BASES FISIOPATOLOGIA Y TERAPEUTICA MEDICA
Grupos de investigación IBS-MP-07
BASES FISIOPATOLOGIA Y TERAPEUTICA MEDICA
Grupo de investigación dedicado a profundizar en el conocimiento de las enfermedades autoinmunes sistémicas desde el punto de vista epidemiológico, clínico, genético y de inmunología básica. Además, trabaja en el estudio de los factores de riesgo asociados con el desarrollo de osteoporosis esteroidea, así como de su prevención y tratamiento.
Lineas de investigación
Palabras clave
Enfermedades Autoinmunes, Lupus, Esclerodermia, Vasculitis Sistémicas, Uveitis, Osteoporosis Y Glucocorticoídes.
| Miembro |
|---|
| PARDO CABELLO, ALFREDO JOSE |
| CALLEJAS RUBIO, JOSÉ LUIS |
| ORTEGO CENTENO, NORBERTO |
| RÍOS FERNÁNDEZ, RAQUEL |
| CEBALLOS TORRES, ANGEL |
| POCOVI GERARDINO, GABRIELA |
| SÁNCHEZ CANO, DANIEL |
| TORNERO DIVIESO, MARÍA LUCÍA |
| MÁRQUEZ ORTIZ, ANA MARÍA |
| FERNÁNDEZ ROLDÁN, MARÍA CONCEPCIÓN |
| RUEDA MEDINA, BLANCA Mª |
| MORENO HIGUERAS, MANUELA |
| CORREA RODRÍGUEZ, MARÍA |
Márquez A, Kerick M, Zhernakova A, Gutierrez-Achury J, Chen WM, Onengut-Gumuscu S, González-Álvaro I, Rodriguez-Rodriguez L, Rios-Fernández R, González-Gay MA, Coeliac Disease Immunochip Consortium, Rheumatoid Arthritis Consortium International for Immunochip (RACI), International Scleroderma Group, Type 1 Diabetes Genetics Consortium, Mayes MD, Raychaudhuri S, Rich SS, Wijmenga C, Martín J
Meta-analysis of Immunochip data of four autoimmune diseases reveals novel single-disease and cross-phenotype associations.
Genome medicine, 2018; 10(1); 97
FI: 8.898; Q1 / D1
Kuiper JJW, Setten JV, Devall M, Cretu-Stancu M, Hiddingh S, Ophoff RA, Missotten TOAR, Velthoven MV, Den Hollander AI, Hoyng CB, James E, Reeves E, Cordero-Coma M, Fonollosa A, Adán A, Martín J, Koeleman BPC, Boer JH, Pulit SL, Márquez A, Radstake TRDJ
Functionally distinct ERAP1 and ERAP2 are a hallmark of HLA-A29-(Birdshot) Uveitis.
Human molecular genetics, 2018; 27(24); 4333-4343
FI: 4.902; Q1 / D2
Soriano-Maldonado A, Morillas-de-Laguno P, Sabio JM, Gavilán-Carrera B, Rosales-Castillo A, Montalbán-Méndez C, Sáez-Urán LM, Callejas-Rubio JL, Vargas-Hitos JA
Effects of 12-week Aerobic Exercise on Arterial Stiffness, Inflammation, and Cardiorespiratory Fitness in Women with Systemic LUPUS Erythematosus: Non-Randomized Controlled Trial.
Journal of clinical medicine, 2018; 7(12);
FI: 5.583; Q1 / D1
Martorana D, Márquez A, Carmona FD, Bonatti F, Adorni A, Urban ML, Maritati F, Accorsi Buttini E, Marvisi C, Palmisano A, Rossi GM, Trivioli G, Fenaroli P, Manenti L, Nicastro M, Incerti M, Gianfreda D, Bani S, Ferretti S, Corradi D, Alberici F, Emmi G, Di Scala G, Moroni G, Percesepe A, Scheel PJ, Vermeer E, van Bommel EF, Martín J, Vaglio A
A large-scale genetic analysis reveals an autoimmune origin of idiopathic retroperitoneal fibrosis.
The Journal of allergy and clinical immunology, 2018; 142(5); 1662-1665
FI: 13.258; Q1 / D1
Martín-Varillas JL, Calvo-Río V, Beltrán E, Sánchez-Bursón J, Mesquida M, Adán A, Hernandez MV, Garfella MH, Pascual EV, Martínez-Costa L, Sellas-Fernández A, Cordero-Coma M, Díaz-Llopis M, Gallego R, Salom D, Ortego N, García-Serrano JL, Callejas-Rubio JL, Herreras JM, García-Aparicio Á, Maíz O, Blanco A, Torre I, Díaz-Valle D, Pato E, Aurrecoechea E, Caracuel MA, Gamero F, Minguez E, Carrasco-Cubero C, Olive A, Vázquez J, Ruiz-Moreno O, Manero J, Muñoz-Fernández S, Martinez MG, Rubio-Romero E, Toyos-Sáenz de Miera FJ, López Longo FJ, Nolla JM, Revenga M, González-Vela C, Loricera J, Atienza-Mateo B, Demetrio-Pablo R, Hernández JL, González-Gay MA, Blanco R
Successful Optimization of Adalimumab Therapy in Refractory Uveitis Due to Behçet's Disease.
Ophthalmology, 2018; 125(9); 1444-1451
FI: 7.479; Q1 / D1
Marí-Alfonso B, Simeón-Aznar CP, Guillén-Del Castillo A, Rubio-Rivas M, Trapiella-Martínez L, Todolí-Parra JA, Rodríguez Carballeira M, Marín-Ballvé A, Iniesta-Arandia N, Colunga-Argüelles D, Castillo-Palma MJ, Sáez-Comet L, Egurbide-Arberas MV, Ortego-Centeno N, Freire M, Vargas Hitos JA, Chamorro AJ, Madroñero-Vuelta AB, Perales-Fraile I, Pla-Salas X, Fernández-De-La-Puebla RA, Fonollosa-Pla V, Tolosa-Vilella C, RESCLE Investigators, Systemic Autoimmune Diseases Study Group (GEAS)
Hepatobiliary involvement in systemic sclerosis and the cutaneous subsets: Characteristics and survival of patients from the Spanish RESCLE Registry.
Seminars in arthritis and rheumatism, 2018; 47(6); 849-857
FI: 4.356; Q1 / D2
Burillo-Sanz S, Montes-Cano MA, García-Lozano JR, Ortiz-Fernández L, Ortego-Centeno N, García-Hernández FJ, Espinosa G, Graña-Gil G, Sánchez-Bursón J, Rosa Juliá M, Solans R, Blanco R, Barnosi-Marín AC, Gómez De la Torre R, Fanlo P, Rodríguez-Carballeira M, Rodríguez-Rodríguez L, Camps T, Castañeda S, Alegre-Sancho JJ, Martín J, González-Escribano MF
Mutational profile of rare variants in inflammasome-related genes in Behçet disease: A Next Generation Sequencing approach.
Scientific reports, 2017; 7(1); 8453
FI: 4.122; Q1 / D2
Trapiella-Martínez L, Díaz-López JB, Caminal-Montero L, Tolosa-Vilella C, Guillén-Del Castillo A, Colunga-Argüelles D, Rubio-Rivas M, Iniesta-Arandia N, Castillo-Palma MJ, Sáez-Comet L, Egurbide-Arberas MV, Ortego-Centeno N, Freire M, Vargas-Hitos JA, Ríos-Blanco JJ, Todolí-Parra JA, Rodríguez-Carballeira M, Marín-Ballvé A, Chamorro-Fernández AJ, Pla-Salas X, Madroñero-Vuelta AB, Ruiz-Muñóz M, Fonollosa-Pla V, Simeón-Aznar CP, RESCLE Investigators, on Behalf of the Autoimmune Diseases Study Group (GEAS), Spanish Society of Internal Medicine (SEMI)
Very early and early systemic sclerosis in the Spanish scleroderma Registry (RESCLE) cohort.
Autoimmunity reviews, 2017; 16(8); 796-802
FI: 8.745; Q1 / D1
Langefeld CD, Ainsworth HC, Cunninghame Graham DS, Kelly JA, Comeau ME, Marion MC, Howard TD, Ramos PS, Croker JA, Morris DL, Sandling JK, Almlöf JC, Acevedo-Vásquez EM, Alarcón GS, Babini AM, Baca V, Bengtsson AA, Berbotto GA, Bijl M, Brown EE, Brunner HI, Cardiel MH, Catoggio L, Cervera R, Cucho-Venegas JM, Dahlqvist SR, D'Alfonso S, Da Silva BM, de la Rúa Figueroa I, Doria A, Edberg JC, Endreffy E, Esquivel-Valerio JA, Fortin PR, Freedman BI, Frostegård J, García MA, de la Torre IG, Gilkeson GS, Gladman DD, Gunnarsson I, Guthridge JM, Huggins JL, James JA, Kallenberg CGM, Kamen DL, Karp DR, Kaufman KM, Kottyan LC, Kovács L, Laustrup H, Lauwerys BR, Li QZ, Maradiaga-Ceceña MA, Martín J, McCune JM, McWilliams DR, Merrill JT, Miranda P, Moctezuma JF, Nath SK, Niewold TB, Orozco L, Ortego-Centeno N, Petri M, Pineau CA, Pons-Estel BA, Pope J, Raj P, Ramsey-Goldman R, Reveille JD, Russell LP, Sabio JM, Aguilar-Salinas CA, Scherbarth HR, Scorza R, Seldin MF, Sjöwall C, Svenungsson E, Thompson SD, Toloza SMA, Truedsson L, Tusié-Luna T, Vasconcelos C, Vilá LM, Wallace DJ, Weisman MH, Wither JE, Bhangale T, Oksenberg JR, Rioux JD, Gregersen PK, Syvänen AC, Rönnblom L, Criswell LA, Jacob CO, Sivils KL, Tsao BP, Schanberg LE, Behrens TW, Silverman ED, Alarcón-Riquelme ME, Kimberly RP, Harley JB, Wakeland EK, Graham RR, Gaffney PM, Vyse TJ
Transancestral mapping and genetic load in systemic lupus erythematosus.
Nature communications, 2017; 8; 16021
FI: 12.353; Q1 / D1
López-Mejías R, Carmona FD, Castañeda S, Genre F, Remuzgo-Martínez S, Sevilla-Perez B, Ortego-Centeno N, Llorca J, Ubilla B, Mijares V, Pina T, Miranda-Filloy JA, Navas Parejo A, de Argila D, Aragües M, Rubio E, Luque ML, Blanco-Madrigal JM, Galíndez-Aguirregoikoa E, Jayne D, Blanco R, Martín J, González-Gay MA
A genome-wide association study suggests the HLA Class II region as the major susceptibility locus for IgA vasculitis.
Scientific reports, 2017; 7(1); 5088
FI: 4.122; Q1 / D2
López-Isac E, Bossini-Castillo L, Palma AB, Assassi S, Mayes MD, Simeón CP, Ortego-Centeno N, Vicente E, Tolosa C, Rubio-Rivas M, Román-Ivorra JA, Beretta L, Moroncini G, Hunzelmann N, Distler JHW, Riemekasten G, de Vries-Bouwstra J, Voskuyl AE, Radstake TRDJ, Herrick A, Denton CP, Fonseca C, Martín J
Analysis of ATP8B4 F436L Missense Variant in a Large Systemic Sclerosis Cohort.
Arthritis & rheumatology (Hoboken, N.J.), 2017; 69(6); 1337-1338
FI: 7.873; Q1 / D1
Bartoloni E, Gonzalez-Gay MA, Scirè C, Castaneda S, Gerli R, Lopez-Longo FJ, Martinez-Barrio J, Govoni M, Furini F, Pina T, Iannone F, Giannini M, Nuño L, Quartuccio L, Ortego-Centeno N, Alunno A, Specker C, Montecucco C, Triantafyllias K, Balduzzi S, Sifuentes-Giraldo WA, Paolazzi G, Bravi E, Schwarting A, Pellerito R, Russo A, Selmi C, Saketkoo LA, Fusaro E, Parisi S, Pipitone N, Franceschini F, Cavazzana I, Neri R, Barsotti S, Codullo V, Cavagna L
Clinical follow-up predictors of disease pattern change in anti-Jo1 positive anti-synthetase syndrome: Results from a multicenter, international and retrospective study.
