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MP23-Critical Pathology (Emerging)

Precision Medicine / IBS-MP23 / Emerging

ibs.GRANADA  ·  Research groups
  • Information
  • Members
  • Publications
  • Projects
  • Clinical trials

Critically ill patients present particularities both in the facet of their clinical care and in the performance of research studies. The seriousness of his situation forces in many cases to make decisions quickly and with the participation of third parties (family members or legal representatives). Caring for these patients requires the collaboration of multiple specialists and professional categories, who must also participate in research activities, contributing their points of view.

The group is made up of health professionals who are dedicated to the care of these patients. The multidisciplinary vision is guaranteed as both doctors and nurses are members of the group. Likewise, there is collaboration with other groups at the local, national and international level.

Research lines

  • Prevention of pressure injuries. COMHON assessment scale (patented by the group). Measurement package associated with the COMHON Scale (validation).
  • Patient safety. Implementation of security rounds. Attention to the second victims. Attention to caregivers.
  • Nosocomial infections in critically ill patients.
  • Microbiota and resistome in the critically ill patient.
  • Nutrition and metabolism in the critically ill patient.
  • Technology applied to acute cardiovascular disease. Devices in cardiogenic shock.
  • Nursing care of the critically ill patient.

Keywords

Intensive Care, Critical Medicine, Pulmonary Edema, Extra-Vascular Pulmonary Water, Traumatic Hemorrhage, Traumatic Coagulopathy.

RAIMUNDO GARCIA DEL MORAL MARTIN

  • ORCID

MARIA ESTHER RODRIGUEZ DELGADO

  • ORCID

ANGEL COBOS VARGAS

  • ORCID

MARIA EUGENIA YUSTE OSORIO

ANA MARIA ECHEVERRIA ALVAREZ

JOSE MANUEL SOTO WHITE

MANUEL COLMENERO RUIZ

  • More Information
  • ORCID

FRANCISCO LUIS MANZANO MANZANO

FRANCISCA PINO SANCHEZ

MANUEL MUÑOZ GARACH

  • ORCID
Garzon-Furne, AI; Ferreiro-Marzala, A; Rodriguez-Serrano, F; Esteban-Molina, M; Garcia-Orta, R; Moreno-Escobar, E; Garcia-Delgado, M; Sevilla-Martinez, M; Gomez-Luque, JM; Ocete-Hita, E; Rodríguez-Vázquez del Rey, MD; Nuila-Durán, LM; Garrido, J.M.

Valve repair in mitral endocarditis

CARDIOVASCULAR SURGERY, 2023;

Cobos-Vargas, A; Acosta-Romero, M; Alba-Fernández, C; Gutierrez-Linares, S; Rodriguez-Blanquez, R; Colmenero, M

Compliance with preventive measures recommended by an international study group for pressure injuries in adult critically ill patients

INTERNATIONAL WOUND JOURNAL, 2023;

FI: 3,1; Q2

Muñoz-Garach, M; Moreno-Romero, O; Ramirez-Puerta, R; Yuste-Ossorio, E; Quintana-Luque, F; Muñoz-Torres, M; Colmenero, M

Accuracy of Modified Blue-Dye Testing in Predicting Dysphagia in Tracheotomized Critically Ill Patients

DIAGNOSTICS, 2023;

FI: 3,6; Q2

Garcia-Garcia, J; Diez-Echave, P; Yuste, ME; Chueca, N; Garcia, F; Cabeza-Barrera, J; Fernandez-Varon, E; Galvez, J; Colmenero, M; Rodriguez-Cabezas, ME; Rodriguez-Nogales, A; Moron, R

Gut Microbiota Composition Can Predict Colonization by Multidrug-Resistant Bacteria in SARS-CoV-2 Patients in Intensive Care Unit: A Pilot Study

ANTIBIOTICS-BASEL, 2023;

FI: 4,8; Q2

Tejero-Aranguren, J; Aguilera, EP; Colmenero, M; del Moral, RG

A need for post-intensive care follow-up training

INTENSIVE MEDICINE, 2023;

FI: 3; Q3

Rodriguez-Delgado, E; del Moral, RG; Cobos-Vargas, A; Martin-Lopez, J; Colmenero, M

Agreement of blood glucose measured with glucose meter in arterial, central venous, and capillary samples in adult critically ill patients

NURSING IN CRITICAL CARE, 2022;

FI: 2,897; Q1

Martinez, MS; Saez, VC; Delgado, MJG

Endobronchial fibrinolysis in a patient with extracorporeal membrane oxygenation

INTENSIVE MEDICINE, 2022;

FI: 2,799; Q3

Nieto-Gomez, P; Romero, RM; del Pozo, E.P.; Cabeza-Barrera, J; Ruiz, MC

Evaluation of quality indicators for nutrition and metabolism in critically ill patients: role of the pharmacist

EUROPEAN JOURNAL OF HOSPITAL PHARMACY, 2021;

FI: 1,652; Q4

Cordovilla-Guardia, S; Ortega-Ortega, M; Epstein, D; Fernandez-Mondejar, E; Vilar-Lopez, R.

