TEC15-Nuclear and Molecular Medicine

Information
Members
Publications
Projects
Clinical trials

The group has been developing its research in the identification of new tracers applicable to the diagnosis and evaluation of the pharmacological response of cancer. It belongs to the CANCER Corporate Research Thematic Network and is a benchmark in the technical evaluation of new useful procedures in Nuclear Medicine. Diagnostic imaging platform.

Research lines

Clinical applications of PET. Incidence of the technique in clinical decision-making in the field of oncology.
Nuclear endocrinology. Applications of isotopes to the study of endocrinological processes. Genetic markers in thyroid cancer.
Neurology, Neuropsychology and Nuclear Psychiatry. Applications of isotopes to the study of the CNS (dementias, CNS tumors, neurological involvement of systemic processes, etc.).
Radiopharmacy Marking, galenic development and quality control of new radiopharmaceuticals.

Keywords

Radiopharmaceuticals, Diagnostic Imaging, Nuclear Medicine.

MARIA ELISA MERCHAN RAMIREZ

ORCID

Ana Cristina Villena Garcia

Maria Emiliana Bellon Guardia

GUILLERMO SANCHEZ DELGADO

ORCID

IRENE ESTEBAN-CORNEJO

TARIK AROUI LUQUIN

YOLANDA RIBERO GARCIA

JAVIER RAMIREZ PEREZ DE INESTROSA

IGNACIO ALVAREZ ILLAN

MANUEL GOMEZ RIVERS

JUAN MANUEL GORRIZ SAEZ

MARIA ANGUSTIAS WALLS OF FOUNTAINS

Jurado-Fasoli, L; Sanchez-Delgado, G; Alcantara, JMA; Acosta, F.M.; Sanchez-Sanchez, R; Labayen, I; Ortega, F.B.; Martinez-Tellez, B; Ruiz, J.R.

Adults with metabolically healthy overweight or obesity present more brown adipose tissue and higher thermogenesis than their metabolically unhealthy counterparts

EBIOMEDICINE, 2024;

FI: 9,7; D1

Jurado-Fasoli, L; Sanchez-Delgado, G; Say, XY; Yang, W; Kohler, I; Villarroya, F; Aguilera, CM; Hankemeier, T; Ruiz, JR; Martinez-Tellez, B

Cold-induced changes in plasma signaling lipids are associated with a healthier cardiometabolic profile independently of brown adipose tissue

CELL REPORTS MEDICINE, 2024;

FI: 11,7; D1

Rodriguez-Ayllo, M; Solis-Urra, P; Arroyo-Avila, C; Alvarez-Ortega, M; Molina-García, P; Molina-Hidalgo, C; Gómez-Río, M; Brown, B; Erickson, KI; Esteban-Cornejo, I

Physical activity and amyloid beta in middle-aged and older adults: A systematic review and meta-analysis

JOURNAL OF SPORT AND HEALTH SCIENCE, 2024;

FI: 9,7; D1

Esteban-Cornejo, I; Lara-Jimenez, I; Rodriguez-Ayllon, M; Verdejo-Roman, J; Catena, A; Erickson, KI; Ortega, FB

Early morning physical activity is associated with healthier white matter microstructure and happier children: the ActiveBrains project

EUROPEAN CHILD & ADOLESCENT PSYCHIATRY, 2024;

FI: 6; D1

Deng, LJ; Zhou, QH; Wang, SH; Górriz, JM; Zhang, YD

Deep learning in crowd counting: A survey

CAAI TRANSACTIONS ON INTELLIGENCE TECHNOLOGY, 2024;

FI: 8,4; D1

Rudolphi-Solero, T; Trivino-Ibanez, EM; Martinez-Barbero, JP; Cordero-Tous, N; Chamorro-Santos, CE; Rodriguez-Fernandez, A; Gomez-Rio, MM

[18F]Fluorocholine PET/CT false positive: foreign body reaction mimicking anaplastic glioma progression. A case report

EGYPTIAN JOURNAL OF NEUROLOGY PSYCHIATRY AND NEUROSURGERY, 2023;

Mendez-Gutierrez, A; Aguilera, CM; Osuna-Prieto, FJ; Martinez-Tellez, B; Prados, MCR; Acosta, FM; Llamas-Elvira, JM; Ruiz, JR; Sanchez-Delgado, G

Exercise-induced changes on exerkins that might influence brown adipose tissue metabolism in young sedentary adults

EUROPEAN JOURNAL OF SPORT SCIENCE, 2023;