Autoimmunity reviews, 2017; 16(3); 253-257
FI: 8.745; Q1 / D1
Cavagna L, Nuño L, Scirè CA, Govoni M, Longo FJ, Franceschini F, Neri R, Castañeda S, Sifuentes Giraldo WA, Caporali R, Iannone F, Fusaro E, Paolazzi G, Pellerito R, Schwarting A, Saketkoo LA, Ortego-Centeno N, Quartuccio L, Bartoloni E, Specker C, Pina Murcia T, La Corte R, Furini F, Foschi V, Bachiller Corral J, Airò P, Cavazzana I, Martínez-Barrio J, Hinojosa M, Giannini M, Barsotti S, Menke J, Triantafyllias K, Vitetta R, Russo A, Bogliolo L, Bajocchi G, Bravi E, Barausse G, Bortolotti R, Selmi C, Parisi S, Salaffi F, Montecucco C, González-Gay MA, AENEAS (American and European NEtwork of Antisynthetase Syndrome) Collaborative Group
Serum Jo-1 Autoantibody and Isolated Arthritis in the Antisynthetase Syndrome: Review of the Literature and Report of the Experience of AENEAS Collaborative Group.
Clinical reviews in allergy & immunology, 2017; 52(1); 71-80
FI: 6.442; Q1 / D1
Márquez A, Cordero-Coma M, Martín-Villa JM, Gorroño-Echebarría MB, Blanco R, Díaz Valle D, Del Rio MJ, Blanco A, Olea JL, Cordero Y, Capella MJ, Díaz-Llopis M, Ortego-Centeno N, Ruiz-Arruza I, Llorenç V, Adán A, Fonollosa A, Ten Berge J, Atan D, Dick AD, De Boer JH, Kuiper J, Rothova A, Martín J
New insights into the genetic component of non-infectious uveitis through an Immunochip strategy.
Journal of medical genetics, 2017; 54(1); 38-46
FI: 5.751; Q1 / D2
Correa-Rodriguez M, Schmidt-RioValle J, Rueda-Medina B
RANKL/RANK/OPG Polymorphisms and Heel Quantitative Ultrasound in Young Adults
NURSING RESEARCH, 2017; 66; 145-151
FI: 1.725; Q1 / D3
Márquez A, Vidal-Bralo L, Rodríguez-Rodríguez L, González-Gay MA, Balsa A, González-Álvaro I, Carreira P, Ortego-Centeno N, Ayala-Gutiérrez MM, García-Hernández FJ, González-Escribano MF, Sabio JM, Tolosa C, Suárez A, González A, Padyukov L, Worthington J, Vyse T, Alarcón-Riquelme ME, Martín J
A combined large-scale meta-analysis identifies COG6 as a novel shared risk locus for rheumatoid arthritis and systemic lupus erythematosus.
Annals of the rheumatic diseases, 2017; 76(1); 286-294
FI: 12.35; Q1 / D1
Zhao M, Zhou Y, Zhu B, Wan M, Jiang T, Tan Q, Liu Y, Jiang J, Luo S, Tan Y, Wu H, Renauer P, Del Mar Ayala Gutiérrez M, Castillo Palma MJ, Ortega Castro R, Fernández-Roldán C, Raya E, Faria R, Carvalho C, Alarcón-Riquelme ME, Xiang Z, Chen J, Li F, Ling G, Zhao H, Liao X, Lin Y, Sawalha AH, Lu Q
IFI44L promoter methylation as a blood biomarker for systemic lupus erythematosus.
Annals of the rheumatic diseases, 2016; 75(11); 1998-2006
FI: 12.811; Q1 / D1
Tolosa-Vilella C, Morera-Morales ML, Simeón-Aznar CP, Marí-Alfonso B, Colunga-Arguelles D, Callejas Rubio JL, Rubio-Rivas M, Freire-Dapena M, Guillén-Del Castillo A, Iniesta-Arandia N, Castillo-Palma MJ, Egurbide-Arberas M, Trapiellla-Martínez L, Vargas-Hitos JA, Todolí-Parra JA, Rodriguez-Carballeira M, Marin-Ballvé A, Pla-Salas X, Rios-Blanco JJ, Fonollosa-Pla V, RESCLE Investigators, Autoimmune Diseases Study Group (GEAS)
Digital ulcers and cutaneous subsets of systemic sclerosis: Clinical, immunological, nailfold capillaroscopy, and survival differences in the Spanish RESCLE Registry.
Seminars in arthritis and rheumatism, 2016; 46(2); 200-8
FI: 4.498; Q1 / D2
López-Isac E, Martín JE, Assassi S, Simeón CP, Carreira P, Ortego-Centeno N, Freire M, Beltrán E, Narváez J, Alegre-Sancho JJ, Spanish Scleroderma Group, Fernández-Gutiérrez B, Balsa A, Ortiz AM, González-Gay MA, Beretta L, Santaniello A, Bellocchi C, Lunardi C, Moroncini G, Gabrielli A, Witte T, Hunzelmann N, Distler JH, Riekemasten G, van der Helm-van Mil AH, de Vries-Bouwstra J, Magro-Checa C, Voskuyl AE, Vonk MC, Molberg Ø, Merriman T, Hesselstrand R, Nordin A, Padyukov L, Herrick A, Eyre S, Koeleman BP, Denton CP, Fonseca C, Radstake TR, Worthington J, Mayes MD, Martín J
Brief Report: IRF4 Newly Identified as a Common Susceptibility Locus for Systemic Sclerosis and Rheumatoid Arthritis in a Cross-Disease Meta-Analysis of Genome-Wide Association Studies.
Arthritis & rheumatology (Hoboken, N.J.), 2016; 68(9); 2338-44
FI: 6.918; Q1 / D1
López-Isac E, Campillo-Davo D, Bossini-Castillo L, Guerra SG, Assassi S, Simeón CP, Carreira P, Ortego-Centeno N, García de la Peña P, Spanish Scleroderma Group, Beretta L, Santaniello A, Bellocchi C, Lunardi C, Moroncini G, Gabrielli A, Riemekasten G, Witte T, Hunzelmann N, Kreuter A, Distler JH, Voskuyl AE, de Vries-Bouwstra J, Herrick A, Worthington J, Denton CP, Fonseca C, Radstake TR, Mayes MD, Martín J
Influence of TYK2 in systemic sclerosis susceptibility: a new locus in the IL-12 pathway.
Annals of the rheumatic diseases, 2016; 75(8); 1521-6
FI: 12.811; Q1 / D1
Correa-Rodriguez M, Rio-Valle JS, Gonzalez-Jimenez E, Rueda-Medina B
The Effects of Body Composition, Dietary Intake, and Physical Activity on Calcaneus Quantitative Ultrasound in Spanish Young Adults
BIOLOGICAL RESEARCH FOR NURSING, 2016; 18; 439-444
FI: 1.549; Q1 / D3
Márquez A, Martín J, Carmona FD
Emerging aspects of molecular biomarkers for diagnosis, prognosis and treatment response in rheumatoid arthritis.
Expert review of molecular diagnostics, 2016; 16(6); 663-75
FI: 3.1; Q1 / D3
Ferreiro-Iglesias A, Montes A, Perez-Pampin E, Cañete JD, Raya E, Magro-Checa C, Vasilopoulos Y, Sarafidou T, Caliz R, Ferrer MA, Joven B, Carreira P, Balsa A, Pascual-Salcedo D, Blanco FJ, Moreno-Ramos MJ, Fernández-Nebro A, Ordóñez MC, Alegre-Sancho JJ, Narváez J, Navarro-Sarabia F, Moreira V, Valor L, García-Portales R, Marquez A, Martin J, Gómez-Reino JJ, Gonzalez A
Replication of PTPRC as genetic biomarker of response to TNF inhibitors in patients with rheumatoid arthritis.
The pharmacogenomics journal, 2016; 16(2); 137-40
FI: 3.815; Q1 / D2
Demelo-Rodríguez P, Ortego-Centeno N, Callejas-Rubio JL
Groove sign.
European journal of internal medicine, 2016; 28; e3-4
FI: 2.96; Q1 / D2
Ortiz-Fernández L, Carmona FD, Montes-Cano MA, García-Lozano JR, Conde-Jaldón M, Ortego-Centeno N, Castillo MJ, Espinosa G, Graña-Gil G, Sánchez-Bursón J, Juliá MR, Solans R, Blanco R, Barnosi-Marín AC, Gómez de la Torre R, Fanlo P, Rodríguez-Carballeira M, Rodríguez-Rodríguez L, Camps T, Castañeda S, Alegre-Sancho JJ, Martín J, González-Escribano MF
Genetic Analysis with the Immunochip Platform in Behçet Disease. Identification of Residues Associated in the HLA Class I Region and New Susceptibility Loci.
PloS one, 2016; 11(8); e0161305
FI: 2.806; Q1 / D3
López-Mejías R, Genre F, Remuzgo-Martínez S, Pérez BS, Castañeda S, Llorca J, Ortego-Centeno N, Ubilla B, Mijares V, Pina T, Calvo-Río V, Palmou N, Miranda-Filloy JA, Parejo AN, Argila D, Sánchez-Pérez J, Rubio E, Luque ML, Blanco-Madrigal JM, Galíndez-Aguirregoikoa E, Ocejo-Vinyals JG, Martín J, Blanco R, González-Gay MA
Role of PTPN22 and CSK gene polymorphisms as predictors of susceptibility and clinical heterogeneity in patients with Henoch-Schönlein purpura (IgA vasculitis).
Arthritis research & therapy, 2015; 17; 286
FI: 3.979; Q1 / D3
López-Mejías R, Genre F, Pérez BS, Castañeda S, Ortego-Centeno N, Llorca J, Ubilla B, Remuzgo-Martínez S, Mijares V, Pina T, Calvo-Río V, Márquez A, Miranda-Filloy JA, Parejo AN, Conde-Jaldón M, Ortiz-Fernández L, Argila D, Aragües M, Rubio E, Luque ML, Blanco-Madrigal JM, Galíndez-Aguirregoikoa E, González Escribano F, Ocejo-Vinyals JG, Martín J, Blanco R, González-Gay MA
Association of HLA-B*41:02 with Henoch-Schönlein Purpura (IgA Vasculitis) in Spanish individuals irrespective of the HLA-DRB1 status.
Arthritis research & therapy, 2015; 17; 102
FI: 3.979; Q1 / D3
Mucientes A, Márquez A, Cordero-Coma M, Martín-Villa JM, Gorroño-Echebarría MB, Blanco R, Díaz Valle D, Benítez-del-Castillo JM, del Rio MJ, Blanco A, Olea JL, Cordero Y, Capella MJ, Gonzalez J, Díaz-Llopis M, Ortego-Centeno N, Adán A, Ruiz-Arruza I, Llorenç V, Fonollosa A, Martín J
Specific association of IL17A genetic variants with panuveitis.
The British journal of ophthalmology, 2015; 99(4); 566-70
FI: 3.036; Q1 / D2
Montes A, Perez-Pampin E, Navarro-Sarabia F, Moreira V, de la Serna AR, Magallares B, Vasilopoulos Y, Sarafidou T, Fernández-Nebro A, Ordóñez Mdel C, Narváez J, Cañete JD, Marquez A, Pascual-Salcedo D, Joven B, Carreira P, Moreno-Ramos MJ, Caliz R, Ferrer MA, Garcia-Portales R, Blanco FJ, Magro C, Raya E, Valor L, Alegre-Sancho JJ, Balsa A, Martin J, Plant D, Isaacs J, Morgan AW, Barton A, Wilson AG, Biologics in Rheumatoid Arthritis Genetics and Genomics Study Syndicate (BRAGGSS), Gómez-Reino JJ, Gonzalez A
Rheumatoid arthritis response to treatment across IgG1 allotype - anti-TNF incompatibility: a case-only study.
Arthritis research & therapy, 2015; 17; 63
FI: 3.979; Q1 / D3
Oparina NY, Delgado-Vega AM, Martinez-Bueno M, Magro-Checa C, Fernández C, Castro RO, Pons-Estel BA, D'Alfonso S, Sebastiani GD, Witte T, Lauwerys BR, Endreffy E, Kovács L, Escudero A, López-Pedrera C, Vasconcelos C, da Silva BM, Frostegård J, Truedsson L, Martin J, Raya E, Ortego-Centeno N, de Los Angeles Aguirre M, de Ramón Garrido E, Palma MJ, Alarcon-Riquelme ME, Kozyrev SV
PXK locus in systemic lupus erythematosus: fine mapping and functional analysis reveals novel susceptibility gene ABHD6.
Annals of the rheumatic diseases, 2015; 74(3); e14
FI: 12.384; Q1 / D1
Nakagawa K, Gonzalez-Roca E, Souto A, Kawai T, Umebayashi H, Campistol JM, Cañellas J, Takei S, Kobayashi N, Callejas-Rubio JL, Ortego-Centeno N, Ruiz-Ortiz E, Rius F, Anton J, Iglesias E, Jimenez-Treviño S, Vargas C, Fernandez-Martin J, Calvo I, Hernández-Rodríguez J, Mendez M, Dordal MT, Basagaña M, Bujan S, Yashiro M, Kubota T, Koike R, Akuta N, Shimoyama K, Iwata N, Saito MK, Ohara O, Kambe N, Yasumi T, Izawa K, Kawai T, Heike T, Yagüe J, Nishikomori R, Aróstegui JI
Somatic NLRP3 mosaicism in Muckle-Wells syndrome. A genetic mechanism shared by different phenotypes of cryopyrin-associated periodic syndromes.
