MP18-Uromet and Urooncology
Precision Medicine / IBS-MP18 / Consolidated
Group led by Dr. Miguel Arrabal Martín, attached to the Clinical Management Unit of the University Hospitals of Granada. The group is made up of 10 components, all with care activity except one methodological support technician in research. The staff includes specialists in urology, endocrinology and nutrition, and family and community medicine. Group formed mainly by specialists in Urology focused on studying the relationship between urological diseases such as kidney stones or erectile dysfunction and their relationship with endocrine-metabolic pathologies.
Research lines
- Biomarkers and diagnosis of uro-oncological diseases
- Lithogenesis and renal lithiasis treatment. Application of bone remodeling markers in patients with calcium kidney stones and loss of bone mass
- Metabolic syndrome, acute phase reactants and biomarkers in urological pathology
- New molecules in the treatment of urological cancer
- Genetics and Urology
Keywords
Calcium Renal Lithiasis. Lithogenic activity. Osteopenia Osteoporosis. Markers of bone remodeling. Metabolic syndrome. Inflammatory parameters.
Francisco Gutierrez Tejero
Maria Teresa Melgarejo Segura
ANTONIO JIMENEZ PACHECO
MIGUEL QUESADA CHARNECO
MIGUEL ARRABAL MARTIN
Mª CARMEN CANO GARCIA
ISABEL CASTILLO PEREZ
CARLOS FUNES PADILLA
JUAN GARRIDO GOMEZ
FERNANDO LOPEZ CARMONA PAINTED
FELIX ABAD MINOR
MIGUEL ANGEL ARRABAL POLO SHIRT
Efficacy of conduction hyperthermia in the treatment of non-muscle invasive bladder cancer: A systematic review
UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS, 2024;
FI: 2,4; Q2
Paravesical aggressive angiomyxoma, a rare cause of pelvic tumor in men
INTERNATIONAL UROLOGY AND NEPHROLOGY, 2024;
FI: 1,8; Q3
Preliminary results of the external urinary sphincter Uroflex® on the quality of life of patients with male urinary incontinence after prostate surgery: tolerance, severity of incontinence, and quality of life
INTERNATIONAL UROLOGY AND NEPHROLOGY, 2024;
FI: 1,8; Q3
Initial results of pulsed thulium fiber laser (Dornier ® ) for the treatment of renal and ureteral stones with ureteroscopy
SPANISH UROLOGICAL RECORDS, 2024;
FI: 1,2; Q3
Giant midline prostatic cyst: an unusual cause of acute urinary retention
Arch Esp Urol., 2024;
FI: 0,6; Q4
Prostate health index (PHI) as an accurate prostate cancer predictor
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, 2023;
FI: 3,6; Q2
Results of fusion prostate biopsy comparing with cognitive and systematic biopsy
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, 2023;
FI: 3,6; Q2
Use of polidocanol foam sclerotherapy for the treatment of lymphatic complications in primary female urethral carcinoma
INTERNATIONAL UROLOGY AND NEPHROLOGY, 2023;
FI: 2; Q3
Evaluation of tumor size and rete testis invasion in progression free survival of our patients with stage I testicular seminoma. A retrospective observational study of a reference hospital center and literature review
SPANISH UROLOGICAL RECORDS, 2023;
FI: 1,1; Q4
Electromotive Drug Administration Chemotherapy with Mitomycin C Versus Bacillus Calmette-Guerin for the Treatment of Non-Muscle Invasive Bladder Cancer
BLADDER CANCER, 2023;
FI: 1,1; Q4
Dietary Patterns and Prostate Cancer: CAPLIFE Study.
