Biobank Platform and Disease Registry Platform
The Biobank Platform includes two nodes located at the Virgen de las Nieves and San Cecilio University Hospitals.
Biobanks manage the healthcare use of samples from tissue banks and blood transfusion centers, as well as sample collections, their treatment and data for Biomedical Research.
Both the HUCSC Biobank and the HUVN Biobank are part of the Granada Provincial Node of the Biobank of the Andalusian Public Health System , which form a networked Biobank, constituting a research support platform specializing in the collection, processing, and storage of human biological samples and their associated data, to make them available to the scientific community, thus providing a public service that meets the needs of researchers.
This regional network is part of the National Biobank Network Platform, an initiative of the Carlos III Health Institute, which was created with the aim of providing added value to the National Health System, promoting the development and quality of scientific production.
On the other hand, the Disease Registry Platform is an activity of ibs.GRANADA that focuses on the Provincial Cancer RegistryThis is a population-based registry that continuously and systematically collects, analyzes, and interprets data on cancer patients diagnosed in the province of Granada. It includes information on patient characteristics, clinical and pathological data on the tumor, as well as follow-up data. The Registry's information is available for use by the Institute's researchers.
The biobank is present in both hospitals. In the Virgen de las Nieves University Hospital, it is located in the Clinical Analysis UGC, located on the ground floor of the Surgical Medical Hospital (HMQ) and on the 4th floor of the Government Building.
At the San Cecilio Clinical University Hospital (PTS), the biobank is located in the laboratory of the UGC for Clinical Analysis and in the Provincial Inter-Center Unit of Pathological Anatomy of the province of Granada (UPIGAP).
In the Andalusian School of Public Health there is the IBS GRANADA Disease Registry.
The Biobank has a wide and versatile portfolio of services, adjustable to the needs of each research project. The portfolio goes beyond the provision of samples in the strict sense. As a networked Biobank, we have organized a resource platform among all units to be able to offer samples and associated data in the format specified by the researcher, as well as sample processing and preservation services provided by the researcher.
Our portfolio of services is based on five pillars: provision, processing, preservation and custody of samples, advice and training.
If the bio-resources presented do not meet the researchers' needs, the Biobank offers personalized services.
- Collection and registration of samples and data for the availability of collections of samples and associated data corresponding to: healthy donors, patients with lymphoma, myeloma, hepatitis, diabetes, etc.
- Stabilization and Treatment of Biological Samples of diverse type, nature and format: tissue, blood, cells, saliva, plasma, serum, etc.
- Histological, cytological and phenotypic characterization by means of different stains and immunohistochemistry for numerous markers, of samples of different nature and derived from animal experimentation processes.
- Digitization of histological and cytological preparations, and digital analysis, for the evaluation of various preparations and stains.
- Molecular characterization based on PCR and FISH, and Quality Control of DNA, RNA and cell lines.
- Cytogenetic characterization by conventional and spectral karyotype (SKY).
- Cell cultures for the generation of tumor and normal cell lines of different origin, mesenchymal cord and fat, etc. that make up the Biobank catalog.
- Automated extraction of DNA and RNA from different biological samples and aliquoted from liquid samples.
- Distribution of the biological samples requested.
- Treatment and management of the necessary documentation.
La service portfolio borrowed is the following:
- DNA extraction.
- RNA extraction.
- Cryostat sections.
- Cell line culture.
- Immunohistochemistry.
- Microdissection.
- Sequencing.
- Study of microsatellite markers.
- Microsatellite instability study.
- Polymerase chain reaction (PCR).
- Quantitative real-time PCR.
- Flow cytometry.