Annals of the rheumatic diseases, 2015; 74(3); 603-10
FI: 12.384; Q1 / D1
Calvo-Río V, Blanco R, Beltrán E, Sánchez-Bursón J, Mesquida M, Adán A, Hernandez MV, Hernandez Garfella M, Valls Pascual E, Martínez-Costa L, Sellas-Fernández A, Cordero Coma M, Díaz-Llopis M, Gallego R, Salom D, García Serrano JL, Ortego N, Herreras JM, Fonollosa A, García-Aparicio AM, Maíz O, Blanco A, Torre I, Fernández-Espartero C, Jovani V, Peiteado-Lopez D, Pato E, Cruz J, Fernández-Cid C, Aurrecoechea E, García M, Caracuel MA, Montilla C, Atanes A, Hernandez FF, Insua S, González-Suárez S, Sánchez-Andrade A, Gamero F, Linares L, Romero-Bueno F, García AJ, Almodovar R, Minguez E, Carrasco Cubero C, Olive A, Vázquez J, Ruiz Moreno O, Jiménez-Zorzo F, Manero J, Muñoz Fernández S, Rueda-Gotor J, González-Gay MA
Anti-TNF-α therapy in patients with refractory uveitis due to Behçet's disease: a 1-year follow-up study of 124 patients.
Rheumatology (Oxford, England), 2014; 53(12); 2223-31
FI: 4.475; Q1 / D2
Márquez A, Hernández-Rodríguez J, Cid MC, Solans R, Castañeda S, Fernández-Contreras ME, Ramentol M, Morado IC, Narváez J, Gómez-Vaquero C, Martínez-Taboada VM, Ortego-Centeno N, Sopeña B, Monfort J, García-Villanueva MJ, Caminal-Montero L, de Miguel E, Blanco R, Spanish GCA Consortium, Palm O, Molberg O, Latus J, Braun N, Moosig F, Witte T, Beretta L, Santaniello A, Pazzola G, Boiardi L, Salvarani C, González-Gay MA, Martín J
Influence of the IL17A locus in giant cell arteritis susceptibility.
Annals of the rheumatic diseases, 2014; 73(9); 1742-5
FI: 10.377; Q1 / D1
Ortiz-Fernández L, Conde-Jaldón M, García-Lozano JR, Montes-Cano MA, Ortego-Centeno N, Castillo-Palma MJ, Espinosa G, Graña-Gil G, Sánchez-Bursón J, González-Gay MA, Barnosi-Marín AC, Solans R, Fanlo P, Rodríguez Carballeira M, Camps T, Castañeda S, Martín J, González-Escribano MF
GIMAP and Behçet disease: no association in the European population.
Annals of the rheumatic diseases, 2014; 73(7); 1433-4
FI: 10.377; Q1 / D1
RESCLE Registry, Espinosa G, Vargas JA, Freire M, Ríos JJ, Tolosa C, Camps MT, Callejas JL, Castillo MJ, Sáez L, Egurbide MV, Trapiella L, Fonollosa V, Simeón CP, Velasco C, Alba MA
Early- versus Late-Onset Systemic Sclerosis: Differences in Clinical Presentation and Outcome in 1037 Patients.
Medicine (Baltimore), 2014; 93; 73-81
FI: 5.723; Q1 / D1
Alba MA, Velasco C, Simeón CP, Fonollosa V, Trapiella L, Egurbide MV, Sáez L, Castillo MJ, Callejas JL, Camps MT, Tolosa C, Ríos JJ, Freire M, Vargas JA, Espinosa G, RESCLE Registry
Early- versus late-onset systemic sclerosis: differences in clinical presentation and outcome in 1037 patients.
Medicine, 2014; 93(2); 73-81
FI: 5.723; Q1 / D1
Autoimmune Diseases Study Group (GEAS) of the Spanish Society of Internal Medicine (SEMI), on behalf of the SS Study Group, Kostov B, Retamozo S, Ramentol M, Mera A, Maure B, Morera-Morales L, Ayala MD, Bosch JA, Jiménez-Heredia I, Fernández-Regal I, Red GD, Nadal ME, Canora J, Fonseca E, Akasbi M, Pinilla B, Ripoll M, Callejas JL, Pérez-Alvarez R, Fraile G, Qanneta R, Rascón FJ, Díaz-López B, Sopeña B, Casanovas A, Camps MT, Solans R, Brito-Zerón P, Ramos-Casals M
Systemic involvement in primary Sjogren's syndrome evaluated by the EULAR-SS disease activity index: analysis of 921 Spanish patients (GEAS-SS Registry).
Rheumatology (Oxford), 2014; ; 321-331
FI: 4.475; Q1 / D2
Ríos-Fernández R, Callejas-Rubio JL, Simeón-Aznar CP, Ortego-Centeno N
Health-related internet use by patients with Systemic Sclerosis and others autoimmune diseases.
Arthritis Care Res (Hoboken), 2014; ; 334-334
FI: 4.713; Q1 / D2
Ortego-Centeno N, Callejas-Rubio JL, Ríos-Fernández R, Simeón-Aznar CP
Health-related Internet use by patients with systemic sclerosis and other autoimmune diseases: comment on the article by van der Vaart et al.
Arthritis care & research, 2014; 66(2); 334
FI: 4.713; Q1 / D2
Ramos-Casals M, Brito-Zerón P, Solans R, Camps MT, Casanovas A, Sopeña B, Díaz-López B, Rascón FJ, Qanneta R, Fraile G, Pérez-Alvarez R, Callejas JL, Ripoll M, Pinilla B, Akasbi M, Fonseca E, Canora J, Nadal ME, de la Red G, Fernández-Regal I, Jiménez-Heredia I, Bosch JA, Ayala MD, Morera-Morales L, Maure B, Mera A, Ramentol M, Retamozo S, Kostov B, SS Study Group, Autoimmune Diseases Study Group (GEAS) of the Spanish Society of Internal Medicine (SEMI)
Systemic involvement in primary Sjogren's syndrome evaluated by the EULAR-SS disease activity index: analysis of 921 Spanish patients (GEAS-SS Registry).
Rheumatology (Oxford, England), 2014; 53(2); 321-31
FI: 4.475; Q1 / D2
Cenit MC, Martínez-Florensa M, Consuegra M, Bonet L, Carnero-Montoro E, Armiger N, Caballero-Baños M, Arias MT, Benitez D, Ortego-Centeno N, de Ramón E, Sabio JM, García-Hernández FJ, Tolosa C, Suárez A, González-Gay MA, Bosch E, Martín J, Lozano F
Analysis of ancestral and functionally relevant CD5 variants in systemic lupus erythematosus patients.
PloS one, 2014; 9(11); e113090
FI: 3.234; Q1 / D2
Márquez A, Solans R, Hernández-Rodríguez J, Cid MC, Castañeda S, Ramentol M, Rodriguez-Rodriguez L, Narváez J, Blanco R, Ortego-Centeno N, Spanish GCA Consortium, Palm O, Diamantopoulos AP, Braun N, Moosig F, Witte T, Beretta L, Lunardi C, Cimmino MA, Vaglio A, Salvarani C, González-Gay MA, Martín J
A candidate gene approach identifies an IL33 genetic variant as a novel genetic risk factor for GCA.
PloS one, 2014; 9(11); e113476
FI: 3.234; Q1 / D2
Conde-Jaldón M, Montes-Cano MA, García-Lozano JR, Ortiz-Fernández L, Ortego-Centeno N, González-León R, Espinosa G, Graña-Gil G, Sánchez-Bursón J, González-Gay MA, Barnosi-Marín AC, Solans R, Fanlo P, Carballeira MR, Camps T, Castañeda S, Martín J, González-Escribano MF
Epistatic interaction of ERAP1 and HLA-B in Behçet disease: a replication study in the Spanish population.
PloS one, 2014; 9(7); e102100
FI: 3.234; Q1 / D2
Aróstegui JI, Nishikomori R, Yagüe J, Heike T, Kawai T, Izawa K, Yasumi T, Kambe N, Ohara O, Saito MK, Iwata N, Shimoyama K, Akuta N, Koike R, Kubota T, Yashiro M, Bujan S, Basagaña M, Dordal MT, Mendez M, Hernández-Rodríguez J, Calvo I, Fernandez-Martin J, Vargas C, Jimenez-Treviño S, Iglesias E, Anton J, Rius F, Ruiz-Ortiz E, Ortego-Centeno N, Callejas-Rubio JL, Kobayashi N, Takei S, Cañellas J, Campistol JM, Umebayashi H, Kawai T, Souto A, Gonzalez-Roca E, Nakagawa K
Somatic NLRP3 mosaicism in Muckle-Wells syndrome. A genetic mechanism shared by different phenotypes of cryopyrin-associated periodic syndromes.
Ann Rheum Dis, 2013; ;
FI: 9.27; Q1 / D1
Carmona FD, Cénit MC, Diaz-Gallo LM, Broen JC, Simeón CP, Carreira PE, Callejas-Rubio JL, Fonollosa V, López-Longo FJ, González-Gay MA, Hunzelmann N, Riemekasten G, Witte T, Kreuter A, Distler JH, Madhok R, Shiels P, van Laar JM, Schuerwegh AJ, Vonk MC, Voskuyl AE, Fonseca C, Denton CP, Herrick A, Worthington J, Arnett FC, Tan FK, Assassi S, Radstake TR, Mayes MD, Martín J, Spanish Scleroderma Group
New insight on the Xq28 association with systemic sclerosis.
Annals of the rheumatic diseases, 2013; 72(12); 2032-8
FI: 9.27; Q1 / D1
Serrano A, Márquez A, Mackie SL, Carmona FD, Solans R, Miranda-Filloy JA, Hernández-Rodríguez J, Cid MC, Castañeda S, Morado IC, Narváez J, Blanco R, Sopeña B, García-Villanueva MJ, Monfort J, Ortego-Centeno N, Unzurrunzaga A, Marí-Alfonso B, Sánchez-Martín J, de Miguel E, Magro C, Raya E, Braun N, Latus J, Molberg O, Lie BA, Moosig F, Witte T, Morgan AW, González-Gay MA, Martín J, UK GCA Consortium Spanish GCA Consortium
Identification of the PTPN22 functional variant R620W as susceptibility genetic factor for giant cell arteritis.
Annals of the rheumatic diseases, 2013; 72(11); 1882-6
FI: 9.27; Q1 / D1
Martin JE, Assassi S, Diaz-Gallo LM, Broen JC, Simeon CP, Castellvi I, Vicente-Rabaneda E, Fonollosa V, Ortego-Centeno N, González-Gay MA, Espinosa G, Carreira P, Spanish Scleroderma Group, SLEGEN consortium, U.S. Scleroderma GWAS group, BIOLUPUS, Camps M, Sabio JM, D'alfonso S, Vonk MC, Voskuyl AE, Schuerwegh AJ, Kreuter A, Witte T, Riemekasten G, Hunzelmann N, Airo P, Beretta L, Scorza R, Lunardi C, Van Laar J, Chee MM, Worthington J, Herrick A, Denton C, Fonseca C, Tan FK, Arnett F, Zhou X, Reveille JD, Gorlova O, Koeleman BP, Radstake TR, Vyse T, Mayes MD, Alarcón-Riquelme ME, Martin J
A systemic sclerosis and systemic lupus erythematosus pan-meta-GWAS reveals new shared susceptibility loci.
Human molecular genetics, 2013; 22(19); 4021-9
FI: 6.677; Q1 / D1
Diaz-Gallo LM, Simeon CP, Broen JC, Ortego-Centeno N, Beretta L, Vonk MC, Carreira PE, Vargas S, Román-Ivorra JA, González-Gay MA, Tolosa C, López-Longo FJ, Espinosa G, Vicente EF, Hesselstrand R, Riemekasten G, Witte T, Distler JH, Voskuyl AE, Schuerwegh AJ, Shiels PG, Nordin A, Padyukov L, Hoffmann-Vold AM, Scorza R, Lunardi C, Airo P, van Laar JM, Hunzelmann N, Gathof BS, Kreuter A, Herrick A, Worthington J, Denton CP, Zhou X, Arnett FC, Fonseca C, Koeleman BP, Assasi S, Radstake TR, Mayes MD, Martín J, Spanish Scleroderma Group
Implication of IL-2/IL-21 region in systemic sclerosis genetic susceptibility.