FI: 3,2; Q2

Solis-Urra, P; Molina-Hidalgo, C; Garcia-Rivero, Y; Costa-Rodriguez, C; Mora-Gonzalez, J; Fernandez-Gamez, B; Olvera-Rojas, M; Coca-Pulido, A; Toval, A; Bellon, D; Sclafani, A; Martin-Fuentes, I; Trivino-Ibanez, EM; de Teresa, C; Huang, HQ; Grove, G; Hill

Active Gains in brain Using Exercise During Aging (AGUEDA): protocol for a randomized controlled trial

FRONTIERS IN HUMAN NEUROSCIENCE, 2023;

FI: 2,9; Q3

Mogollón-González, M; Conde-Muiño, R; Rodríguez-Fernández, A; Navarro-Pelayo, M; Domínguez-Basante, M; Palma, P.

Impact of routine preoperative 18FDG PET/CT on the surgical management of primary colorectal cancer

JOURNAL OF SURGICAL ONCOLOGY, 2023;

FI: 2,5; Q4

Rudolphi-Solero, T; Rashki, M; Fernández-Fernández, J; Rivas-Navas, D; Ramos-Font, C; Rodríguez-Fernández, A

SARS-COV-2 virus triggers immune antitumor response in a lymphoma patient

SPANISH JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGE, 2023;

FI: 1,2; Q4

Rudolphi-Solero, T; Ibanez, EMT; Aroui, T; Christmas, RH; Gomez-Rio, M

Dual-Phase F-18-Florbetaben PET/CT Unsuspected Thalamic Infarction Mimicking Alzheimer Disease

CLINICAL NUCLEAR MEDICINE, 2022;

FI: 10,782; D1

Schonecker, S; Martinez-Murcia, FJ; Rauchmann, B.S.; Franzmeier, N; Prix, C; Wlasich, E; Loosli, SV; Bochmann, K; Saez, JMG; Laforce, R; Ducharme, S; Tartaglia, MC; Finger, E; de Mendonca, A; Santana, I; Sanchez-Valle, R; Moreno, F; Sorbi, S; Tagliavini, F; Borroni, B; Otto, M; Synofzik, M; Galimberti, D; Vandenberghe, R; van Swieten, J; Butler, C; Gerhard, A; Graff, C; Danek, A; Rohrer, J.D.; Masellis, M; Rowe, J; Levin, J.

Frequency and Longitudinal Course of Motor Signs in Genetic Frontotemporal Dementia

NEUROLOGY, 2022;

FI: 11,8; D1

Rudolphi-Solero, T; Lorenzo-Alvarez, R; Ruiz-Gomez, MJ; Sendra-Portero, F

Impact of compulsory participation of medical students in a multiuser online game to learn radiological anatomy and radiological signs within the virtual world Second Life

ANATOMICAL SCIENCES EDUCATION, 2022;

FI: 6,652; D1

Martinez-Tellez, B; Sanchez-Delgado, G; Acosta, FM; Alcantara, JMA; Amaro-Gahete, FJ; Martinez-Avila, WD; Merchan-Ramirez, E; Munoz-Hernandez, V; Osuna-Prieto, FJ; Jurado-Fasoli, L; Xu, H.W. Ortiz-Alvarez, L; Arias-Tellez, MJ; Mendez-Gutierrez, A; Labayen, I; Ortega, FB; Schonke, M; Rensen, PCN; Aguilera, CM; Llamas-Elvira, JM; Gil, A; Ruiz, JR

No evidence of brown adipose tissue activation after 24 weeks of supervised exercise training in young sedentary adults in the ACTIBATE randomized controlled trial

NATURE COMMUNICATIONS, 2022;

FI: 17,694; D1

Gorriz, JM; Jimenez-Mesa, C; Segovia, F; Ramirez, J; Suckling, J.

A Connection Between Pattern Classification by Machine Learning and Statistical Inference With the General Linear Model

IEEE JOURNAL OF BIOMEDICAL AND HEALTH INFORMATICS, 2022;

FI: 7,021; Q1

Jurado-Fasoli, L; Merchan-Ramirez, E; Martinez-Tellez, B; Acosta, FM; Sanchez-Delgado, G; Amaro-Gahete, FJ; Hernandez, VM; Martinez-Avila, W.D.; Ortiz-Alvarez, L; Xu, HW; Tellez, MJA; Ruiz-Lopez, MD; Llamas-Elvira, JM; Gil, A; Labayen, I; Ruiz, J.R.