CANCER, 2022;
FI: 6,575; Q1
Obesity and biochemical recurrence in clinically localized prostate cancer: a systematic review and meta-analysis of 86,490 patients
PROSTATE CANCER AND PROSTATIC DISEASES, 2022;
FI: 5,455; Q1
References Values of Soluble alpha-Klotho Serum Levels Using an Enzyme-Linked Immunosorbent Assay in Healthy Adults Aged 18-85 Years
JOURNAL OF CLINICAL MEDICINE, 2022;
FI: 4,964; Q2
Allium stent placement after ureteral avulsion repair
INTERNATIONAL UROLOGY AND NEPHROLOGY, 2022;
FI: 2,266; Q3
Identification of hereditary breast and ovarian cancer germline variants in Granada (Spain): NGS perspective
MOLECULAR GENETICS AND GENOMICS, 2022;
FI: 2,98; Q3
Hypophosphatasia: A Unique Disorder of Bone Mineralization.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2021;
FI: 5,924; Q1
Safety and Efficacy Study of Collagenase Clostridium Histolyticum Applied With an Intensive Protocol in the Treatment of Peyronie's Disease
SEXUAL MEDICINE, 2021;
FI: 2,491; Q2
Pneumorachis and spondylodiscitis caused by emphysematous pyelonephritis
INTERNATIONAL UROLOGY AND NEPHROLOGY, 2021;
FI: 2,37; Q3
Adaptation of surgery practice during the Covid-19 pandemic. Ureteroscopy in outpatient surgery
SPANISH ARCHIVES OF UROLOGIA, 2021;
FI: 0,436; Q4
Assessment of radiopaque kidney stone treatment: Combination of extracorporeal shock wave lithotripsy and Fagolitos Plus (R). Preliminary case control description
SPANISH ARCHIVES OF UROLOGIA, 2021;
FI: 0,436; Q4
Melatonin / Nrf2 / NLRP3 Connection in Mouse Heart Mitochondria during Aging
ANTIOXIDANTS, 2020;
FI: 5,014; D1
Dietary Diversity and Prostate Cancer in a Spanish Adult Population: CAPLIFE Study
NUTRIENTS, 2020;
FI: 4,546; Q1
HPLC-MS / MS method for the determination of perfluoroalkyl substances in breast milk by combining salt-assisted and dispersive liquid-liquid microextraction
ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2020;
FI: 3,637; Q1
Factors Predicting the Response to a Vitamin D-Fortified Milk in Healthy Postmenopausal Women
NUTRIENTS, 2019;
FI: 4,171; Q1
Linking of psoriasis with osteopenia and osteoporosis: A cross-sectional study
INDIAN JOURNAL OF DERMATOLOGY VENEREOLOGY & LEPROLOGY, 2019;
FI: 3,03; Q2
A preliminary survey of practice patterns across several European kidney stone centers and a call for action in developing shared practice
UROLITHIASIS, 2019;
FI: 1,671; Q3
Ureteral stent disintegrated
SPANISH ARCHIVES OF UROLOGIA, 2019;
FI: 0,335; Q4
Treatment of ureterorenal stones with shock wave lithotripsy. Results and complications with the dornier gemini emse 220f-XXP
SPANISH ARCHIVES OF UROLOGIA, 2019;
FI: 0,335; Q4
Effects of Daily Intake of Calcium and Vitamin D-Enriched Milk in Healthy Postmenopausal Women: A Randomized, Controlled, Double-Blind Nutritional Study.
JOURNAL OF WOMEN'S HEALTH, 2018;
FI: 2,097; D1
Chronic periodontitis is associated with erectile dysfunction. A case-control study in European population
JOURNAL OF CLINICAL PERIODONTOLOGY, 2018;
FI: 4,046; D1
Risk of renal stone formation in patients treated with luteinising hormone-releasing hormone analogues for prostate cancer: importance of bone metabolism and urine calcium.