Annals of the rheumatic diseases, 2013; 72(7); 1233-8
FI: 9.27; Q1 / D1
Bossini-Castillo L, Martin JE, Broen J, Simeon CP, Beretta L, Gorlova OY, Vonk MC, Ortego-Centeno N, Espinosa G, Carreira P, García de la Peña P, Oreiro N, Román-Ivorra JA, Castillo MJ, González-Gay MA, Sáez-Comet L, Castellví I, Schuerwegh AJ, Voskuyl AE, Hoffmann-Vold AM, Hesselstrand R, Nordin A, Lunardi C, Scorza R, van Laar JM, Shiels PG, Herrick A, Worthington J, Fonseca C, Denton C, Tan FK, Arnett FC, Assassi S, Koeleman BP, Mayes MD, Radstake TR, Martin J, Spanish Scleroderma Group
Confirmation of TNIP1 but not RHOB and PSORS1C1 as systemic sclerosis risk factors in a large independent replication study.
Annals of the rheumatic diseases, 2013; 72(4); 602-7
FI: 9.27; Q1 / D1
Serrano A, Carmona FD, Castañeda S, Solans R, Hernández-Rodríguez J, Cid MC, Prieto-González S, Miranda-Filloy JA, Rodríguez-Rodríguez L, Morado IC, Gomez-Vaquero C, Blanco R, Sopeña B, Ortego-Centeno N, Unzurrunzaga A, Marí-Alfonso B, Sánchez-Martín J, García-Villanueva MJ, Hidalgo-Conde A, Pazzola G, Boiardi L, Salvarani C, González-Gay MA, Martín J
Evidence of association of the NLRP1 gene with giant cell arteritis.
Annals of the rheumatic diseases, 2013; 72(4); 628-30
FI: 9.27; Q1 / D1
Spanish Scleroderma Group, Martín J, Mayes MD, Radstake TR, Assassi S, Tan FK, Arnett FC, Worthington J, Herrick A, Denton CP, Fonseca C, Voskuyl AE, Vonk MC, Schuerwegh AJ, van Laar JM, Shiels P, Madhok R, Distler JH, Kreuter A, Witte T, Riemekasten G, Hunzelmann N, González-Gay MA, López-Longo FJ, Fonollosa V, Callejas-Rubio JL, Carreira PE, Simeón CP, Broen JC, Diaz-Gallo LM, Cénit MC, Carmona FD
New insight on the Xq28 association with systemic sclerosis.
Ann Rheum Dis, 2013; ;
FI: 9.27; Q1 / D1
Nath SK, James JA, Criswell LA, Harley JB, BIOLUPUS and GENLES networks, Alarcón-Riquelme ME, Bae SC, Gaffney PM, Gilkeson GS, Anaya JM, Merrill JT, Moser Sivils KL, Niewold TB, Argentine Collaborative Group, Pons-Estel B, Jacob CO, Vyse TJ, Langefeld CD, Tsao BP, Freedman BI, Boackle SA, Vilá LM, Reveille JD, Petri MA, Ramsey-Goldman R, Choi J, Kim JH, Edberg JC, Alarcón GS, Brown EE, Kimberly RP, Scofield RH, Guthridge JM, Glenn SB, Kelly JA, Kaufman KM, Chung SA, Adler A, Sun C, Kim-Howard X, Namjou B
PTPN22 Association in Systemic Lupus Erythematosus (SLE) with Respect to Individual Ancestry and Clinical Sub-Phenotypes.
PLoS One, 2013; 8;
FI: 3.534; Q1 / D2
Tsao BP, Brown EE, BIOLUPUS and GENLES networks, Alarcόn-Riquelme ME, Harley JB, Hahn BH, Grossman JM, Chen W, Cantor RM, Boackle SA, Stevens AM, Criswell LA, Merrill JT, Niewold TB, Anaya JM, Gregersen PK, James JA, Sivils KM, Gaffney PM, Freedman BI, Argentine Collaborative Group, Pons-Estel BA, Vyse TJ, Alarcón GS, Vilá LM, Reveille JD, Petri MA, Ramsey-Goldman R, Kelly JA, Langefeld CD, Scofield RH, Jacob CO, Gilkeson GS, Kamen DL, Kimberly RP, Edberg JC, Kaufman KM, Sakurai D, Zhao J, Deng Y
MicroRNA-3148 modulates allelic expression of toll-like receptor 7 variant associated with systemic lupus erythematosus.
PLoS Genet, 2013; 9;
FI: 8.167; Q1 / D1
BIOGEAS study group, Ramos-Casals M, Pérez-de-Lis M, Perez-Alvarez R
Biologics-induced autoimmune diseases.
Curr Opin Rheumatol, 2013; 25; 56-64
FI: 5.073; Q1 / D2
Martín J, Radstake TR, Voskuyl AE, Vonk MC, Schuerwegh AJ, Worthington J, Herrick A, Denton C, Fonseca C, van Laar JM, Shiels P, Madhok R, Distler JH, Kreuter A, Witte T, Riemekasten G, Hunzelmann N, Lunardi C, Scorza R, Airó P, Spanish Scleroderma Group, Egurbide MV, Camps MT, Beltrán E, Sáez-Comet L, Fernández-Castro M, Callejas JL, Carreira PE, Simeón CP, Beretta L, Martin JE, Carmona FD
The systemic lupus erythematosus IRF5 risk haplotype is associated with systemic sclerosis.
PLoS One, 2013; 8;
FI: 3.534; Q1 / D2
Cénit MC, Márquez A, Cordero-Coma M, Gorroño-Echebarría MB, Fonollosa A, Adán A, Martínez-Berriotxoa A, Díaz Valle D, Pato E, Blanco R, Cañal J, Díaz-Llopis M, García Serrano JL, de Ramón E, Del Rio MJ, Martín-Villa JM, Molins B, Ortego-Centeno N, Martín J
No evidence of association between common autoimmunity STAT4 and IL23R risk polymorphisms and non-anterior uveitis.
PloS one, 2013; 8(11); e72892
FI: 3.534; Q1 / D2
Montes-Cano MA, Conde-Jaldón M, García-Lozano JR, Ortiz-Fernández L, Ortego-Centeno N, Castillo-Palma MJ, Espinosa G, Graña-Gil G, González-Gay MA, Barnosi-Marín AC, Solans R, Fanlo P, Camps T, Castañeda S, Sánchez-Bursón J, Núñez-Roldán A, Martín J, González-Escribano MF
HLA and non-HLA genes in Behçet's disease: a multicentric study in the Spanish population.
Arthritis research & therapy, 2013; 15(5); R145
FI: 4.117; Q1 / D3
Deng Y, Zhao J, Sakurai D, Kaufman KM, Edberg JC, Kimberly RP, Kamen DL, Gilkeson GS, Jacob CO, Scofield RH, Langefeld CD, Kelly JA, Ramsey-Goldman R, Petri MA, Reveille JD, Vilá LM, Alarcón GS, Vyse TJ, Pons-Estel BA, Argentine Collaborative Group, Freedman BI, Gaffney PM, Sivils KM, James JA, Gregersen PK, Anaya JM, Niewold TB, Merrill JT, Criswell LA, Stevens AM, Boackle SA, Cantor RM, Chen W, Grossman JM, Hahn BH, Harley JB, Alarcόn-Riquelme ME, BIOLUPUS and GENLES networks, Brown EE, Tsao BP
MicroRNA-3148 modulates allelic expression of toll-like receptor 7 variant associated with systemic lupus erythematosus.
PLoS genetics, 2013; 9(2); e1003336
FI: 8.167; Q1 / D1
Márquez A, Cénit MC, Cordero-Coma M, Ortego-Centeno N, Adán A, Fonollosa A, Díaz Valle D, Pato E, Blanco R, Cañal J, Díaz-Llopis M, de Ramón E, Del Rio MJ, García Serrano JL, Artaraz J, Martín-Villa JM, Llorenç V, Gorroño-Echebarría MB, Martín J
Two functional variants of IRF5 influence the development of macular edema in patients with non-anterior uveitis.
PloS one, 2013; 8(10); e76777
FI: 3.534; Q1 / D2
Carmona FD, Martin JE, Beretta L, Simeón CP, Carreira PE, Callejas JL, Fernández-Castro M, Sáez-Comet L, Beltrán E, Camps MT, Egurbide MV, Spanish Scleroderma Group, Airó P, Scorza R, Lunardi C, Hunzelmann N, Riemekasten G, Witte T, Kreuter A, Distler JH, Madhok R, Shiels P, van Laar JM, Fonseca C, Denton C, Herrick A, Worthington J, Schuerwegh AJ, Vonk MC, Voskuyl AE, Radstake TR, Martín J
The systemic lupus erythematosus IRF5 risk haplotype is associated with systemic sclerosis.
PloS one, 2013; 8(1); e54419
FI: 3.534; Q1 / D2
Diaz-Gallo LM, Sánchez E, Ortego-Centeno N, Sabio JM, García-Hernández FJ, de Ramón E, González-Gay MA, Torsten Witte null, Anders HJ, González-Escribano MF, Martin J
Evidence of new risk genetic factor to systemic lupus erythematosus: the UBASH3A gene.
PloS one, 2013; 8(4); e60646
FI: 3.534; Q1 / D2
Namjou B, Kim-Howard X, Sun C, Adler A, Chung SA, Kaufman KM, Kelly JA, Glenn SB, Guthridge JM, Scofield RH, Kimberly RP, Brown EE, Alarcón GS, Edberg JC, Kim JH, Choi J, Ramsey-Goldman R, Petri MA, Reveille JD, Vilá LM, Boackle SA, Freedman BI, Tsao BP, Langefeld CD, Vyse TJ, Jacob CO, Pons-Estel B, Argentine Collaborative Group, Niewold TB, Moser Sivils KL, Merrill JT, Anaya JM, Gilkeson GS, Gaffney PM, Bae SC, Alarcón-Riquelme ME, BIOLUPUS and GENLES Networks, Harley JB, Criswell LA, James JA, Nath SK
PTPN22 association in systemic lupus erythematosus (SLE) with respect to individual ancestry and clinical sub-phenotypes.
PloS one, 2013; 8(8); e69404
FI: 3.534; Q1 / D2
Perez-Alvarez R, Pérez-de-Lis M, Ramos-Casals M, BIOGEAS study group
Biologics-induced autoimmune diseases.
Current opinion in rheumatology, 2013; 25(1); 56-64
FI: 5.073; Q1 / D2
Martin J, Fonseca C, Radstake TR, Denton C, Worthington J, Herrick A, Shiels P, van Laar JM, Lunardi C, Hesselstrand R, Schuerwegh AJ, the Spanish Scleroderma Group, Egurbide MV, Vicente-Rabaneda E, Tolosa C, Camps MT, Castellví I, González-Gay MA, García-Portales R, Rodríguez-Rodríguez L, Carreira P, Callejas JL, Vonk MC, Broen J, Beretta L, Simeon CP, Bossini-Castillo L
KCNA5 gene is not confirmed as a systemic sclerosis-related pulmonary arterial hypertension genetic susceptibility factor.
Arthritis Res Ther, 2012; 14; R273
FI: 4.302; Q1 / D2
Bossini-Castillo L, Simeon CP, Beretta L, Broen J, Vonk MC, Callejas JL, Carreira P, Rodríguez-Rodríguez L, García-Portales R, González-Gay MA, Castellví I, Camps MT, Tolosa C, Vicente-Rabaneda E, Egurbide MV, Spanish Scleroderma Group, Schuerwegh AJ, Hesselstrand R, Lunardi C, van Laar JM, Shiels P, Herrick A, Worthington J, Denton C, Radstake TR, Fonseca C, Martin J
KCNA5 gene is not confirmed as a systemic sclerosis-related pulmonary arterial hypertension genetic susceptibility factor.
Arthritis research & therapy, 2012; 14(6); R273
FI: 4.302; Q1 / D2
Espinosa G, Cervera R, Ortego N, Adán A, Ríos-Fernández R, Mesquida M, Callejas JL, Alba MA, Perra D
Adalimumab for the treatment of Behçet's disease: experience in 19 patients.
Rheumatology (Oxford), 2012; 51; 1825-31
FI: 4.212; Q1 / D3
Perra D, Alba MA, Callejas JL, Mesquida M, Ríos-Fernández R, Adán A, Ortego N, Cervera R, Espinosa G
Adalimumab for the treatment of Behçet's disease: experience in 19 patients.
Rheumatology (Oxford, England), 2012; 51(10); 1825-31
FI: 4.212; Q1 / D3
Díaz-Llopis M, Salom D, Garcia-de-Vicuña C, Cordero-Coma M, Ortega G, Ortego N, Suarez-de-Figueroa M, Rio-Pardo MJ, Fernandez-Cid C, Fonollosa A, Blanco R, Garcia-Aparicio AM, Benitez-Del-Castillo JM, Olea JL, Arevalo JF
Treatment of refractory uveitis with adalimumab: a prospective multicenter study of 131 patients.