Association between dietary factors and brown adipose tissue volume/F-18-FDG uptake in young adults

CLINICAL NUTRITION, 2021;

FI: 7,325; D1

Sanchez-Delgado, G; Martinez-Tellez, B; Acosta, FM; Virtue, S; Vidal-Puig, A; Gil, A; Llamas-Elvira, JM; Ruiz, J.R.

Brown Adipose Tissue Volume and Fat Content Are Positively Associated With Whole-Body Adiposity in Young Men-Not in Women

DIABETES, 2021;

FI: 9,461; D1

Arch, JE; Ramirez, J.; Gorriz, JM; Ruz, M.

Data fusion based on Searchlight analysis for the prediction of Alzheimer's disease

EXPERT SYSTEMS WITH APPLICATIONS, 2021;

FI: 6,954; D1

Rudolphi-Solero, T; Jiménez-Zayas, A; Lorenzo-Alvarez, R; Dominguez-Pinos, D; Ruiz-Gomez, MJ; Sendra-Portero, F

A team-based competition for undergraduate medical students to learn radiology within the virtual world Second Life

INSIGHTS INTO IMAGING, 2021;

FI: 5,231; Q1

Romero-Garcia, R; Hart, MG; Bethlehem, RAI; Mandal, A; Asem, M; Crespo-Facorro, B; Gorriz, JM; Burke, GAA; Price, S.J.; Santarius, T.; Erez, Y; Suckling, J.

BOLD Coupling between Lesioned and Healthy Brain Is Associated with Glioma Patients' Recovery

CANCER, 2021;

FI: 6,639; Q1

Castillo-Barnes, D; His, L; Ramirez, J; Salas-Gonzalez, D; Martinez-Murcia, FJ; Illan, IA; Segovia, F; Ortiz, A; Cruchaga, C; Farlow, MR; Xiong, CJ; Graff-Radford, NR; Schofield, PR; Masters, CL; Salloway, S; Jucker, M; Mori, H; Levin, J; Gorriz, JM

Autosomal dominantly inherited Alzheimer disease: Analysis of genetic subgroups by machine learning

INFORMATION FUSION, 2020;

FI: 13,669; D1

Sanchez-Delgado, G; Acosta, FM; Martinez-Tellez, B; Finlayson, G; Gibbons, C; Labayen, I; Llamas-Elvira, JM; Gil, A; Blundell, J.E.; Ruiz, Jr.

Brown adipose tissue volume and F-18-fluorodeoxyglucose uptake are not associated with energy intake in young human adults.

AMERICAN JOURNAL OF CLINICAL NUTRITION, 2020;

FI: 6,766; D1

Porras, I; Praena, J; from Saavedra, FA; Pedrosa-Rivera, M; Torres-Sanchez, P; Sabariego, MP; Exposito-Hernandez, J; Llamas-Elvira, JM; Ramirez-Navarro, A; Rodriguez-Fernandez, A; Osorio-Ceballos, JM; Ruiz-Ruiz, C; Ruiz-Magana, MJ

BNCT research activities at the Granada group and the project NeMeSis: Neutrons for medicine and sciences, towards an accelerator-based facility for new BNCT therapies, medical isotope production and other scientific neutron applications

APPLIED RADIATION AND ISOTOPES, 2020;

FI: 1,27; Q2

Martinez-Tellez, B; Sanchez-Delgado, G; Boon, M.R.; Rensen, PCN; Llamas-Elvira, JM; Ruiz, Jr.

Distribution of Brown Adipose Tissue Radiodensity in Young Adults: Implications for Cold [F-18] FDG-PET / CT Analyzes

MOLECULAR IMAGING AND BIOLOGY, 2020;

FI: 2,925; Q2

Jimenez, ADG; Fernandez, AR; Sanchez, RS; Eagle, FJ; Garcia, JDM; Elvira, JML

False positive in fluorodeoxyglucose-F18 positron emission tomography computed tomography scan of inferior vena cava leiomyoma in patient with a suspected paraganglioma

SPANISH JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGE, 2020;

FI: 1,09; Q4

Ortiz, A; Munilla, J; Martinez-Murcia, FJ; Gorriz, JM; Ramirez, J.

Empirical Functional PCA for 3D Image Feature Extraction Through Fractal Sampling

INTERNATIONAL JOURNAL OF NEURAL SYSTEMS, 2019;

FI: 6,4; D1

Ortiz, A; Murcia, FJM; Munilla, J; Gorriz, JM; Ramirez, J.