INTERNATIONAL UROLOGY AND NEPHROLOGY, 2018;
FI: 1,692; Q3
Altered urinary calcium excretion in prostate cancer patients subjected to androgen deprivation. Preliminary pilot study results
SPANISH ARCHIVES OF UROLOGIA, 2018;
FI: 0,465; Q4
Assessing robot-assisted laparoscopic prostatectomy
LANCET, 2017;
FI: 47,831; D1
Hematospermia as a Rare Form of Presentation of Zinner Syndrome
UROLOGY, 2017;
FI: 2,309; Q2
Androgen deprivation therapy in prostate cancer and risk of developing renal calculus: Results of a case-control study
CLINICAL MEDICINE, 2017;
FI: 1,125; Q3
The value of hypercalciuria in patients with osteopenia versus osteoporosis
UROLITHIASIS, 2017;
FI: 1,816; Q3
Lixisenatide in patients with type 2 diabetes and obesity: Beyond glycemic control
PRIMARY CARE, 2017;
FI: 1,042; Q3
Ex vivo construction of a novel model of bioengineered bladder mucosa: A preliminary study
INTERNATIONAL JOURNAL OF UROLOGY, 2016;
FI: 1,878; Q2
Analysis of vitamin D deficiency in calcium stone-forming patients
INTERNATIONAL UROLOGY AND NEPHROLOGY, 2016;
FI: 1,292; Q3
Bone remodeling markers as lithogenic risk factors in patients with osteopenia-osteoporosis.
INTERNATIONAL UROLOGY AND NEPHROLOGY, 2016;
FI: 1,292; Q3
Hyperparathyroidism in patients with stones. Influence of 25-OH vitamin D deficiency
PRIMARY CARE, 2016;
FI: 1,098; Q3
Urine Calcium and Bone Mineral Density in Calcium Stone-Forming Patients Treated with Alendronate and Hydrochlorothiazide
UROLOGY INTERNATIONALIS, 2016;
FI: 1,313; Q3
Re: Jodi A. Antonelli, Naim M. Maalouf, Margaret S. Pearle, Yair Lotan. Use of the National Health and Nutrition Examination Survey to Calculate the Impact of Obesity and Diabetes on Cost and Prevalence of Urolithiasis in 2030. Eur Urol 2014; 66: 724-9
EUROPEAN UROLOGY, 2015;
FI: 13,938; D1
STONES Bone health in patients with kidney stones
NATURE REVIEWS UROLOGY, 2015;
FI: 4,84; D1
Expulsive medical treatment of ureteral stone with adrenergic alpha-blockers
CLINICAL MEDICINE, 2015;
FI: 1,417; Q2
Retrospective Review of Serum and Urinary Lithogenic Risk Factors in Patients With Osteoporosis and Osteopenia
UROLOGY, 2015;
FI: 2,188; Q2
The importance of calciuria as lithogenic factors in patients with osteopenia / osteoporosis
INTERNATIONAL UROLOGY AND NEPHROLOGY, 2015;
FI: 1,519; Q3
Single-center post-authorization clinical study to evaluate the efficacy and safety of microcurrent neuromodulation (NESA9) versus posterior tibial nerve electrostimulation (PTENS) in the treatment of overactive bladder.
Funder: Alejandro Otero Foundation for Biosanitary Research of Eastern Andalusia (FIBAO)
Test type: OBSERVATIONAL STUDY WITH MEDICINES
Execution time: 08/07/24 - 30/03/25
PI: MIGUEL ARRABAL MARTIN
Efficacy and safety of co-administration of cagrilintide/semaglutide (CagriSema) 1,0 mg/1,0 mg sc once weekly versus tirzepatide 5 mg sc once weekly in participants with inadequately controlled type 2 diabetes receiving metformin, an SGLT2 inhibitor, or both. REIMAGINE 5
Financier: NOVO NORDISK A/S
Type of test: CLINICAL TRIAL WITH DRUGS
Execution time: 19/06/2024 - 30/09/2026
IP: MIGUEL QUESADA CHARNECO
RANDOMIZED, OPEN CLINICAL TRIAL TO EVALUATE BLADDER INSTILATION OF NEOADJUVANT CHEMOTHERAPY TO TRANSURETHRAL BLADDER RESECTION FOR THE PREVENTION OF RECURRENCE OF NON-MUSCLE INVASIVE UROTHELIAL CARCINOMA.