Economic Analysis of Brief Motivational Intervention Following Trauma Related to Drugs and Alcohol

NURSING RESEARCH, 2020;

FI: 1,881; Q1

Martin-Delgado, MC; Martinez-Soba, F; Masnou, N; Perez-Villares, JM; Pont, T; Carter, MJS; Velasco, J; Of the Street, B; Squire, D; Estebanez, B; Coll, E; Perez-Blanco, A; Perojo, L; Urunuela, D; Dominguez-Gil, B.

Summary of Spanish recommendations on intensive care to facilitate organization donation

AMERICAN JOURNAL OF TRANSPLANTATION, 2019;

FI: 7,163; D1

Martinez-Soba, F; Perez-Villares, JM; Martinez-Camarero, L; Lara, R; Monzon, JL; Fernandez-Carmona, A; Marco, P; Coll, E; Dominguez-Gil, B.

Intensive Care to Facilitate Organ Donation: A Report on the Experience of 2 Spanish Centers With a Common Protocol

TRANSPLANTATION, 2019;

FI: 4,743; D1

del Rio, F; Andres, A; Padilla, M; Sanchez-Fructuoso, AI; Molina, M; Ruiz, A; Perez-Villares, JM; Peiro, LZ; Aldabo, T; Sebastian, R; Minambres, E; Pita, L; Casares, M; Galan, J; Vidal, C; Terron, C; Castro, P; Sanroma, M; Coll, E; Dominguez-Gil, B; Atutxa, L; Delgado, MI; Egea-Guerrero, JJ; Carmona, AF; Rodriguez, AF; Garcia, AF; Gallego, E; de Gracia, C; Mancino, JM; Marquez, MA; Oliver, E; Pont, T; Ruiz, JC; Vazquez, S; Shoemaker, A

Kidney transplantation from donors after uncontrolled circulatory death: the Spanish experience

KIDNEY INTERNATIONAL, 2019;

FI: 8,306; D1

de Haro, C; Magrans, R; Lopez-Aguilar, J; Montanya, J; Lena, E; Go up, C; Fernandez-Gonzalo, S; Gum, G; Fernandez, R; Albaiceta, GM; Skrobik, Y; Lucangelo, U; Murias, G; Ochagavia, A; Kacmarek, RM; Rue, M; Blanch, L; de Haro, C; Lopez-Aguilar, J; Magrans, R; Fernandez-Gonzalo, S; Gum, G; Chacon, E; Struga, A; Ochagavia, A; Blanch, L; Montanya, J; Sales, B; Lena, E; Lucangelo, U; Fernandez, R; Go up, C; Albaiceta, GM; Fernandez-Mondejar, E; Murias, G; Kacmarek, RM

Effects of sedatives and opioids on trigger and cycling asynchronies throughout mechanical ventilation: an observational study in a large dataset from critically ill patients.

CRITICAL CARE, 2019;

FI: 6,959; Q1

Cordovilla-Guardia, S; Lardelli-Claret, P; Vilar-Lopez, R; Lopez-Espuela, F; Guerrero-Lopez, F; Fernandez-Mondejar, E.

The effect of central nervous system depressant, stimulant and hallucinogenic drugs on injury severity in patients admitted for trauma

SANITARY GAZETTE, 2019;

FI: 1,656; Q2

Of the White, MAIP; Mondejar, E. F.; Jimenez, FJG; Morales, JMA; Lombard, M.D.Q.; Rodriguez, JLV

Risk factors for intracranial lesions and mortality in older patients with mild traumatic brain injuries.

BRAIN INJURY, 2018;

FI: 2,061; Q1

Cordovilla-Guardia, S; Garcia-Jimenez, C; Fernandez-Mondejar, E; Calderon-Garcia, JF; Lopez-Espuela, F; Franco-Antonio, C; Rico-Martin, S; Lardelli-Claret, P.

Association between the detection of alcohol, illicit drugs and / or psychotropic medications / opioids in patients admitted due to trauma and trauma recidivism: A cohort study

PLOSONE, 2018;

FI: 2,766; Q1

Rodriguez-Fernandez, S; Castillo-Lorente, E; Guerrero-Lopez, F; Rodriguez-Rubio, D; Aguilar-Alonso, E; Lafuente-Baraza, J; Gomez-Jimenez, FJ; Mora-Ordonez, J; Rivera-Lopez, R; Arias-Verdu, MD; Quesada-Garcia, G; Arraez-Sanchez, MA; Rivera-Fernandez, R.