Label aided deep ranking for the automatic diagnosis of Parkinsonian syndromes

NEUROCOMPUTING, 2019;

FI: 4,072; Q1

Ramos-Font, C; Jiménez-Heffernan, A; Jimenez, AG; Rashki, M; Elvira, JML

Regadenoson long-lasting use induced tachyarrythmia

JOURNAL OF NUCLEAR CARDIOLOGY, 2019;

FI: 4,112; Q1

Acosta, FM; Martinez-Tellez, B; Sanchez-Delgado, G; Migueles, JH; Contreras-Gomez, MA; Martinez-Avila, W.D.; Merchan-Ramirez, E; Alcantara, JMA; Amaro-Gahete, FJ; Llamas-Elvira, JM; Ruiz, Jr.

Association of Objectively Measured Physical Activity With Brown Adipose Tissue Volume and Activity in Young Adults

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2019;

FI: 5,605; Q1

Acosta, FM; Sanchez-Delgado, G; Martinez-Tellez, B; Migueles, JH; Amaro-Gahete, FJ; Rensen, PCN; Llamas-Elvira, JM; Blondin, DP; Ruiz, Jr.

Sleep duration and quality are not associated with brown adipose tissue volume or activity-as determined by F-18-FDG uptake, in young, sedentary adults

SLEEP, 2019;

FI: 4,571; Q1

Martinez-Tellez, B; Nahon, KJ; Sanchez-Delgado, G; Abreu-Vieira, G; Llamas-Elvira, JM; van Velden, FHP; Arias-Bouda, LMP; Rensen, PCN; Boon, M.R.; Ruiz, Jr.

The impact of using BARCIST 1.0 criteria on quantification of BAT volume and activity in three independent cohorts of adults

SCIENTIFIC REPORTS, 2018;

FI: 4,122; Q1

Segovia, F; Sanchez-Vano, R; Gorriz, JM; Ramirez, J; Sopena-Novales, P; Dardel, N.T.; Rodriguez-Fernandez, A; Gomez-Rio, M

Using CT Data to Improve the Quantitative Analysis of F-18-FBB PET Neuroimaging

FRONTIERS IN AGING NEUROSCIENCE, 2018;

FI: 3,582; Q1

Sanchez-Delgado, G; Martinez-Tellez, B; Garcia-Rivero, Y; Alcantara, JMA; Acosta, FM; Amaro-Gahete, FJ; Llamas-Elvira, JM; Ruiz, Jr.

Brown Adipose Tissue and Skeletal Muscle F-18-FDG Activity After a Personalized Cold Exposure Is Not Associated With Cold-Induced Thermogenesis and Nutrient Oxidation Rates in Young Healthy Adults

FRONTIERS IN PHYSIOLOGY, 2018;

FI: 3,394; Q1

Martinez-Tellez, R; Xu, H. W.; Sanchez-Delgado, G; Acosta, FM; Rensen, PCN; Llamas-Elvira, JM; Ruiz, Jr.

Association of wrist and ambient temperature with cold-induced brown adipose tissue and skeletal muscle [F-18] FDG uptake in young adults

AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY, 2018;

FI: 3,082; Q2

Segovia, F; Gomez-Rio, M; Sanchez-Vano, R; Gorriz, JM; Ramirez, J; Trivino-Ibanez, E; Carnero-Pardo, C; Martinez-Lozano, MD; Sopena-Novales, P.

Usefulness of Dual-Point Amyloid PET Scans in Appropriate Use Criteria: A Multicenter Study

JOURNAL OF ALZHEIMERS DISEASE, 2018;

FI: 3,476; Q2

Martinez-Tellez, B; Sanchez-Delgado, G; Garcia-Rivero, Y; Alcantara, JMA; Martinez-Avila, W.D.; Munoz-Hernandez, M.V.; Olza, J; Boon, M.R.; Rensen, PCN; Llamas-Elvira, JM; Ruiz, Jr.

