MP08-Biomarcadores e Inflamación Renal

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Proyectos

La Línea de investigación general del grupo es el estudio de la fisiología y fisiopatología de la hipertensión arterial, disfunción renal y disfunción tiroidea. Además, tiene como objetivo la búsqueda de nuevos biomarcadores de lesión y de fibrosis renal.

Líneas de investigación

Estudio de la fisiología y fisopatología de la hipertensión arterial, disfunción renal y disfunción tiroidea.

Redes de investigación

RICORS2040 (KIDNEY DISEASE) Inflamación e Inmunopatología de Órganos y Sistemas.

Palabras clave

Hipertensión, Disfunción Endotelial, Disfunción Renal, Disfunción Tiroidea, Biomarcadores.

MARIA DEL CARMEN RUIZ FUENTES

JOSE FELIX VARGAS PALOMARES

ORCID

Villanego, F; Mazuecos, A; Perez-Flores, IM; Moreso, F; Andres, A; Jimenez-Martin, C; Molina, M; Canal, C; Sanchez-Camara, LA; Zarraga, S; Ruiz-Fuentes, MD; Aladren, MJ; Melilli, E; Lopez, V; Sanchez-Alvarez, E; Crespo, M; Pascual, J

Predictors of severe COVID-19 in kidney transplant recipients in the different epidemic waves: Analysis of the Spanish Registry

AMERICAN JOURNAL OF TRANSPLANTATION, 2021;

FI:8,086; D1

Buxeda, A; Arias-Cabrales, C; Perez-Saez, MJ; Cacho, J; Pelegrin, SC; Melilli, E; Aladren, MJ; Galeano, C; Lorenzo, I; Mazuecos, A; Saura, IM; Franco, A; Ruiz-Fuentes, MD; Sanchez-Camara, LA; Siverio, O; Martin, ML; Gonzalez-Garcia, E; Lopez, V; Martin-Mo

Use and Safety of Remdesivir in Kidney Transplant Recipients With COVID-19

KIDNEY INTERNATIONAL REPORTS, 2021;

FI:4,164; Q1

Montoro-Molina, S; Quesada, A; O'Valle, F; Morales, NM; de Gracia, MD; Rodriguez-Gomez, I; Osuna, A; Wangensteen, R; Vargas, F

The Long-Term Study of Urinary Biomarkers of Renal Injury in Spontaneously Hypertensive Rats

KIDNEY & BLOOD PRESSURE RESEARCH, 2021;

FI:2,687; Q3

Pascual, J; Melilli, E; Jimenez-Martin, C; Gonzalez-Monte, E; Zarraga, S; Gutierrez-Dalmau, A; Lopez-Jimenez, V; Juega, J; Munoz-Cepeda, M; Lorenzo, I; Facundo, C; Ruiz-Fuentes, MD; Mazuecos, A; Sanchez-Alvarez, E; Crespo, M

COVID-19-related Mortality During the First 60 Days After Kidney Transplantation

EUROPEAN UROLOGY, 2020;

FI:18,728; D1

Crespo, M; Zarraga, S; Alonso, A; Beneyto, I; Corte, CD; Rodriguez, AMF; Franco, A; Hernandez, D; Gonzalez-Roncero, FM; Martin, CJ; Jimeno, L; Valdemoros, LRL; Llorente, S; Mazuecos, A; Osuna, A; Ramos, JP; Benot, AR; San Millan, JCR; Fructuoso, AS; Torre

Monitoring of Donor-specific Anti-HLA Antibodies and Management of Immunosuppression in Kidney Transplant Recipients: An Evidence-based Expert Paper

TRANSPLANTATION, 2020;

FI:4,546; D1

Macias-Ruiz, R; Jimenez-Jaimez, J; Alvarez-Lopez, M; Molina-Lerma, M; Sanchez-Millan, P; Wangensteen, R; Quesada, A; Osuna-Ortega, A; Tercedor-Sanchez, L

Effect of pulmonary vein catheter ablation on kidney function in patients with atrial fibrillation. A prospective cohort study

REVISTA ESPANOLA DE CARDIOLOGIA, 2020;

FI:4,642; Q1

Garcia, EH; Fuentes, MCR; Guindo, MCG; Gila, JDLG; Fuentes, NR; Ortega, AO

Development of Ureteral Stenosis/Obstruction in Kidney Transplant

TRANSPLANTATION PROCEEDINGS, 2020;

