toribio M, Burguera JA, Carballo M, Carrillo F, Catalán-Alonso MJ, Escamilla-Sevilla F, Espinosa-Rosso R, Fernández-Moreno MC, García-Caldentey J, García-Moreno JM, García-Ruiz PJ, Giacometti-Silveira S, Gutiérrez-García J, Jesús S, López-Valdés E, Martínez-Castrillo JC, Martínez-Torres I, Medialdea-Natera MP, Méndez-Lucena C, Mínguez-Castellanos A, Moya M, Ochoa-Sepulveda JJ, Ojea T, Rodríguez N, Sillero-Sánchez M, Vargas-González L, Mir P
BDNF Val66Met polymorphism in primary adult-onset dystonia: a case-control study and meta-analysis.
Movement disorders : official journal of the Movement Disorder Society, 2014; 29(8); 1083-6
FI: 5.68; Q1 / D1
Olivares A, Ruiz-Garcia G, Olivares G, Górriz JM, Ramirez J
Automatic determination of validity of input data used in ellipsoid fitting MARG calibration algorithms.
Sensors (Basel, Switzerland), 2013; 13(9); 11797-817
FI: 2.048; Q1 / D2
Benito-León J, Cubo E, Coronell C, ANIMO Study Group
Impact of apathy on health-related quality of life in recently diagnosed Parkinson's disease: the ANIMO study.
Movement disorders : official journal of the Movement Disorder Society, 2012; 27(2); 211-8
FI: 4.558; Q1 / D2
Sáez-Zea C, Escamilla Sevilla F, Pérez Navarro MJ, Ortega Moreno A, Carnero Pardo C, Mínguez Castellanos A.
Screening for cognitive Impairment and dementia in Parkinson´s disease using multivariate predictive models
MOVEMENT DISORDERS, 2012; 27;
FI: 4.558; Q1 / D2
Sáez-Zea C, Escamilla Sevilla F, Pérez Navarro MJ, Ortega Moreno A, Carnero Pardo C, Mínguez Castellanos A.
Olfactory dysfunction is associated with cognitive Impairment in Parkinson´s disease.
MOVEMENT DISORDERS, 2012; 27;
FI: 4.558; Q1 / D2
Olivares A, Ramírez J, Górriz JM, Olivares G, Damas M
Detection of (in)activity periods in human body motion using inertial sensors: a comparative study.
Sensors (Basel, Switzerland), 2012; 12(5); 5791-814
FI: 1.953; Q1 / D2
Becerra JL, Ojeda J, Corredera E, Ruiz Giménez J
Review of therapeutic options for adjuvant treatment of focal seizures in epilepsy: focus on lacosamide.
CNS drugs, 2011; 25 Suppl 1; 3-16
FI: 4.795; Q1 / D1
Valldeoriola F, Coronell C, Pont C, Buongiorno MT, Cámara A, Gaig C, Compta Y, ADHESON Study Group
Socio-demographic and clinical factors influencing the adherence to treatment in Parkinson's disease: the ADHESON study.
European journal of neurology, 2011; 18(7); 980-7
FI: 3.692; Q1 / D2
Wächter T, Mínguez-Castellanos A, Valldeoriola F, Herzog J, Stoevelaar H
A tool to improve pre-selection for deep brain stimulation in patients with Parkinson's disease.
Journal of neurology, 2011; 258(4); 641-6
FI: 3.473; Q1 / D3
Romani R, Lehto H, Laakso A, Horcajadas A, Kivisaari R, von und zu Fraunberg M, Niemelä M, Rinne J, Hernesniemi J
Microsurgery for previously coiled aneurysms: experience with 81 patients.
Neurosurgery, 2011; 68(1); 140-53; discussion 153-4
FI: 2.785; Q1 / D2
Santiago-Ramajo S, Katati MJ, Pérez-García M, Arjona-Moron V
Evaluating the recovery of cognitive impairment in subarachnoid hemorrhage taking into consideration the practice effects.
Neurosurgery, 2010; 67(6); 1497-504; discussion 1504
FI: 3.298; Q1 / D1
Escamilla-Sevilla F, Minguez-Castellanos A
Deep-brain stimulation for Parkinson's disease.
The New England journal of medicine, 2010; 363(10); 987; author reply 988
FI: 53.486; Q1 / D1
Valldeoriola F, Regidor I, Mínguez-Castellanos A, Lezcano E, García-Ruiz P, Rojo A, Salvador A, Castro A, Grandas F, Kulisevsky J, Martí MJ, Martínez-Martín P, Relova L, Rumià J, Cámara A, Burguera JA, Linazasoro G, de Val JL, Obeso J, Rodríguez-Oroz MC, Tolosa E, Grupo ESpañol para el EStudio de la EStimulación PALidal en la DIStonía
Efficacy and safety of pallidal stimulation in primary dystonia: results of the Spanish multicentric study.
Journal of neurology, neurosurgery, and psychiatry, 2010; 81(1); 65-9
FI: 4.791; Q1 / D1
Rubio de la Torre E, Luzón-Toro B, Forte-Lago I, Minguez-Castellanos A, Ferrer I, Hilfiker S
Combined kinase inhibition modulates parkin inactivation.
Human molecular genetics, 2009; 18(5); 809-23
FI: 7.386; Q1 / D1
Martinez-Martin P, Tolosa E, Hernandez B, Badia X, ValidQUICK Study Group
Validation of the "QUICK" questionnaire--a tool for diagnosis of "wearing-off" in patients with Parkinson's disease.
Movement disorders : official journal of the Movement Disorder Society, 2008; 23(6); 830-6
FI: 3.898; Q1 / D2
Mínguez-Castellanos A, Escamilla-Sevilla F, Hotton GR, Toledo-Aral JJ, Ortega-Moreno A, Méndez-Ferrer S, Martín-Linares JM, Katati MJ, Mir P, Villadiego J, Meersmans M, Pérez-García M, Brooks DJ, Arjona V, López-Barneo J
Carotid body autotransplantation in Parkinson disease: a clinical and positron emission tomography study.
Journal of neurology, neurosurgery, and psychiatry, 2007; 78(8); 825-31
FI: 3.857; Q1 / D1
Minguez-Castellanos A, Chamorro CE, Escamilla-Sevilla F, Ortega-Moreno A, Rebollo AC, Gomez-Rio M, Concha A, Munoz DG
Do alpha-synuclein aggregates in autonomic plexuses predate Lewy body disorders?: a cohort study.
Neurology, 2007; 68(23); 2012-8
FI: 6.014; Q1 / D1
Katati MJ, Santiago-Ramajo S, Pérez-García M, Meersmans-Sánchez Jofré M, Vilar-Lopez R, Coín-Mejias MA, Caracuel-Romero A, Arjona-Moron V
Description of quality of life and its predictors in patients with aneurysmal subarachnoid hemorrhage.
Cerebrovascular diseases (Basel, Switzerland), 2007; 24(1); 66-73
FI: 2.534; Q1 / D3
Martí-Fàbregas J, Bravo Y, Cocho D, Martí-Vilalta JL, Díaz-Manera J, San Román L, Puig M, Blanco M, Castellanos M, Millán M, Roquer J, Obach V, Maestre J
Frequency and predictors of symptomatic intracerebral hemorrhage in patients with ischemic stroke treated with recombinant tissue plasminogen activator outside clinical trials.
Cerebrovascular diseases (Basel, Switzerland), 2007; 23(2-3); 85-90
FI: 2.534; Q1 / D3