Ophthalmology, 2012; 119(8); 1575-81
FI: 5.563; Q1 / D1
Delgado-Vega AM, Dozmorov MG, Quirós MB, Wu YY, Martínez-García B, Kozyrev SV, Frostegård J, Truedsson L, de Ramón E, González-Escribano MF, Ortego-Centeno N, Pons-Estel BA, D'Alfonso S, Sebastiani GD, Witte T, Lauwerys BR, Endreffy E, Kovács L, Vasconcelos C, da Silva BM, Wren JD, Martin J, Castillejo-López C, Alarcón-Riquelme ME
Fine mapping and conditional analysis identify a new mutation in the autoimmunity susceptibility gene BLK that leads to reduced half-life of the BLK protein.
Annals of the rheumatic diseases, 2012; 71(7); 1219-26
FI: 9.111; Q1 / D1
Martin J, Radstake TR, González-Gay MA, Schuerwegh AJ, Voskuyl AE, Koeleman BP, Hunzelmann N, Distler JH, Kreuter A, Krieg T, Witte T, Riemekasten G, Lunardi C, Airó P, Beretta L, Spanish Scleroderma Group, Espinosa G, Gallego M, Delgado-Frías E, García-Portales R, Camps MT, Carreira P, Vonk MC, Broen J, Simeon CP, Teruel M
Analysis of the association between CD40 and CD40 ligand polymorphisms and systemic sclerosis.
Arthritis Res Ther, 2012; 14; R154
FI: 4.302; Q1 / D2
Teruel M, Simeon CP, Broen J, Vonk MC, Carreira P, Camps MT, García-Portales R, Delgado-Frías E, Gallego M, Espinosa G, Spanish Scleroderma Group, Beretta L, Airó P, Lunardi C, Riemekasten G, Witte T, Krieg T, Kreuter A, Distler JH, Hunzelmann N, Koeleman BP, Voskuyl AE, Schuerwegh AJ, González-Gay MA, Radstake TR, Martin J
Analysis of the association between CD40 and CD40 ligand polymorphisms and systemic sclerosis.
Arthritis research & therapy, 2012; 14(3); R154
FI: 4.302; Q1 / D2
Martin JE, Broen JC, Carmona FD, Teruel M, Simeon CP, Vonk MC, van 't Slot R, Rodriguez-Rodriguez L, Vicente E, Fonollosa V, Ortego-Centeno N, González-Gay MA, García-Hernández FJ, de la Peña PG, Carreira P, Spanish Scleroderma Group, Voskuyl AE, Schuerwegh AJ, van Riel PL, Kreuter A, Witte T, Riemekasten G, Airo P, Scorza R, Lunardi C, Hunzelmann N, Distler JH, Beretta L, van Laar J, Chee MM, Worthington J, Herrick A, Denton C, Tan FK, Arnett FC, Assassi S, Fonseca C, Mayes MD, Radstake TR, Koeleman BP, Martin J
Identification of CSK as a systemic sclerosis genetic risk factor through Genome Wide Association Study follow-up.
Human molecular genetics, 2012; 21(12); 2825-35
FI: 7.692; Q1 / D1
Vilardell-Tarrés M, Gil-Aguado A, Rios-Blanco JJ, Salvador-Cervello G, Gómez-de la Torre R, Sabio-Sánchez JM, Hidalgo-Tenorio C, Pallarés-Ferreres L, Esteban Marcos EM, de Ramón-Garrido E, Camps-García MT, Velilla-Marco J, Sáez-Comet L, Gallego-Villalobos M, Trapiellla-Martínez L, Egurbide-Arberas MV, Ortego-Centeno N, Callejas-Rubio JL, Sánchez-Román J, Castillo-Palma MJ, García-Hernández FJ, Campillo-Grau M, Ramos-Casals M, Espinosa-Garriga G, Tolosa-Vilella C, Fonollosa-Plá V, Simeón-Aznar CP
Registry of the Spanish network for systemic sclerosis: clinical pattern according to cutaneous subsets and immunological status.
Semin Arthritis Rheum, 2012; 41; 789-800
FI: 3.806; Q1 / D3
Simeón-Aznar CP, Fonollosa-Plá V, Tolosa-Vilella C, Espinosa-Garriga G, Ramos-Casals M, Campillo-Grau M, García-Hernández FJ, Castillo-Palma MJ, Sánchez-Román J, Callejas-Rubio JL, Ortego-Centeno N, Egurbide-Arberas MV, Trapiellla-Martínez L, Gallego-Villalobos M, Sáez-Comet L, Velilla-Marco J, Camps-García MT, de Ramón-Garrido E, Esteban Marcos EM, Pallarés-Ferreres L, Hidalgo-Tenorio C, Sabio-Sánchez JM, Gómez-de la Torre R, Salvador-Cervello G, Rios-Blanco JJ, Gil-Aguado A, Vilardell-Tarrés M
Registry of the Spanish network for systemic sclerosis: clinical pattern according to cutaneous subsets and immunological status.
Seminars in arthritis and rheumatism, 2012; 41(6); 789-800
FI: 3.806; Q1 / D3
Namjou B, Choi CB, Harley IT, Alarcón-Riquelme ME, BIOLUPUS Network, Kelly JA, Glenn SB, Ojwang JO, Adler A, Kim K, Gallant CJ, Boackle SA, Criswell LA, Kimberly RP, Brown EE, Edberg J, Alarcón GS, Stevens AM, Jacob CO, Gilkeson GS, Kamen DL, Tsao BP, Anaya JM, Kim EM, Park SY, Sung YK, Guthridge JM, Merrill JT, Petri M, Ramsey-Goldman R, Vilá LM, Niewold TB, Martin J, Pons-Estel BA, Genoma en Lupus Network, Vyse TJ, Freedman BI, Moser KL, Gaffney PM, Williams AH, Comeau ME, Reveille JD, Kang C, James JA, Scofield RH, Langefeld CD, Kaufman KM, Harley JB, Bae SC
Evaluation of TRAF6 in a large multiancestral lupus cohort.
Arthritis and rheumatism, 2012; 64(6); 1960-9
FI: 7.477; Q1 / D1
DUO Registry investigators, Matucci-Cerinic M, Zultak M, Silkey M, Rosenberg D, Schwierin B, Guillevin L, Krieg T, Denton CP
Demographic, clinical and antibody characteristics of patients with digital ulcers in systemic sclerosis: data from the DUO Registry.
Ann Rheum Dis, 2012; 71; 718-721
FI: 9.111; Q1 / D1
Sawalha AH, Richardson BC, Harley JB, Scofield RH, Tsao BP, James JA, BIOLUPUS Network, Alarcón-Riquelme ME, Vyse TJ, Moser KL, Gaffney PM, Jacob CO, Vilá LM, Criswell LA, Reveille JD, Petri M, Ramsey-Goldman R, Edberg JC, Kimberly RP, Brown EE, Niewold TB, Alarcón GS, Stevens AM, Boackle SA, Martin J, Sanchez E, Gilkeson GS, Langefeld CD, Williams A, Kaufman KM, Kelly JA, Merrill JT, Adler A, Hughes T
Analysis of autosomal genes reveals gene-sex interactions and higher total genetic risk in men with systemic lupus erythematosus.
Ann Rheum Dis, 2012; 71; 694-696
FI: 9.111; Q1 / D1
Denton CP, Krieg T, Guillevin L, Schwierin B, Rosenberg D, Silkey M, Zultak M, Matucci-Cerinic M, DUO Registry investigators
Demographic, clinical and antibody characteristics of patients with digital ulcers in systemic sclerosis: data from the DUO Registry.
Annals of the rheumatic diseases, 2012; 71(5); 718-21
FI: 9.111; Q1 / D1
Hughes T, Adler A, Merrill JT, Kelly JA, Kaufman KM, Williams A, Langefeld CD, Gilkeson GS, Sanchez E, Martin J, Boackle SA, Stevens AM, Alarcón GS, Niewold TB, Brown EE, Kimberly RP, Edberg JC, Ramsey-Goldman R, Petri M, Reveille JD, Criswell LA, Vilá LM, Jacob CO, Gaffney PM, Moser KL, Vyse TJ, Alarcón-Riquelme ME, BIOLUPUS Network, James JA, Tsao BP, Scofield RH, Harley JB, Richardson BC, Sawalha AH
Analysis of autosomal genes reveals gene-sex interactions and higher total genetic risk in men with systemic lupus erythematosus.
Annals of the rheumatic diseases, 2012; 71(5); 694-9
FI: 9.111; Q1 / D1
Spanish Scleroderma Group, Martin J, Radstake TR, Fonseca C, Denton CP, Koeleman BP, Herrick A, Chee MM, van Laar JM, Lunardi C, Hesselstrand R, Hoffmann-Vold AM, Schuerwegh AJ, Kreuter A, Witte T, Tolosa C, Narváez J, Carmen Freire Md, Beltrán E, González-Gay MA, Castillo MJ, Camps MT, Carreira P, Espinosa G, Ríos-Fernández R, Vonk MC, Broen JC, Beretta L, Simeon CP, Bossini-Castillo L
A multicenter study confirms CD226 gene association with systemic sclerosis-related pulmonary fibrosis.
Arthritis Res Ther, 2012; 14; R85
FI: 4.302; Q1 / D2
Bossini-Castillo L, Simeon CP, Beretta L, Broen JC, Vonk MC, Ríos-Fernández R, Espinosa G, Carreira P, Camps MT, Castillo MJ, González-Gay MA, Beltrán E, Carmen Freire Md, Narváez J, Tolosa C, Witte T, Kreuter A, Schuerwegh AJ, Hoffmann-Vold AM, Hesselstrand R, Lunardi C, van Laar JM, Chee MM, Herrick A, Koeleman BP, Denton CP, Fonseca C, Radstake TR, Martin J, Spanish Scleroderma Group
A multicenter study confirms CD226 gene association with systemic sclerosis-related pulmonary fibrosis.
Arthritis research & therapy, 2012; 14(2); R85
FI: 4.302; Q1 / D2
Sancho J, Zubiaur M, Ortego-Centeno N, Callejas-Rubio JL, Abián J, Carrascal M, Longobardo V, Lario A, Rosal-Vela A, Perandrés-López R, Zumaquero E, García-Rodríguez S, Pavón EJ
Increased expression and phosphorylation of the two S100A9 isoforms in mononuclear cells from patients with systemic lupus erythematosus: a proteomic signature for circulating low-density granulocytes.
J Proteomics, 2012; 75; 1778-1791
FI: 4.088; Q1 / D2
Pavón EJ, García-Rodríguez S, Zumaquero E, Perandrés-López R, Rosal-Vela A, Lario A, Longobardo V, Carrascal M, Abián J, Callejas-Rubio JL, Ortego-Centeno N, Zubiaur M, Sancho J
Increased expression and phosphorylation of the two S100A9 isoforms in mononuclear cells from patients with systemic lupus erythematosus: a proteomic signature for circulating low-density granulocytes.
Journal of proteomics, 2012; 75(6); 1778-91
FI: 4.088; Q1 / D2
UK-BIOGEAS Registry, Khamashta MA, Ramos-Casals M, Isenberg D, Emery P, Ruiz-Irastorza G, Jayne D, D'Cruz D, Rascón J, Callejas-Rubio JL, García-Hernández F, Martínez-Berriotxoa A, Catapano F, Vital EM, Sangle S, Croca S, Díaz-Lagares C
Efficacy of rituximab in 164 patients with biopsy-proven lupus nephritis: pooled data from European cohorts.
Autoimmun Rev, 2012; 11; 357-364
FI: 7.975; Q1 / D1
Díaz-Lagares C, Croca S, Sangle S, Vital EM, Catapano F, Martínez-Berriotxoa A, García-Hernández F, Callejas-Rubio JL, Rascón J, D'Cruz D, Jayne D, Ruiz-Irastorza G, Emery P, Isenberg D, Ramos-Casals M, Khamashta MA, UK-BIOGEAS Registry
Efficacy of rituximab in 164 patients with biopsy-proven lupus nephritis: pooled data from European cohorts.
Autoimmunity reviews, 2012; 11(5); 357-64
FI: 7.975; Q1 / D1
Martin J, Radstake TR, Mayes MD, Fonseca C, Assassi S, Agarwal SK, Arnett FC, Tan FK, Denton C, Worthington J, Herrick A, van Laar JM, Shiels P, Scorza R, Lunardi C, Airó P, Nordin A, Hesselstrand R, Palm Ø, Schuerwegh AJ, Voskuyl AE, Koeleman BP, Distler JH, Kreuter A, Hunzelmann N, Witte T, Riemekasten G, Coenen MJ, Spanish Scleroderma Group, Fernández Castro M, García-Hernández FJ, Carreira P, Castellví I, Callejas JL, Vonk MC, Beretta L, Simeón CP, Gorlova O, Broen J, Martin JE, Bossini-Castillo L
A GWAS follow-up study reveals the association of the IL12RB2 gene with systemic sclerosis in Caucasian populations.
