Buscador de Publicaciones

(+)-Methyl (1R,2S)-2-{[4-(4-Chlorophenyl)-4-hydroxypiperidin-1-yl]methyl}-1-phenylcyclopropanecarboxylate [(+)-MR200] Derivatives as Potent and Selective Sigma Receptor Ligands: Stereochemistry and Pharmacological Properties

Autores: Amata, E; Rescifina, A; Prezzavento, O; Arena, E; Dichiara, M; Pittala, V; Montilla-Garcia, A; Punzo, F; Merino, P; Cobos, EJ; Marrazzo, A

Contilisant, a Tetratarget Small Molecule for Alzheimer’s Disease Therapy Combining Cholinesterase, Monoamine Oxidase Inhibition, and H3R Antagonism with S1R Agonism Profile

Autores: Bautista-Aguilera, OM; Budni, J; Mina, F; Medeiros, EB; Deuther-Conrad, W; Entrena, JM; Moraleda, I; Iriepa, I; Lopez-Munoz, F; Marco-Contelles, J

Synthesis, Receptor Affinity, and Antiallodynic Activity of Spirocyclic sigma Receptor Ligands with Exocyclic Amino Moiety

Autores: Bergkemper, M; Kronenberg, E; Thum, S; Borgel, F; Daniliuc, C; Schepmann, D; Nieto, FR; Brust, P; Reinoso, RF; Alvarez, I; Wunsch, B

Mechanistic Differences in Neuropathic Pain Modalities Revealed by Correlating Behavior with Global Expression Profiling

Autores: Cobos, EJ; Nickerson, CA; Gao, FY; Chandran, V; Bravo-Caparros, I; Gonzalez-Cano, R; Riva, P; Andrews, NA; Latremoliere, A; Seehus, CR; Perazzoli, G; Nieto, FR; Joller, N; Painter, MW; Ma, CHE; Omura, T; Chesler, EJ; Geschwind, DH; Coppola, G; Rangachari, M; Woolf, CJ; Costigan, M

Modality-specific peripheral antinociceptive effects of mu-opioid agonists on heat and mechanical stimuli: Contribution of sigma-1 receptors

Autores: Montilla-Garcia, A; Perazzoli, G; Tejada, MA; Gonzalez-Cano, R; Sanchez-Fernandez, C; Cobos, EJ; Baeyens, JM

Tetrahydro-3-benzazepines with fluorinated side chains as NMDA and sigma(1) receptor antagonists: Synthesis, receptor affinity, selectivity and antiallodynic activity

Autores: Thum, S; Schepmann, D; Ayet, E; Pujol, M; Nieto, FR; Ametamey, SM; Wunsch, B

A novel nanoformulation of PLGA with high non-ionic surfactant content improves in vitro and in vivo PTX activity against lung cancer

Autores: Jimenez-Lopez, J; El-Hammadi, MM; Ortiz, R; Cayero-Otero, MD; Cabeza, L; Perazzoli, G; Martin-Banderas, L; Baeyens, JM; Prados, J; Melguizo, C

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