Biobank and Disease Registry Platform
The Biobanco Platform includes 3 nodes located at the Virgen de las Nieves and San Cecilio University Hospitals, and the Cancer Registry at the EASP.
- HUCSC Biobank. RETICS
- HUVN Biobank. RETICS
- Granada Cancer Registry. EASP
Biobanks manage the healthcare use of samples from tissue banks and blood transfusion centers, as well as sample collections, their treatment and data for Biomedical Research.
Both the HUCSC Biobank and the HUVN Biobank are part of the Granada Provincial Node of the Andalusian Public Health System Biobank (https://biobanco.csalud.junta-andalucia.es/salud/biobanco/es), Biobank online, which constitutes a platform to support research specialized in obtaining, processing and storing human biological samples and their associated data, to make them available to the scientific community, thus providing a public service meeting the needs of researchers.
It is integrated into the National Biobank Network Platform, which is an initiative of the Institute of Health Carlos III with the aim of providing added value to the National Health System, favoring the development and quality of scientific production.
The activity of IBS GRANADA Disease Registry focuses on the Provincial Cancer Registry. It is a population-based registry that carries out continuous and systematic work to collect, analyze and interpret data from patients diagnosed with cancer in the province of Granada. It includes information on patient characteristics, clinical and pathological data of the tumor, as well as follow-up data. The information in the Registry is available for use by researchers at the Institute.
The biobank is present in both hospitals. In the Virgen de las Nieves University Hospital, it is located in the Clinical Analysis UGC, located on the ground floor of the Surgical Medical Hospital (HMQ) and on the 4th floor of the Government Building.
At the San Cecilio Clinical University Hospital (PTS), the biobank is located in the laboratory of the UGC for Clinical Analysis and in the Provincial Inter-Center Unit of Pathological Anatomy of the province of Granada (UPIGAP).
In the Andalusian School of Public Health there is the IBS GRANADA Disease Registry.
The Biobank has a wide and versatile portfolio of services, adjustable to the needs of each research project. The portfolio goes beyond the provision of samples in the strict sense. As a networked Biobank, we have organized a resource platform among all units to be able to offer samples and associated data in the format specified by the researcher, as well as sample processing and preservation services provided by the researcher.
Our portfolio of services is based on five pillars: provision, processing, preservation and custody of samples, advice and training.
If the bio-resources presented do not meet the researchers' needs, the Biobank offers personalized services.
- Collection and registration of samples and data for the availability of collections of samples and associated data corresponding to: healthy donors, patients with lymphoma, myeloma, hepatitis, diabetes, etc.
- Stabilization and Treatment of Biological Samples of diverse type, nature and format: tissue, blood, cells, saliva, plasma, serum, etc.
- Histological, cytological and phenotypic characterization by means of different stains and immunohistochemistry for numerous markers, of samples of different nature and derived from animal experimentation processes.
- Digitization of histological and cytological preparations, and digital analysis, for the evaluation of various preparations and stains.
- Molecular characterization based on PCR and FISH, and Quality Control of DNA, RNA and cell lines.
- Cytogenetic characterization by conventional and spectral karyotype (SKY).
- Cell cultures for the generation of tumor and normal cell lines of different origin, mesenchymal cord and fat, etc. that make up the Biobank catalog.
- Automated extraction of DNA and RNA from different biological samples and aliquoted from liquid samples.
- Distribution of the biological samples requested.
- Treatment and management of the necessary documentation.
La service portfolio borrowed is the following:
- DNA extraction.
- RNA extraction.
- Cryostat sections.
- Cell line culture.
- Immunohistochemistry.
- Microdissection.
- Sequencing.
- Study of microsatellite markers.
- Microsatellite instability study.
- Polymerase chain reaction (PCR).
- Quantitative real-time PCR.
- Flow cytometry.