Validation of the ICH score in patients with spontaneous intracerebral haemorrhage admitted to the intensive care unit in Southern Spain.

BMJ OPEN, 2018;

FI: 2,413; Q2

Cordovilla-Guardia, S; Vilar-Lopez, R; Lardelli-Claret, P; Guerrero-Lopez, F; Fernandez-Mondejar, E.

Alcohol or Drug Use and Trauma Recidivism

NURSING RESEARCH, 2017;

FI: 1,929; Q1

Cordovilla-Guardia, S; Fernandez-Mondejar, E; Vilar-Lopez, R; Navas, JF; Portillo-Santamaria, M; Rico-Martin, S; Lardelli-Claret, P.

Effect of a brief intervention for alcohol and illicit drug use on trauma recidivism in a cohort of trauma patients.

PLOSONE, 2017;

FI: 2,806; Q1

Llompart-Pou, J.A.; Chico-Fernandez, M; Sanchez-Casado, M; Salaberria-Udabe, R; Carbayo-Gorriz, C; Guerrero-Lopez, F; Gonzalez-Robledo, J; Ballesteros-Sanz, MA; Herran-Monge, R; Servia-Goixart, L; Leon-Lopez, R; Val-Jordan, E.

Scoring severity in trauma: comparison of prehospital scoring systems in trauma ICU patients.

EUROPEAN JOURNAL OF TRAUMA AND EMERGENCY SURGERY, 2017;

FI: 0,895; Q3

Rivera-Lopez, R; Gutierrez-Rodriguez, R; Lopez-Caler, C; Aguilar-Alonso, E; Castillo-Lorente, E; Garcia-Delgado, M; Arias-Verdu, MD; Iglesias-Posadilla, D; Barrueco-Francioni, J.E.; Quesada-Garcia, G; Rivera-Fernandez, R.

Relationship between functional status prior to onset of critical illness and mortality: a prospective multicenter cohort study

ANESTHESIA AND INTENSIVE CARE, 2017;

FI: 1,695; Q3

Mondejar, E.F.

Considerations on the low adherence to clinical practice guidelines

INTENSIVE MEDICINE, 2017;

FI: 1,231; Q4

Slim, MCM; Garmendia, JLG; Cabanes, MPF; Fernandez-Mondejar, E.

Professional Competence and Teamwork in the Treatment of Patients With Acute and Critical Heart Disease

SPANISH JOURNAL OF CARDIOLOGY, 2016;

FI: 4,596; Q1

Rossaint, R; Bouillon, B; Cerny, V; Coats, TJ; Duringau, J; Fernandez-Mondejar, E; Filipescu, D; Hunt, BJ; Komadina, R; Nardi, G; Neugebauer, EAM; Ozier, Y; Riddez, L; Schultz, A; Vincent, JL; Spahn, DR

The European guideline on management of major bleeding and coagulopathy following trauma: fourth edition

CRITICAL CARE, 2016;

FI: 4,95; Q1

Perel, A; Saugel, B; Teboul, JL; Malbrain, MLNG; Belda, FJ; Fernandez-Mondejar, E; Kirov, M; Wendon, J; Lussman, R; Maggiorini, M.

The effects of advanced monitoring on hemodynamic management in critically ill patients: a pre and post questionnaire study

JOURNAL OF CLINICAL MONITORING AND COMPUTING, 2016;

FI: 1,819; Q3

Chico-Fernandez, M; Llompart-Pou, J.A.; Sanchez-Casado, M; Alberdi-Odriozola, F; Guerrero-Lopez, F; Mayor-Garcia, MD; Egea-Guerrero, JJ; Fernandez-Ortega, JF; Bueno-Gonzalez, A; Gonzalez-Robledo, J; Servia-Goixart, L; Roldan-Ramirez, J; Ballesteros-Sanz, MA; Tejerina-Alvarez, E; Pino-Sanchez, F.I.; Homar-Ramirez, J.

Mortality prediction using TRISS methodology in the Spanish ICU Trauma Registry (RETRAUCI)

INTENSIVE MEDICINE, 2016;

FI: 1,193; Q4

Round-Orts, M; Navarro-Guillamon, L; Garcia-Delgado, M; Serrano-Martinez, JL; Navarrete-Sanchez, I; Esteban-Molina, M.