FI:0,784; Q4

Lara, EP; Garcia, EH; Fuentes, MDR; Molina, MC; Guindo, MDD; Ortega, AO

Plasma Cell-Rich Acute Rejection in Renal Transplantation: A Case Report

TRANSPLANTATION PROCEEDINGS, 2020;

FI:0,784; Q4

Gonzalez-Corvillo, C; Beneyto, I; Sanchez-Fructuoso, A; Perello, M; Alonso, A; Mazuecos, A; Jimenez, C; Zarraga, S; Paul, J; Lauzurica, R; Hernandez, D; Guirado, L; Franco, A; Ruiz, JC; Llorente, S; Crespo, M; Rodriguez-Benot, A; Guindo, MDD; Diaz-Corte, C; Gentil, MA

Direct-acting Antivirals for the Treatment of Kidney Transplant Patients With Chronic Hepatitis C Virus Infection in Spain: A Long-term Prospective Observational Study

TRANSPLANTATION DIRECT, 2019;

Porrini, E; Diaz, JM; Moreso, F; Lauzurrica, R; Ibernon, M; Torres, IS; Ruiz, RB; Rodriguez, AER; Mallen, PD; Bayes-Genis, B; Gainza, FJ; Osorio, JM; Osuna, A; Dominguez, R; Ruiz, JC; Sosa, AJ; Rinne, AG; Miranda, DM; Macias, M; Torres, A

Prediabetes is a risk factor for cardiovascular disease following renal transplantation

KIDNEY INTERNATIONAL, 2019;

FI:8,306; D1

Vazquez, A; Sanchez-Rodriguez, E; Vargas, F; Montoro-Molina, S; Romero, M; Espejo-Calvo, JA; Vilchez, P; Jaramillo, S; Olmo-Garcia, L; Carrasco-Pancorbo, A; de la Torre, R; Fito, M; Covas, MI; de Victoria, EM; Mesa, MD

Cardioprotective Effect of a Virgin Olive Oil Enriched with Bioactive Compounds in Spontaneously Hypertensive Rats

NUTRIENTS, 2019;

FI:4,171; Q1

Gila, JDLG; Guindo, MDD; Navarro-Mari, JM; Gutierrez-Fernandez, J

Corynebacterium jeikeium urinary tract infection and good clinical response with nitrofurantoin treatment

REVISTA ESPANOLA DE QUIMIOTERAPIA, 2019;

FI:0,76; Q4

Cruz-Bustos, T; Ibarrola-Vannucci, AK; Diaz-Lozano, I; Ramirez, JL; Osuna, A

Characterization and functionality of two members of the SPFH protein superfamily, prohibitin 1 and 2 in Leishmania major

PARASITES & VECTORS, 2018;

FI:3,163; D1

Moreso, F; Crespo, M; Ruiz, JC; Torres, A; Gutierrez-Dalmau, A; Osuna, A; Perello, M; Pascual, J; Torres, IB; Redondo-Pachon, D; Rodrigo, E; Lopez-Hoyos, M; Seron, D

Treatment of chronic antibody mediated rejection with intravenous immunoglobulins and rituximab: A multicenter, prospective, randomized, double-blind clinical trial

AMERICAN JOURNAL OF TRANSPLANTATION, 2018;

FI:6,493; D1

Gomez-Samblas, M; Bernal, D; Bolado-Ortiz, A; Vilchez, S; Bolas-Fernandez, F; Espino, AM; Trelis, M; Osuna, A

Intraperitoneal administration of the anti-IL-23 antibody prevents the establishment of intestinal nematodes in mice

SCIENTIFIC REPORTS, 2018;

FI:4,122; Q1

Toral, M; Jimenez, R; Montoro-Molina, S; Romero, M; Wangensteen, R; Duarte, J; Vargas, F

Thyroid hormones stimulate L-arginine transport in human endothelial cells

JOURNAL OF ENDOCRINOLOGY, 2018;

FI:4,012; Q1

Torro, LMD; Moreira, LR; Osuna, A

Extracellular Vesicles in Chagas Disease: A New Passenger for an Old Disease

FRONTIERS IN MICROBIOLOGY, 2018;