Hum Mol Genet, 2012; 21; 926-933
FI: 7.692; Q1 / D1
Bossini-Castillo L, Martin JE, Broen J, Gorlova O, Simeón CP, Beretta L, Vonk MC, Callejas JL, Castellví I, Carreira P, García-Hernández FJ, Fernández Castro M, Spanish Scleroderma Group, Coenen MJ, Riemekasten G, Witte T, Hunzelmann N, Kreuter A, Distler JH, Koeleman BP, Voskuyl AE, Schuerwegh AJ, Palm Ø, Hesselstrand R, Nordin A, Airó P, Lunardi C, Scorza R, Shiels P, van Laar JM, Herrick A, Worthington J, Denton C, Tan FK, Arnett FC, Agarwal SK, Assassi S, Fonseca C, Mayes MD, Radstake TR, Martin J
A GWAS follow-up study reveals the association of the IL12RB2 gene with systemic sclerosis in Caucasian populations.
Human molecular genetics, 2012; 21(4); 926-33
FI: 7.692; Q1 / D1
Díaz-Gallo LM, Garcia S, Ortego-Centeno N, Jiménez-Alonso J, Sánchez-Román J, de Ramón E, González-Escribano MF, Balsa A, Fernández-Gutierrez B, González-Alvaro I, González-Gay MA, Martin J
Association study of BAK1 gene polymorphisms in Spanish rheumatoid arthritis and systemic lupus erythematosus cohorts.
Annals of the rheumatic diseases, 2012; 71(2); 314-6
FI: 9.111; Q1 / D1
Broen JCA, Bossini-Castillo L, van Bon L, Vonk MC, Knaapen H, Beretta L, Rueda B, Hesselstrand R, Herrick A, Worthington J, Hunzelman N, Denton CP, Fonseca C, Riemekasten G, Kiener HP, Scorza R, Simeon CP, Ortego-Centeno N, Gonzalez-Gay MA, Airo P, Coenen MJH, Martin J, Radstake TRDJ
A rare polymorphism in the gene for Toll-like receptor 2 is associated with systemic sclerosis phenotype and increases the production of inflammatory mediators
ARTHRITIS AND RHEUMATISM, 2012; 64; 264-271
FI: 7.477; Q1 / D1
Spanish Systemic Sclerosis Group, Radstake TR, Martín J, Coenen MJ, Airò P, Gonzalez-Gay MA, Ortego-Centeno N, Simeón CP, Scorza R, Kiener HP, Riemekasten G, Fonseca C, Denton CP, Hunzelman N, Worthington J, Herrick A, Hesselstrand R, Rueda B, Beretta L, Knaapen H, Vonk MC, van Bon L, Bossini-Castillo L, Broen JC
A rare polymorphism in the gene for Toll-like receptor 2 is associated with systemic sclerosis phenotype and increases the production of inflammatory mediators.
Arthritis Rheum, 2012; 64; 264-271
FI: 7.477; Q1 / D1
Alarcón-Riquelme ME, Guthridge JM, Martin J, Gaffney PM, Harley JB, Callejas JL, Witte T, D'Alfonso S, Pons-Estel BA, Frostegård J, Gilkeson G, Moser KL, Kaufman KM, Kelly JA, Merrill JT, James JA, Lu R, Domínguez N, Fineschi S, López-Egido JR, Pöllmann D, Sánchez E, Wu YY, Thavathiru E, Kozyrev SV, Wojcik J, Delgado-Vega AM, Castillejo-López C
Genetic and physical interaction of the B-cell systemic lupus erythematosus-associated genes BANK1 and BLK.
Ann Rheum Dis, 2012; 71; 136-42
FI: 9.111; Q1 / D1
Broen JC, Bossini-Castillo L, van Bon L, Vonk MC, Knaapen H, Beretta L, Rueda B, Hesselstrand R, Herrick A, Worthington J, Hunzelman N, Denton CP, Fonseca C, Riemekasten G, Kiener HP, Scorza R, Simeón CP, Ortego-Centeno N, Gonzalez-Gay MA, Airò P, Coenen MJ, Martín J, Radstake TR, Spanish Systemic Sclerosis Group
A rare polymorphism in the gene for Toll-like receptor 2 is associated with systemic sclerosis phenotype and increases the production of inflammatory mediators.
Arthritis and rheumatism, 2012; 64(1); 264-71
FI: 7.477; Q1 / D1
Beretta L, Rueda B, Marchini M, Santaniello A, Simeón CP, Fonollosa V, Caronni M, Rios-Fernandez R, Carreira P, Rodriguez-Rodriguez L, Spanish Systemic Sclerosis Group, Moreno A, López-Nevot MA, Escalera A, González-Escribano MF, Martin J, Scorza R
Analysis of Class II human leucocyte antigens in Italian and Spanish systemic sclerosis.
Rheumatology (Oxford, England), 2012; 51(1); 52-9
FI: 4.212; Q1 / D3
Carmona FD, Gutala R, Simeón CP, Carreira P, Ortego-Centeno N, Vicente-Rabaneda E, García-Hernández FJ, García de la Peña P, Fernández-Castro M, Martínez-Estupiñán L, Egurbide MV, Tsao BP, Gourh P, Agarwal SK, Assassi S, Mayes MD, Arnett FC, Tan FK, Martín J, Spanish Scleroderma Group
Novel identification of the IRF7 region as an anticentromere autoantibody propensity locus in systemic sclerosis.
Annals of the rheumatic diseases, 2012; 71(1); 114-9
FI: 9.111; Q1 / D1
Castillejo-López C, Delgado-Vega AM, Wojcik J, Kozyrev SV, Thavathiru E, Wu YY, Sánchez E, Pöllmann D, López-Egido JR, Fineschi S, Domínguez N, Lu R, James JA, Merrill JT, Kelly JA, Kaufman KM, Moser KL, Gilkeson G, Frostegård J, Pons-Estel BA, D'Alfonso S, Witte T, Callejas JL, Harley JB, Gaffney PM, Martin J, Guthridge JM, Alarcón-Riquelme ME
Genetic and physical interaction of the B-cell systemic lupus erythematosus-associated genes BANK1 and BLK.
Annals of the rheumatic diseases, 2012; 71(1); 136-42
FI: 9.111; Q1 / D1
BIOGEAS Study Group, Ramos-Casals M, Forns X, Sanchez-Tapias JM, Bosch X, Bové A, Retamozo S, Pérez-de-Lis M, Brito-Zerón P, Lopez-Roses L, García-Hernández F, Díaz-Lagares C, Pérez-Alvarez R
Hepatitis B virus (HBV) reactivation in patients receiving tumor necrosis factor (TNF)-targeted therapy: analysis of 257 cases.
Medicine (Baltimore), 2011; 90; 359-371
FI: 4.35; Q1 / D1
Carmona FD, Simeon CP, Beretta L, Carreira P, Vonk MC, Ríos-Fernández R, Espinosa G, Navarrete N, Vicente-Rabaneda E, Rodríguez-Rodríguez L, Tolosa C, García-Hernández FJ, Castellví I, Egurbide MV, Fonollosa V, González-Gay MA, Rodríguez-Carballeira M, Díaz-Gónzalez F, Sáez-Comet L, Hesselstrand R, Riemekasten G, Witte T, Voskuyl AE, Schuerwegh AJ, Madhok R, Shiels P, Fonseca C, Denton C, Nordin A, Palm Ø, Hoffmann-Vold AM, Airó P, Scorza R, Lunardi C, van Laar JM, Hunzelmann N, Kreuter A, Herrick A, Worthington J, Koeleman BP, Radstake TR, Martín J
Association of a non-synonymous functional variant of the ITGAM gene with systemic sclerosis.
Annals of the rheumatic diseases, 2011; 70(11); 2050-2
FI: 8.727; Q1 / D1
Pérez-Alvarez R, Díaz-Lagares C, García-Hernández F, Lopez-Roses L, Brito-Zerón P, Pérez-de-Lis M, Retamozo S, Bové A, Bosch X, Sanchez-Tapias JM, Forns X, Ramos-Casals M, BIOGEAS Study Group
Hepatitis B virus (HBV) reactivation in patients receiving tumor necrosis factor (TNF)-targeted therapy: analysis of 257 cases.
Medicine, 2011; 90(6); 359-71
FI: 4.35; Q1 / D1
BIOGEAS Study Group, Ramos-Casals M, Castillo-Palma MJ, Ortego-Centeno N, Camps MT, Canora-Lebrato J, Sáez L, Gómez-de-la-Torre R, Hidalgo C, Oristrell J, Selva-O'Callaghan A, Caminal-Montero L, Rascón J, Martínez-Berriotxoa A, Callejas JL, Ayala-Gutiérrez MM, García-Hernández FJ, Pérez-Alvarez R, Díaz-Lagares C
Rates of, and risk factors for, severe infections in patients with systemic autoimmune diseases receiving biological agents off-label.
Arthritis Res Ther, 2011; 13; 112-112
FI: 4.445; Q1 / D3
Gorlova O, Martin JE, Rueda B, Koeleman BP, Ying J, Teruel M, Diaz-Gallo LM, Broen JC, Vonk MC, Simeon CP, Alizadeh BZ, Coenen MJ, Voskuyl AE, Schuerwegh AJ, van Riel PL, Vanthuyne M, van 't Slot R, Italiaander A, Ophoff RA, Hunzelmann N, Fonollosa V, Ortego-Centeno N, González-Gay MA, García-Hernández FJ, González-Escribano MF, Airo P, van Laar J, Worthington J, Hesselstrand R, Smith V, de Keyser F, Houssiau F, Chee MM, Madhok R, Shiels PG, Westhovens R, Kreuter A, de Baere E, Witte T, Padyukov L, Nordin A, Scorza R, Lunardi C, Lie BA, Hoffmann-Vold AM, Palm O, García de la Peña P, Carreira P, Spanish Scleroderma Group, Varga J, Hinchcliff M, Lee AT, Gourh P, Amos CI, Wigley FM, Hummers LK, Nelson JL, Riemekasten G, Herrick A, Beretta L, Fonseca C, Denton CP, Gregersen PK, Agarwal S, Assassi S, Tan FK, Arnett FC, Radstake TR, Mayes MD, Martin J
Identification of novel genetic markers associated with clinical phenotypes of systemic sclerosis through a genome-wide association strategy.
PLoS genetics, 2011; 7(7); e1002178
FI: 8.694; Q1 / D1
Sawalha AH, Harley JB, Nath SK, BIOLUPUS Network, Alarcón-Riquelme ME, Vyse TJ, Merrill JT, Gaffney PM, Moser KL, Gilkeson GS, James JA, Alarcón GS, Vilá LM, Brown EE, Martín J, Reveille JD, Petri M, Ramsey-Goldman R, Edberg JC, Kimberly RP, Sanchez E, Ziegler J, Langefeld CD, Kaufman KM, Kelly JA, Kim-Howard X, Hughes T
Fine-mapping and transethnic genotyping establish IL2/IL21 genetic association with lupus and localize this genetic effect to IL21.
Arthritis Rheum, 2011; 63; 1689-1697
FI: 7.866; Q1 / D1
Hughes T, Kim-Howard X, Kelly JA, Kaufman KM, Langefeld CD, Ziegler J, Sanchez E, Kimberly RP, Edberg JC, Ramsey-Goldman R, Petri M, Reveille JD, Martín J, Brown EE, Vilá LM, Alarcón GS, James JA, Gilkeson GS, Moser KL, Gaffney PM, Merrill JT, Vyse TJ, Alarcón-Riquelme ME, BIOLUPUS Network, Nath SK, Harley JB, Sawalha AH
Fine-mapping and transethnic genotyping establish IL2/IL21 genetic association with lupus and localize this genetic effect to IL21.
Arthritis and rheumatism, 2011; 63(6); 1689-97
FI: 7.866; Q1 / D1
BIOGEAS Study Group, Bosch X, Xaubet A, Perez-de-Lis M, Perez-Alvarez R, Ramos-Casals M
Pulmonary disorders induced by monoclonal antibodies in patients with rheumatologic autoimmune diseases.
Am J Med, 2011; 124; 386-394
FI: 5.43; Q1 / D1
Ramos-Casals M, Perez-Alvarez R, Perez-de-Lis M, Xaubet A, Bosch X, BIOGEAS Study Group
Pulmonary disorders induced by monoclonal antibodies in patients with rheumatologic autoimmune diseases.
The American journal of medicine, 2011; 124(5); 386-94
FI: 5.43; Q1 / D1
Varadé J, Palomino-Morales R, Ortego-Centeno N, Díaz-Rubio M, Fernández-Gutiérrez B, González-Gay MÁ, Pascual-Salcedo D, Balsa A, Iglesias A, Gómez-García M, Witte T, Radstake TR, Coenen MJ, Urcelay E, Martín J
Analysis of the REL polymorphism rs13031237 in autoimmune diseases.