Severe hypoxemia due to intracardiac shunting secondary to thrombosis of a tricuspid valve prosthesis

INTENSIVE MEDICINE, 2016;

FI: 1,193; Q4

Blanch, L; Villagra, A; Sales, B; Montanya, J; Lucangelo, U; Lujan, M; Garcia-Esquirol, O; Chacon, E; Struga, A; Oliva, JC; Hernandez-Abadia, A; Albaiceta, GM; Fernandez-Mondejar, E; Fernandez, R; Lopez-Aguilar, J; Villar, J; Murias, G; Kacmarek, RM

Asynchronies during mechanical ventilation are associated with mortality

INTENSIVE CARE MEDICINE, 2015;

FI: 7,214; D1

Curiel-Balsera, E; Munoz-Bono, J; Olea-Jimenez, V; Sanchez-Cantalejo, E; Sanchez-Rodriguez, AC; Garcia-Delgado, M; Arias-Verdu, MD; Rivera-Fernandez, R.

Preoperative use of statins does not improve outcomes and development of acute renal failure after cardiac surgery. A propensity score analysis of ARIAM-Andalucia database

ANESTHESIOLOGICAL MINERVA, 2015;

FI: 2,134; Q2

Diaz-Rubia, L; Ramos-Saez, S; Vazquez-Guillamet, R; Guerrero-Lopez, F; Pino-Sanchez, F; Garcia-Delgado, M; Gomez-Jimenez, FJ; Fernandez-Mondejar, E.

Efficacy of an extravascular lung water-driven negative fluid balance protocol.

INTENSIVE MEDICINE, 2015;

FI: 1,336; Q4

Garnacho-Montero, J; Fernandez-Mondejar, E; Ferrer-Roca, R; Herrera-Gutierrez, ME; Lorente, J.A.; Ruiz-Santana, S; Artigas, A.

Crystalloids and colloids in critical patient resuscitation

INTENSIVE MEDICINE, 2015;

FI: 1,336; Q4

Llau, JV; Acosta, FJ; School, G; Fernandez-Mondejar, E; Guasch, E; Marco, P; Paniagua, P; Paramo, JA; Quintana, M; Torrabadella, P

Multidisciplinary consensus document on the management of massive haemorrhage (HEMOMAS document)

INTENSIVE MEDICINE, 2015;

FI: 1,336; Q4

STUDY OF THE RESISTOME IN THE CRITICAL PATIENT. MODIFYING FACTORS OF THE INTESTINAL MICROBIOTA AND THEIR RELATIONSHIP WITH COLONIZATION AND INFECTION BY MULTIRESISTANT BACTERIA

Funder: UNIVERSITY OF GRANADA

File number: C-CTS-310-UGR23

Execution time: 01/01/2024 - 31/12/2026

IP: MANUEL COLMENERO RUIZ

Identification of the Differential Pattern of Circulating Microrn in the Child Patient With Bicuspid Aortic Valve and Study of Induced Cellular and Molecular Alterations in Endothelial Cells and Cardiomyocytes

Funder: COUNCIL OF HEALTH

File number: PC-0527-2017

Execution time: 01/01/2018 - 31/12/2020

PI: MANUEL JOSE GARCIA DELGADO

Exploratory study to evaluate the efficacy and safety of nutritional administration of 1,5 g of protein/kg/day versus 1,0 g of protein/kg/day in the catabolic phase of critically ill patients under mechanical ventilation

Funder: SPANISH SOCIETY OF INTENSIVE AND CRITICAL MEDICINE AND CORONARY UNITS

Type of test: INDEPENDENT CLINICAL TRIAL

Execution time: 05/11/2021 - 30/12/2022

IP: MANUEL COLMENERO RUIZ

Exploratory study to evaluate the efficacy and safety of nutritional administration of 1,5 g of protein/kg/day versus 1,0 g of protein/kg/day in the catabolic phase of critically ill patients under mechanical ventilation.

Funder: SPANISH SOCIETY OF INTENSIVE AND CRITICAL MEDICINE AND CORONARY UNITS

Type of test: INDEPENDENT CLINICAL TRIAL

Execution time: 05/11/2021 - 30/12/2022

IP: FRANCISCO LUIS MANZANO MANZANO

Double-blind randomized clinical trial comparing norepinephrine plus placebo versus norepinephrine plus terlipressin in septic shock

Funder: ANDALUSIAN PUBLIC FOUNDATION FOR HEALTH RESEARCH MANAGEMENT OF SEVILLE

Type of test: INDEPENDENT CLINICAL TRIAL

Execution time: 20/12/2021 - 30/06/2024

IP: MANUEL COLMENERO RUIZ

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Responsible researcher

MANUEL COLMENERO RUIZ

  • manuel.colmenero.sspa@juntadeandalucia.es
  • More Information
  • ORCID

Research

  • Collaboration network between groups of the ibs.GRANADA
  • Oncology Area
  • Epidemiology and Public Health Area
  • Precision Medicine Area
  • Advanced Therapies and Biomedical Technologies Area
  • Clinical research

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MP22-Biochemistry of Nutrition. Therapeutic Implications
MPE05-Translational Research in Cardiovascular Diseases

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