Investigation area: Precision Medicine

The area of ​​Precision Medicine is characterized by its marked translational character, in short, by the need to facilitate the transition from basic research into clinical applications that benefit health. This area arose as a need to address the challenge of "personalized medicine" that refers to the adaptation of medical interventions to the individual characteristics of each patient. It is the largest area of ​​the institute including various medical specialties and disciplines involved in translational research for the treatment of diseases.

The objectives of the area are:

a) Define the genetic bases in complex, chronic non-communicable diseases and rare diseases by generating phenotypic data associated with genome, transcriptome, proteome, metabolome, microbiome and exposome data.

b) Study biomarkers of exposure, diagnosis and therapeutic response in complex, chronic non-communicable and rare diseases.

c) Investigate the mechanisms of rare, complex and communicable diseases for the development and evaluation of new therapies: pharmacological (translational studies and clinical trials in different chronic diseases), surgical (Parkinson's disease, tremor, dystonia, epilepsy, hydrocephalus), physical (physiotherapy, mechanical ventilation), endovascular (arrhythmia ablation, cardiac hemodynamics), nutritional and lifestyle, including social and / or psychological aspects (systemic autoimmune diseases, obesity, diabetes, neurodevelopmental and behavioral disorders ...) , as well as healthcare needs and satisfaction with the care received.

Line: Diagnosis based on omic data.

Line B: Biomarkers for clinical diagnosis.

Line C: Mechanisms of disease and development of new therapies.