A New Personalized Cooling Protocol to Activate Brown Adipose Tissue in Young Adults

FRONTIERS IN PHYSIOLOGY, 2017;

FI: 4,134; Q1

Bayarri-Lara, CI; Perez, D.D.; deGuevara, ACL; Fernandez, AR; Puche, JL; Ramos, ASP; Zafra, JR; Ospina, CFG; Delgado-Rodriguez, M; Ruiz, ME; Rodriguez, MJM; Lorente, JA; Serrano, MJ

Association of circulating tumor cells with early relapse and F-18-fluorodeoxyglucose positron emission tomography uptake in resected non-small-cell lung cancers

EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY, 2017;

FI: 3,759; Q1

Varela-Lopez, A; Ochoa, JJ; Llamas-Elvira, JM; Lopez-Frias, M; Planells, E; Ramirez-Tortosa, M; Ramirez-Tortosa, CL; Giamperi, F; Battino, M; Quiles, JL

Age-Related Loss in Bone Mineral Density of Rats Fed Lifelong on a Fish Oil-Based Diet Is Avoided by Coenzyme Q (10) Addition

NUTRIENTS, 2017;

FI: 3,55; Q2

Varela-Lopez, A; Ochoa, JJ; Llamas-Elvira, JM; Lopez-Frias, M; Planells, E; Hope, L; Battino, M; Quiles, JL

Loss of Bone Mineral Density Associated with Age in Male Rats Fed on Sunflower Oil Is Avoided by Virgin Olive Oil Intake or Coenzyme Q Supplementation

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2017;

FI: 3,226; Q2

Vallejo, J.A.; Walls, MA

Cost-effectiveness of using recombinant human thyroid-stimulating hormone before radioiodine ablation for thyroid cancer treatment in Spanish hospitals.

SPANISH JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGE, 2017;

FI: 0,951; Q4

Canadas-Garre, M; Becerra-Massare, P; Casares, AM; Calleja-Hernandez, MA; Llamas-Elvira, JM

Relevance of BRAF and NRAS mutations in the primary tumor and metastases of papillary thyroid carcinomas.

HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, 2016;

FI: 2,76; D1

Ibanez, EMT; Walls, MA; Candle, E.T.; Elvira, JML

The role of early 18F-FDG PET / CT in therapeutic management and ongoing risk stratification of high / intermediate-risk thyroid carcinoma

ENDOCRINE, 2016;

FI: 3,279; Q2

Gomez-Rio, M; Knight, MM; Saez, JMG; Minguez-Castellanos, A

Diagnosis of Neurodegenerative Diseases: The Clinical Approach

CURRENT ALZHEIMER RESEARCH, 2016;

FI: 3,145; Q2

Martin, M.J.A.; Navarro, AMG; Fernandez, AR; Rios, haha

Oesophageal leiomyoma with intense uptake in positron tomography with (18) Fluorodeoxyglucose and computed tomography

ESPANOL SURGERY, 2016;

FI: 1; Q3

Navarro-Pelayo, M.M.; Rodriguez-Fernandez, A; Ramirez-Navarro, A; Martin-Castro, A; Gomez-Rio, M; Llamas-Elvira, JM

Hibernoma as an incidental finding on F-18-FDG-PET / CT in lymphoma patient follow-up

SPANISH JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGE, 2016;

FI: 0,983; Q4

Gomez-Rio, M; Dardel, N.T.; Chinchilla, AS; Rodriguez-Fernandez, A; Granados, GO; Caro, R.L.; Herrera, MZ; Santos, CEC; Lardelli-Claret, P; Llamas-Elvira, JM

F-18-Fluorocholine PET / CT as a complementary tool in the follow-up of low-grade glioma: diagnostic accuracy and clinical utility

EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2015;

FI: 5,383; D1

Rodado-Marina, S; Coronado-Poggio, M; Garcia-Vicente, AM; Garcia-Garzon, JR; Alonso-Farto, JC; de la Jara, AC; Maldonado-Suarez, A; Rodriguez-Fernandez, A.

Clinical utility of F-18-fluorocholine positron-emission tomography / computed tomography (PET / CT) in biochemical relapse of prostate cancer after radical treatment: results of a multicentre study

BJU INTERNATIONAL, 2015;

FI: 3,533; Q1

Sanchez-Delgado, G; Martinez-Tellez, B; Olza, J; Aguilera, C.M.; Labayen, I; Ortega, F.B.; Chillon, P; Fernandez-Reguera, C; Alcantara, JMA; Martinez-Avila, W.D.; Munoz-Hernandez, V; Acosta, FM; Prados-Ruiza, J; Amaro-Gallete, FJ; Hidalgo-Garcia, L; Rodriguez, L; Ruiz, Y.A.K.; Ramirez-Navarro, A; Walls-de Fuentes, MA; Garcia-Rivero, Y; Sanchez-Sanchez, R; Jimenez, JDB; de Theresa, C; Navarrete, S; Lozano, R; Brea-Gomez, E; Rubio-Lopez, J; Ruiz, M.R.; Cano-Nieto, A; Llamas-Elvira, JM; Rios, HAJ; Gil, A; Ruiz, Jr.