Annals of the rheumatic diseases, 2011; 70(4); 711-2
FI: 8.727; Q1 / D1
Bossini-Castillo L, Broen JC, Simeon CP, Beretta L, Vonk MC, Ortego-Centeno N, Espinosa G, Carreira P, Camps MT, Navarrete N, González-Escribano MF, Vicente-Rabaneda E, Rodríguez L, Tolosa C, Román-Ivorra JA, Gómez-Gracia I, García-Hernández FJ, Castellví I, Gallego M, Fernández-Nebro A, García-Portales R, Egurbide MV, Fonollosa V, de la Peña PG, Pros A, González-Gay MA, Hesselstrand R, Riemekasten G, Witte T, Coenen MJ, Koeleman BP, Houssiau F, Smith V, de Keyser F, Westhovens R, De Langhe E, Voskuyl AE, Schuerwegh AJ, Chee MM, Madhok R, Shiels P, Fonseca C, Denton C, Claes K, Padykov L, Nordin A, Palm O, Lie BA, Airó P, Scorza R, van Laar JM, Hunzelmann N, Kreuter A, Herrick A, Worthington J, Radstake TR, Martín J, Rueda B
A replication study confirms the association of TNFSF4 (OX40L) polymorphisms with systemic sclerosis in a large European cohort.
Annals of the rheumatic diseases, 2011; 70(4); 638-41
FI: 8.727; Q1 / D1
Diaz-Gallo LM, Gourh P, Broen J, Simeon C, Fonollosa V, Ortego-Centeno N, Agarwal S, Vonk MC, Coenen M, Riemekasten G, Hunzelmann N, Hesselstrand R, Tan FK, Reveille JD, Assassi S, García-Hernandez FJ, Carreira P, Camps MT, Fernandez-Nebro A, de la Peña PG, Nearney T, Hilda D, González-Gay MA, Airo P, Beretta L, Scorza R, Herrick A, Worthington J, Pros A, Gómez-Gracia I, Trapiella L, Espinosa G, Castellvi I, Witte T, de Keyser F, Vanthuyne M, Mayes MD, Radstake TR, Arnett FC, Martin J, Rueda B
Analysis of the influence of PTPN22 gene polymorphisms in systemic sclerosis.
Annals of the rheumatic diseases, 2011; 70(3); 454-62
FI: 8.727; Q1 / D1
Boteva L, IMAGEN, Wu YL, Cortes-Hernández J, Martin J, Vyse TJ, Fernando MM
Determination of the loss of function complement C4 exon 29 CT insertion using a novel paralog-specific assay in healthy UK and Spanish populations.
PloS one, 2011; 6(8); e22128
FI: 4.092; Q1 / D2
Díaz-Lagares C, Pérez-Alvarez R, García-Hernández FJ, Ayala-Gutiérrez MM, Callejas JL, Martínez-Berriotxoa A, Rascón J, Caminal-Montero L, Selva-O'Callaghan A, Oristrell J, Hidalgo C, Gómez-de-la-Torre R, Sáez L, Canora-Lebrato J, Camps MT, Ortego-Centeno N, Castillo-Palma MJ, Ramos-Casals M, BIOGEAS Study Group
Rates of, and risk factors for, severe infections in patients with systemic autoimmune diseases receiving biological agents off-label.
Arthritis research & therapy, 2011; 13(4); R112
FI: 4.445; Q1 / D3
García-Lozano JR, Abad C, Escalera A, Torres B, Fernández O, García A, Sánchez-Román J, Sabio JM, Ortego-Centeno N, Raya-Alvarez E, Núñez-Roldán A, Martín J, González-Escribano MF
Identification of HAVCR1 gene haplotypes associated with mRNA expression levels and susceptibility to autoimmune diseases.
Human genetics, 2010; 128(2); 221-9
FI: 5.047; Q1 / D2
Ortego-Centeno N, Fernández-Pugnaire MA, Callejas-Rubio JL, Sanchez-Cano D, Arias-Santiago S
Adalimumab treatment for SAPHO syndrome.
Acta Derm Venereol, 2010; 90; 301-302
FI: 2.78; Q1 / D2
Arias-Santiago S, Sanchez-Cano D, Callejas-Rubio JL, Fernández-Pugnaire MA, Ortego-Centeno N
Adalimumab treatment for SAPHO syndrome.
Acta dermato-venereologica, 2010; 90(3); 301-2
FI: 2.78; Q1 / D2
Radstake TR, Gorlova O, Rueda B, Martin JE, Alizadeh BZ, Palomino-Morales R, Coenen MJ, Vonk MC, Voskuyl AE, Schuerwegh AJ, Broen JC, van Riel PL, van 't Slot R, Italiaander A, Ophoff RA, Riemekasten G, Hunzelmann N, Simeon CP, Ortego-Centeno N, González-Gay MA, González-Escribano MF, Spanish Scleroderma Group, Airo P, van Laar J, Herrick A, Worthington J, Hesselstrand R, Smith V, de Keyser F, Houssiau F, Chee MM, Madhok R, Shiels P, Westhovens R, Kreuter A, Kiener H, de Baere E, Witte T, Padykov L, Klareskog L, Beretta L, Scorza R, Lie BA, Hoffmann-Vold AM, Carreira P, Varga J, Hinchcliff M, Gregersen PK, Lee AT, Ying J, Han Y, Weng SF, Amos CI, Wigley FM, Hummers L, Nelson JL, Agarwal SK, Assassi S, Gourh P, Tan FK, Koeleman BP, Arnett FC, Martin J, Mayes MD
Genome-wide association study of systemic sclerosis identifies CD247 as a new susceptibility locus.
Nature genetics, 2010; 42(5); 426-9
FI: 36.377; Q1 / D1
Kurreeman FA, Goulielmos GN, Alizadeh BZ, Rueda B, Houwing-Duistermaat J, Sanchez E, Bevova M, Radstake TR, Vonk MC, Galanakis E, Ortego N, Verduyn W, Zervou MI, Roep BO, Dema B, Espino L, Urcelay E, Boumpas DT, van den Berg LH, Wijmenga C, Koeleman BP, Huizinga TW, Toes RE, Martin J, AADEA Group, SLEGEN Consortium
The TRAF1-C5 region on chromosome 9q33 is associated with multiple autoimmune diseases.
Annals of the rheumatic diseases, 2010; 69(4); 696-9
FI: 9.082; Q1 / D1
Rueda B, Gourh P, Broen J, Agarwal SK, Simeon C, Ortego-Centeno N, Vonk MC, Coenen M, Riemekasten G, Hunzelmann N, Hesselstrand R, Tan FK, Reveille JD, Assassi S, Garcia-Hernandez FJ, Carreira P, Camps M, Fernandez-Nebro A, Garcia de la Peña P, Nearney T, Hilda D, Gónzalez-Gay MA, Airo P, Beretta L, Scorza R, Radstake TR, Mayes MD, Arnett FC, Martin J
BANK1 functional variants are associated with susceptibility to diffuse systemic sclerosis in Caucasians.
Annals of the rheumatic diseases, 2010; 69(4); 700-5
FI: 9.082; Q1 / D1
BIOGEAS Study Group, Khamashta MA, Cuadrado MJ, Diaz-Lagares C, Roberto-Perez-Alvarez, Ramos-Casals M
Autoimmune diseases induced by biological agents: a double-edged sword?
Autoimmun Rev, 2010; 9; 188-193
FI: 6.556; Q1 / D2
Jiménez-Alonso J, Callejas-Rubio JL, Ortego-Centeno N, Hidalgo-Tenorio C, Robles-Ortega H, Coín MA, Sabio-Sánchez JM, Peralta-Ramírez MI, Navarrete-Navarrete N
Efficacy of cognitive behavioural therapy for the treatment of chronic stress in patients with lupus erythematosus: a randomized controlled trial.
Psychother Psychosom, 2010; 79; 107-15
FI: 6.0; Q1 / D1
Serrano-Ortega S, Ortego-Centeno N, Callejas-Rubio JL, Falcón CS, Aneiros-Fernández J, Fernández-Pugnaire MA, Arias-Santiago S
Recurrent telangiectasias on the cheek: angiolupoid sarcoidosis.
Am J Med, 2010; 123; e7-e8
FI: 5.115; Q1 / D1
Martin J, Gonzalez-Gay MA, Fernandez-Gutierrez B, Callejas-Rubio JL, Miranda-Filloy JA, Castañeda S, Morado IC, Torres O, Vazquez-Rodriguez TR, Palomino-Morales RJ
Association between IL-18 gene polymorphisms and biopsy-proven giant cell arteritis.
Arthritis Res Ther, 2010; 12; R51
FI: 4.357; Q1 / D3
Navarrete-Navarrete N, Peralta-Ramírez MI, Sabio-Sánchez JM, Coín MA, Robles-Ortega H, Hidalgo-Tenorio C, Ortego-Centeno N, Callejas-Rubio JL, Jiménez-Alonso J
Efficacy of cognitive behavioural therapy for the treatment of chronic stress in patients with lupus erythematosus: a randomized controlled trial.
Psychotherapy and psychosomatics, 2010; 79(2); 107-15
FI: 6.0; Q1 / D1
Arias-Santiago S, Santiago SA, Fernández-Pugnaire MA, Aneiros-Fernández J, Falcón CS, Callejas-Rubio JL, Ortego-Centeno N, Serrano-Ortega S
Recurrent telangiectasias on the cheek: angiolupoid sarcoidosis.
The American journal of medicine, 2010; 123(1); e7-8
FI: 5.115; Q1 / D1
Palomino-Morales RJ, Vazquez-Rodriguez TR, Torres O, Morado IC, Castañeda S, Miranda-Filloy JA, Callejas-Rubio JL, Fernandez-Gutierrez B, Gonzalez-Gay MA, Martin J
Association between IL-18 gene polymorphisms and biopsy-proven giant cell arteritis.
Arthritis research & therapy, 2010; 12(2); R51
FI: 4.357; Q1 / D3
Ramos-Casals M, Roberto-Perez-Alvarez null, Diaz-Lagares C, Cuadrado MJ, Khamashta MA, BIOGEAS Study Group
Autoimmune diseases induced by biological agents: a double-edged sword?
Autoimmunity reviews, 2010; 9(3); 188-93
FI: 6.556; Q1 / D2
Abelson AK, Delgado-Vega AM, Kozyrev SV, Sánchez E, Velázquez-Cruz R, Eriksson N, Wojcik J, Linga Reddy MV, Lima G, D'Alfonso S, Migliaresi S, Baca V, Orozco L, Witte T, Ortego-Centeno N, AADEA group, Abderrahim H, Pons-Estel BA, Gutiérrez C, Suárez A, González-Escribano MF, Martin J, Alarcón-Riquelme ME
STAT4 associates with systemic lupus erythematosus through two independent effects that correlate with gene expression and act additively with IRF5 to increase risk.
Annals of the rheumatic diseases, 2009; 68(11); 1746-53
FI: 8.111; Q1 / D1
Sánchez E, Palomino-Morales RJ, Ortego-Centeno N, Jiménez-Alonso J, González-Gay MA, López-Nevot MA, Sánchez-Román J, de Ramón E, González-Escribano MF, Pons-Estel BA, D'Alfonso S, Sebastiani GD, Italian collaborative group, Alarcón-Riquelme ME, Martín J
Identification of a new putative functional IL18 gene variant through an association study in systemic lupus erythematosus.
Human molecular genetics, 2009; 18(19); 3739-48
FI: 7.386; Q1 / D1
Rueda B, Simeon C, Hesselstrand R, Herrick A, Worthington J, Ortego-Centeno N, Riemekasten G, Fonollosa V, Vonk MC, van den Hoogen FH, Sanchez-Román J, Aguirre-Zamorano MA, García-Portales R, Pros A, Camps MT, Gonzalez-Gay MA, Gonzalez-Escribano MF, Coenen MJ, Lambert N, Nelson JL, Radstake TR, Martin J
A large multicentre analysis of CTGF -945 promoter polymorphism does not confirm association with systemic sclerosis susceptibility or phenotype.
Annals of the rheumatic diseases, 2009; 68(10); 1618-20
FI: 8.111; Q1 / D1
Ortego-Centeno N, Fernández-Pugnaire MA, Callejas-Rubio JL, Girón-Prieto MS, Arias-Santiago SA
Lupus pernio or chilblain lupus?: two different entities.
Chest, 2009; 136; 946-947
FI: 6.36; Q1 / D1
Arias-Santiago SA, Girón-Prieto MS, Callejas-Rubio JL, Fernández-Pugnaire MA, Ortego-Centeno N
Lupus pernio or chilblain lupus?: two different entities.