FI:4,019; Q1

Quesada, A; Segarra, AB; Montoro-Molina, S; de Gracia, MD; Osuna, A; O'Valle, F; Gomez-Guzman, M; Vargas, F; Wangensteen, R

Glutamyl aminopeptidase in microvesicular and exosomal fractions of urine is related with renal dysfunction in cisplatin-treated rats

PLOS ONE, 2017;

FI:2,806; Q1

Porrini, EL; Diaz, JM; Moreso, F; Mallen, PID; Torres, IS; Ibernon, M; Bayes-Genis, B; Benitez-Ruiz, R; Lampreabe, I; Lauzurrica, R; Osorio, JM; Osuna, A; Dominguez-Rollan, R; Ruiz, JC; Jimenez-Sosa, A; Gonzalez-Rinne, A; Marrero-Miranda, D; Macia, M; Garcia, J; Torres, A

Clinical evolution of post-transplant diabetes mellitus

NEPHROLOGY DIALYSIS TRANSPLANTATION, 2016;

FI:4,085; D1

Rodriguez-Gomez, I; Moliz, JN; Quesada, A; Montoro-Molina, S; Vargas-Tendero, P; Osuna, A; Wangensteen, R; Vargas, F

L-Arginine metabolism in cardiovascular and renal tissue from hyper- and hypothyroid rats

EXPERIMENTAL BIOLOGY AND MEDICINE, 2016;

FI:2,542; Q2

Gentil, MA; de la Nuez, PC; Gonzalez-Corvillo, C; de Gracia, MG; Cabello, M; Mazuecos, MA; Rodriguez-Benot, A; Ballesteros, L; Osuna, A; Alonso, M

Non-Heart-Beating Donor Kidney Transplantation Survival Is Similar to Donation After Brain Death: Comparative Study With Controls in a Regional Program

TRANSPLANTATION PROCEEDINGS, 2016;

FI:0,867; Q4

Rodriguez-Gomez, I; Moreno, JM; Jimenez, R; Quesada, A; Montoro-Molina, S; Vargas-Tendero, P; Wangensteen, R; Vargas, F

Effects of Arginase Inhibition in Hypertensive Hyperthyroid Rats

AMERICAN JOURNAL OF HYPERTENSION, 2015;

FI:2,852; Q2

Montoro-Molina, S; Quesada, A; Zafra-Ruiz, PV; O'Valle, F; Vargas, F; de Gracia, MD; Osuna, A; Wangensteen, R

Immunological detection of glutamyl aminopeptidase in urine samples from cisplatin-treated rats

PROTEOMICS CLINICAL APPLICATIONS, 2015;

FI:2,956; Q2

Wangensteen, R; Rodriguez-Gomez, I; Perez-Abud, R; Quesada, A; Montoro-Molina, S; Osuna, A; Vargas, F

Dietary salt restriction in hyperthyroid rats. Differential influence on left and right ventricular mass

EXPERIMENTAL BIOLOGY AND MEDICINE, 2015;

FI:2,165; Q3

RD21/0005/0015 ANTONIO OSUNA – RICORS20 Inflamación e inmunopatología de órganos y sistemas

Financiador: INSTITUTO DE SALUD CARLOS III

Número de expediente: RD21/0005/0015

Tiempo de ejecución: 01/01/2022 - 31/12/2022

IP: ANTONIO OSUNA ORTEGA

RD16/0009/0033 REDINREN – ANTONIO OSUNA

Financiador: INSTITUTO DE SALUD CARLOS III

Número de expediente: RD16/0009/0033

Tiempo de ejecución: 01/01/2017 - 31/12/2021

IP: ANTONIO OSUNA ORTEGA

Papel de las toxinas urémicas de origen intestinal en las calcificaciones vasculares y eventos cardiovasculares de los pacientes con enfermedad renal crónica.

Financiador: INSTITUTO DE SALUD CARLOS III

Número de expediente: PI18/01715

Tiempo de ejecución: 01/01/2019 - 31/12/2021

IP: ANTONIO OSUNA ORTEGA

MP08-Biomarcadores e Inflamación Renal

Líneas de investigación

Redes de investigación

Palabras clave

MARIA CARMEN DE GRACIA GUINDO

ANTONIO OSUNA ORTEGA

ISABEL MARIA RODRIGUEZ GOMEZ

MARIA DEL CARMEN RUIZ FUENTES

JOSE FELIX VARGAS PALOMARES

Investigación