Financier: MARTÍNEZ-PIÑEIRO
Type of test: INDEPENDENT CLINICAL TRIAL
Execution time: 29/03/2022 - 31/12/2029
PI: MIGUEL ARRABAL MARTIN
Phase 3, Randomized, Comparative, Open-label, Parallel Group Study to Compare the Efficacy and Safety of LY3209590 as Weekly Basal Insulin with That of Insulin Glargine in Adults with Type 2 Diabetes Receiving Multiple Daily Injections
Funder: ELI LILLY AND COMPANY
Type of test: CLINICAL TRIAL WITH DRUGS
Execution time: 06/10/2022 - 30/11/2023
IP: MIGUEL QUESADA CHARNECO
Neoadjuvant versus adjuvant chemotherapy in urothelial carcinoma of the upper urinary tract. Phase II Randomized Clinical Trial of Feasibility (URANUS)
Funder: EUROPEAN URO-ONCOLOGY GROUP (EUOG)
Type of test: INDEPENDENT CLINICAL TRIAL
Execution time: 07/04/2022 - 30/12/2025
PI: MIGUEL ARRABAL MARTIN
a phase III, randomized, open-label trial evaluating the efficacy of atezolizumab administered concomitantly with bladder instillations of BCG (Bacille Calmette-Guérin) for one year in patients with non-muscle-invasive bladder cancer at high risk of recurrence and who have not been previously treated with BCG. ALBAN
Funder: GCS UNICANCER
Type of test: COMMERCIAL CLINICAL TRIAL
Execution time: 22/04/2022 - 30/01/2028
PI: MIGUEL ARRABAL MARTIN
Phase 3, randomized, double-blind, placebo-controlled study to investigate the effect of tirzepatide on reducing morbidity and mortality in adults with obesity
Financier: LILLY, SA
Type of test: CLINICAL TRIAL WITH DRUGS
Execution time: 14/11/2022 - 30/09/2027
IP: MIGUEL QUESADA CHARNECO
Phase 2, multicenter, randomized, open-label study of TAR-200 in combination with cetrelimab and cetrelimab monotherapy in participants with muscle-invasive urothelial carcinoma of the bladder who are to be treated with radical cystectomy and are ineligible or refuse treatment with platinum-based neoadjuvant chemotherapy (SUNRISE)
Funder: JANSSEN-CILAG, SA
Type of test: COMMERCIAL CLINICAL TRIAL
Execution time: 05/05/2022 - 28/07/2025
PI: MIGUEL ARRABAL MARTIN
Prospective randomized comparative study to assess the usefulness of the use of prophylactic mesh to prevent parastomal hernia after cystectomy and ileal conduit. Uromesh-CUETO 1803 study.
Funder: FOUNDATION FOR RESEARCH IN UROLOGY
Type of test: INV. INDEP SANITARY PRODUCT CLINIC.
Execution time: 30/06/2022 - 30/12/2022
PI: MIGUEL ARRABAL MARTIN
Multicenter Clinical Trial with a health product associated with a drug in therapeutic use authorized for the treatment of CVNMI, evaluating the efficacy and tolerability of adjuvant treatment with EMDA-MMC versus standard BCG and the efficacy of the biomarker
Financer: PRESURGY, SL
Type of test: INV. CLINICA PRODUCT SANITARIO COM.
Execution time: 01/07/2021 - 30/12/2026
PI: MIGUEL ARRABAL MARTIN
Prospective observational study on the use of transmucosal fentanyl citrate in routine clinical practice for the control of breakthrough pain crises in cancer patients
Financier: FERRER INTERNATIONAL SA
Type of test: COMMERCIAL POST AUTHORIZATION STUDY
Execution time: 24/07/2020 - 30/09/2020
IP: ISABEL CASTILLO PEREZ
Experimental study of the administration of a food supplement containing hydroxycitric acid versus placebo in patients with oxalate and calcium phosphate lithiasis in whom extracorporeal shock wave lithotripsy is indicated
Financier: ARAFARMA GROUP SA
Test Type: CLINICAL FOOD STUDIES
Execution time: 30/01/2020 - 30/08/2020
PI: MIGUEL ARRABAL MARTIN
Observational study on the management of castration-resistant prostate cancer with unknown metastatic status in clinical practice. APHRODITE
Funder: JANSSEN-CILAG, SA
Type of test: COMMERCIAL POST AUTHORIZATION STUDY
Execution time: 23/12/2019 - 30/04/2021
PI: MIGUEL ARRABAL MARTIN