Chest, 2009; 136(3); 946-7; author reply 947
FI: 6.36; Q1 / D1
Rueda B, Broen J, Simeon C, Hesselstrand R, Diaz B, Suárez H, Ortego-Centeno N, Riemekasten G, Fonollosa V, Vonk MC, van den Hoogen FH, Sanchez-Román J, Aguirre-Zamorano MA, García-Portales R, Pros A, Camps MT, Gonzalez-Gay MA, Coenen MJ, Airo P, Beretta L, Scorza R, van Laar J, Gonzalez-Escribano MF, Nelson JL, Radstake TR, Martin J
The STAT4 gene influences the genetic predisposition to systemic sclerosis phenotype.
Human molecular genetics, 2009; 18(11); 2071-7
FI: 7.386; Q1 / D1
Liu K, Li QZ, Delgado-Vega AM, Abelson AK, Sánchez E, Kelly JA, Li L, Liu Y, Zhou J, Yan M, Ye Q, Liu S, Xie C, Zhou XJ, Chung SA, Pons-Estel B, Witte T, de Ramón E, Bae SC, Barizzone N, Sebastiani GD, Merrill JT, Gregersen PK, Gilkeson GG, Kimberly RP, Vyse TJ, Kim I, D'Alfonso S, Martin J, Harley JB, Criswell LA, Profile Study Group, Italian Collaborative Group, German Collaborative Group, Spanish Collaborative Group, Argentinian Collaborative Group, SLEGEN Consortium, Wakeland EK, Alarcón-Riquelme ME, Mohan C
Kallikrein genes are associated with lupus and glomerular basement membrane-specific antibody-induced nephritis in mice and humans.
The Journal of clinical investigation, 2009; 119(4); 911-23
FI: 15.387; Q1 / D1
Ortego-Centeno N, Ruiz-Villaverde R, Callejas-Rubio JL, Sánchez-Cano D
Recalcitrant, recurrent aphthous stomatitis successfully treated with adalimumab.
J Eur Acad Dermatol Venereol, 2009; 23; 206-206
FI: 2.787; Q1 / D3
Sánchez-Cano D, Callejas-Rubio JL, Ruiz-Villaverde R, Ortego-Centeno N
Recalcitrant, recurrent aphthous stomatitis successfully treated with adalimumab.
Journal of the European Academy of Dermatology and Venereology : JEADV, 2009; 23(2); 206
FI: 2.787; Q1 / D3
Orrú V, Tsai SJ, Rueda B, Fiorillo E, Stanford SM, Dasgupta J, Hartiala J, Zhao L, Ortego-Centeno N, D'Alfonso S, Italian Collaborative Group, Arnett FC, Wu H, Gonzalez-Gay MA, Tsao BP, Pons-Estel B, Alarcon-Riquelme ME, He Y, Zhang ZY, Allayee H, Chen XS, Martin J, Bottini N
A loss-of-function variant of PTPN22 is associated with reduced risk of systemic lupus erythematosus.
Human molecular genetics, 2009; 18(3); 569-79
FI: 7.386; Q1 / D1
Rueda B, Broen J, Torres O, Simeon C, Ortego-Centeno N, Schrijvenaars MM, Vonk MC, Fonollosa V, van den Hoogen FH, Coenen MJ, Sanchez-Román J, Aguirre-Zamorano MA, García-Portales R, Pros A, Camps MT, Gonzalez-Gay MA, Martin J, Radstake TR
The interleukin 23 receptor gene does not confer risk to systemic sclerosis and is not associated with systemic sclerosis disease phenotype.
Annals of the rheumatic diseases, 2009; 68(2); 253-6
FI: 8.111; Q1 / D1
Rios-Fernández R, Gutierrez-Salmerón MT, Callejas-Rubio JL, Fernández-Pugnaire M, Ortego-Centeno N
Late-onset neutropenia following rituximab treatment in patients with autoimmune diseases.
The British journal of dermatology, 2007; 157(6); 1271-3
FI: 3.503; Q1 / D1
Martín J, López-Nevot MA, Jimenez-Alonso J, Ortego-Centeno N, Sabio JM, Callejas JL, Rueda B, Sánchez E
Analysis of interleukin-23 receptor (IL23R) gene polymorphisms in systemic lupus erythematosus.
Tissue Antigens, 2007; 70; 233-7
FI: 2.245; Q1 / D3
Sánchez E, Rueda B, Callejas JL, Sabio JM, Ortego-Centeno N, Jimenez-Alonso J, López-Nevot MA, Martín J
Analysis of interleukin-23 receptor (IL23R) gene polymorphisms in systemic lupus erythematosus.
Tissue antigens, 2007; 70(3); 233-7
FI: 2.245; Q1 / D3
Sánchez E, Abelson AK, Sabio JM, González-Gay MA, Ortego-Centeno N, Jiménez-Alonso J, de Ramón E, Sánchez-Román J, López-Nevot MA, Gunnarsson I, Svenungsson E, Sturfelt G, Truedsson L, Jönsen A, González-Escribano MF, Witte T, German Systemic Lupus Erythematosus Study Group, Alarcón-Riquelme ME, Martín J
Association of a CD24 gene polymorphism with susceptibility to systemic lupus erythematosus.
Arthritis and rheumatism, 2007; 56(9); 3080-6
FI: 7.677; Q1 / D1
Sánchez E, Alizadeh BZ, Valdigem G, Ortego-Centeno N, Jiménez-Alonso J, de Ramón E, García A, López-Nevot MA, Wijmenga C, Martín J, Koeleman BP
MYO9B gene polymorphisms are associated with autoimmune diseases in Spanish population.
Human immunology, 2007; 68(7); 610-5
FI: 2.901; Q1 / D2
Ortego-Centeno N, Tomás-Jiménez C, Rios-Fernández R, Callejas-Rubio JL
Corticosteroids in preventing severe lupus flares: do all patients have the same risk? Comment on the article by Tseng et al.
Arthritis Rheum, 2007; 56; 2098-2099
FI: 7.677; Q1 / D1
Callejas-Rubio JL, Rios-Fernández R, Tomás-Jiménez C, Ortego-Centeno N
Corticosteroids in preventing severe lupus flares: do all patients have the same risk? Comment on the article by Tseng et al.
Arthritis and rheumatism, 2007; 56(6); 2098-9; author reply 2099
FI: 7.677; Q1 / D1
Callejas JL, Moreno E, Martin P, Lopez-Perez L, Ortego N
Stress-induced pulmonary systolic hypertension in patients with scleroderma.
Chest, 2007; 131(4); 1267; author reply 1267
FI: 4.143; Q1 / D1
Ortego-Centeno N, Ríos-Fernández R, Callejas-Rubio JL, Sánchez-Cano D
Use of rituximab in Wegener's granulomatosis: comment on the article by Wong.
Nephrol Dial Transplant, 2007; 22; 958-959
FI: 3.167; Q1 / D2
Sánchez-Cano D, Callejas-Rubio JL, Ríos-Fernández R, Ortego-Centeno N
Use of rituximab in Wegener's granulomatosis: comment on the article by Wong.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2007; 22(3); 958-9; author reply 959
FI: 3.167; Q1 / D2
Ortego-Centeno N, Gómez-Morales M, Vilanova-Mateu A, Callejas-Rubio JL, Sánchez-Cano D
Intravascular lymphoma in a patient with systemic lupus erythematosus: a case report.
Lupus, 2007; 16; 525-528
FI: 2.248; Q1 / D3
Ortego N, Lopez-Perez L, Martin P, Moreno E, Callejas JL
Stress-induced pulmonary systolic hypertension in patients with scleroderma.
Chest, 2007; 131; 1267; auth
FI: 4.143; Q1 / D1
Ortego-Centeno N, Fernández-Pugnaire M, Callejas-Rubio JL, Gutierrez-Salmerón MT, Rios-Fernández R
Late-onset neutropenia following rituximab treatment in patients with autoimmune diseases.
Br J Dermatol, 2007; 157; 1271-1273
FI: 3.503; Q1 / D1
Sánchez-Cano D, Callejas-Rubio JL, Vilanova-Mateu A, Gómez-Morales M, Ortego-Centeno N
Intravascular lymphoma in a patient with systemic lupus erythematosus: a case report.
Lupus, 2007; 16(7); 525-8
FI: 2.248; Q1 / D3
Título del proyecto: Identificación de los mecanismos patogénicos implicados en el desarrollo de la arteritis de células gigantes mediante secuenciación del transcriptoma de células T individuales
Financiador: INSTITUTO DE SALUD CARLOS III
Nº Expediente: PI18/00040
Ejecución: 2019-2021
IP: ANA MARÍA MÁRQUEZ ORTIZ
Título del proyecto: Study of the molecular basis of giant cell arteritis by integrating genomic, transcriptomic and methylation data.
Financiador: INSTITUTO DE SALUD CARLOS III
Nº Expediente: CP17/00008-P
Ejecución: 2018-2020
IP: ANA MARÍA MÁRQUEZ ORTIZ
Título del proyecto: CP17/00008 - MIGUEL SERVET TIPO I - MARQUEZ ORTIZ, ANA MARIA
Financiador: INSTITUTO DE SALUD CARLOS III
Nº Expediente: CP17/00008
Ejecución: 2018-2022
IP: ANA MARÍA MÁRQUEZ ORTIZ
Título del proyecto: Identificación de Factores Genéticos de Riesgo Compartidos Entre Enfermedades Reumáticas Mediante Una Estrategia Meta-Immunochip
Financiador: CONSEJERIA DE SALUD
Nº Expediente: PI-0493-2016
Ejecución: 2017-2019
IP: RAQUEL RIOS FERNANDEZ
Título del proyecto: Lydimed: Lupus y Dieta Mediterránea
Financiador: CONSEJERÍA DE SALUD Y FAMILIAS
Nº Expediente: PI-0523-2016
Ejecución: 2017-2019
IP: NORBERTO ORTEGO CENTENO
Título del proyecto: Identificación de Factores Genéticos Implicados en el Desarrollo de Úlceras Digitales en Pacientes de Esclerodermia Mediante Un Estudio de Asociación del Genoma Completo (Gwas)
Financiador: FUNDACION PUBLICA ANDALUZA PROGRESO Y SALUD
Nº Expediente: PI-0390-2014
Ejecución: 2015-2017
IP: ANA MARÍA MÁRQUEZ ORTIZ
Título del proyecto: Detección Precoz de Osteoporosis: Identificación de Factores Genéticos Implicados en la Mineralización Ósea en Adultos Jóvenes
Financiador: FUNDACION PUBLICA ANDALUZA PROGRESO Y SALUD
Nº Expediente: PI-0414-2014
Ejecución: 2015-2017
IP: BLANCA Mª RUEDA MEDINA
Título del proyecto: PRECISESADS - Molecular Reclassification to Find Clinically Useful Biomarkers for Systemic Autoimmune Diseases
Financiador: COMISIÓN EUROPEA
Nº Expediente: PRECISESADS 115565 NOC
Ejecución: 2014-2019
IP: NORBERTO ORTEGO CENTENO
Título del proyecto: PRECISESADS - Molecular Reclassification to Find Clinically Useful Biomarkers for Systemic Autoimmune Diseases
Financiador: COMISIÓN EUROPEA
Nº Expediente: 115565
Ejecución: 2014-2019
IP: MARTA ALARCON RIQUELME
Título del proyecto: Identificación de Biomarcadores Genéticos de Los Diferentes Fenotipos de la Esclerosis Sistémica Mediante Un Estudio Amplio del Genoma (Gwas).
Financiador: CONSEJERÍA DE IGUALDAD, SALUD Y POLÍTICAS SOCIALES
Nº Expediente: PI-0590-2010
Ejecución: 2011-2013
IP: NORBERTO ORTEGO
Título del proyecto: Análisis de las variantes genética del gen de la endotelina y sus receptores en relación a la Esclerosis Sistémica y sus manifestaciones clínicas., con especial atención a la hipertensión pulmonar
Financiador: CONSEJERÍA DE IGUALDAD, SALUD Y POLÍTICAS SOCIALES
Nº Expediente: IBS-PI0136/07
Ejecución: 2008-2009
IP: NORBERTO ORTEGO
Título del ensayo: "Efecto de la medicación antihipertensiva en la gravedad de la anafilaxia y efectos secundarios durante la inmunoterapia a veneno de insectos himenópteros. EADOAS".
Tipo de ensayo: ESTUDIO POSAUTORIZACION INDEPENDIENTE
Financiador: EUROPEAN ACADEMY OF ALLERGY AND CLINICAL IMMUNOLOGY
Nº Expediente: 2739
Ejecución: 2015-2019
IP: CARMEN MORENO AGUILAR
Título del ensayo: Ensayo de fase III, abierto y multicéntrico de avelumab (MSB0010718C) frente a docetaxel en sujetos con carcinoma pulmonar no microcítico que ha progresado tras un doblete con platino
Tipo de ensayo: ENSAYO CLINICO COMERCIAL
Financiador: MERCK, S.L.U.
Nº Expediente: 2014-005060-15
Ejecución: 2015-2021
IP: AMPARO SANCHEZ GASTALDO
