MP15-Liver Diseases and Colorectal Cancer

Information
Members
Patents
Publications
Projects
Clinical trials

Multidisciplinary group made up of clinical researchers (specialists in Digestive, Radiation Oncology and General Surgery and of the Digestive System) and basic researchers oriented towards the study of liver diseases associated with obesity and liver and colorectal cancer.

Research lines

Application of nanotechnology to the manufacture of massive sequencing libraries with reduced cost and biases, analysis of circulating miRNAs with reduced cost and increased efficiency and improved flow cytometry applied to tissue
Cancer stem cells in relation to the tumor niche in colorectal and liver cancer
Development of new treatments for cancer
Cancer immune avoidance
Pathophysiology of oxidative stress
Obesity: Analysis of adipose tissue cell populations in relation to fatty liver disease in morbid obesity
Immune function of adipose tissue and its implication in the development of type 2 diabetes mellitus and other pathologies associated with obesity
Immune memory in viral infections: hepatitis C and B, cytomegalovirus and SARS-CoV-2

Keywords

Obesity, diabetes, NAFLD, cancer stem cells, tumor niche, ROS / RNS, nanotechnology

NICOLE HERNANDEZ QUEZADA

ORCID

MARIA JOSE MUÑOZ DOMENE

Paula Sanchez Uceta

Carlos Arana Molina

Charity Diaz Navarro

ORCID

ADELINA GARCIA ROBLES

DAVID LOPEZ PEREZ

ORCID

ALICIA MARTIN-LAGOS MALDONADO

MARIA SOL ZURITA SAAVEDRA

ORCID

JESUS GARCIA RUBIO

ORCID

ANA GILA MEDINA

CRISTINA GONZALEZ PUGA

JOSEPH LEON LOPEZ

MARIA DEL PILAR MARTINEZ TIRADO

ANAIS REDRUELLO ROMERO

ORCID

JULIA ESCUDERO FELIU

ORCID

Inventors: Javier Salmerón; Angeles Ruiz Extremera; Esther Pavón; Paloma Muñoz de Rueda; Jose Antonio Muñoz Gámez; Rosa Quiles Pérez; Angel Carazo Gallego; Ana Gila Medina; Ana Belén Marín Álvarez; Sergio Manuel Jiménez Ruiz; Josefa León López; Jorge Casado Ruiz
Title: Method of obtaining useful data to predict or predict vertical transmission, chronification and / or clearance of the hepatitis C virus.
Code: PCT / ES2016 / 07115

Inventors: Ángeles Ruiz Extremera; Esther J. Pavón Castillero; Javier Salmerón Escobar; Paloma Muñoz de Rueda; José Antonio Muñoz Gámez; Jorge Casado Ruiz; Ángel Carazo Gallego; Rosa Quiles Pérez; Ana Gila Medina; Josefa León López; Ana B Martín Álvarez; Sergio Manuel Jim
Title: Method of obtaining useful data to predict or predict vertical transmission of the hepatitis C virus
Code: P201530221

Inventors: Ángeles Ruiz Extremera; Esther J. Pavón Castillero; Javier Salmerón Escobar; Paloma Muñoz de Rueda; José Antonio Muñoz Gámez; Jorge Casado Ruiz; Ángel Carazo Gallego; Rosa Quiles Pérez; Ana Gila Medina; Josefa León López; Ana B Martín Álvarez; Sergio Manuel Jim
Title: Method of obtaining useful data to predict or predict hepatitis C chronification and HCV clearance
Code: P201530222

Inventors: MIGUEL ANGEL LOPEZ NEVOT, JOSEFA LEON LOPEZ, ANA GILA MEDINA, JOSÉ ANTONIO MUÑOZ GÁMEZ, ROSA QUILES PÉREZ, PALOMA MUÑOZ DE RUEDA, ÁNGEL CARAZO GALLEGO, ESTHER JOSÉ PAVÓN CASTILLERO, ANA BELÉNIO MUÑOZ SALMON ESCO
Title: POLYMORPHISMS TO PREDICT OR FORECAST THE RESPONSE TO ANTIVIRAL TREATMENT
Code: P201430205

Inventors: JAVIER SALMERÓN ESCOBAR; PALOMA MUÑOZ DE RUEDA; ROSA QUILES PÉREZ; JOSE ANTONIO MUÑOZ GAMEZ; ESTHER JOSÉ PAVÓN CASTILLERO; ANA GILA MEDINA; MIGUEL ANGEL LOPEZ NEVOT; JORGE CASADO RUIZ; ANGELES RUIZ LEIZÓN EXTREMERA; ANA GILA CARRENO ANGELES;
Title: Specific mutations (L5P; L7P; L15S) in the immunodominant epitope HCV-NS3 (aa 1253-1272) against HLA-DQB1 * 0301 cause a non-response to antiviral treatment with pegIFN / RBV in patients with Chronic Hepatitis C genotype
Code: P-06781

González-Olmedo, C; García-Verdejo, FJ; Reguera-Teba, A; Rosa-Garrido, C; López-López, J.A.; Díaz-Beltrán, L.; García, PM; Luque-Caro, N; Gálvez-Montosa, F; Ortega-Granados, A.L.; Ruiz-Sanjuan, M; Cózar-Ibáñez, A; Sainz, J; Marchal, J.A.; Camacho, J; del Palacio, J.P.; Fernández-Godino, R; Díaz, C; Sánchez-Rovira, P

Metabolomics signature as a survival predictor in patients with resectable colorectal liver metastasis

CLINICAL AND TRANSLATIONAL MEDICINE, 2024;

FI: 7,9; D1

Pérez-Díaz, C; Pérez-Carrascosa, FM; Riquelme-Gallego, B; Villegas-Arana, E; Armendariz, AJ; Galindo-Angel, J; Frederiksen, H; León, J; Requena, P; Arrebola, J.P.

Serum Phthalate Concentrations and Biomarkers of Oxidative Stress in Adipose Tissue in a Spanish Adult Cohort

ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2024;

FI: 10,9; D1

Markovinovic, A; Martin-Guerrero, SM; Morotz, GM; Salam, S; Gomez-Suaga, P; Paillusson, S; Greig, J; Lee, Y; Mitchell, J.C.; Noble, W; Miller, C.J.

Stimulating VAPB-PTPIP51 ER-mitochondria tethering corrects FTD/ALS mutant TDP43 linked Ca2+ and synaptic defects

ACTA NEUROPATHOLOGICA COMMUNICATIONS, 2024;

FI: 6,2; D1

Cadenas-Garrido, P; Schonvandt-Alarcos, A; Herrera-Quintana, L; Vázquez-Lorente, H; Santamaría-Quiles, A; de Francisco, J.R.; Moya-Escudero, M; Martín-Oliva, D; Martín-Guerrero, S.M.; Rodríguez-Santana, C; Aragón-Vela, J; Plaza-Diaz, J.

Using Redox Proteomics to Gain New Insights into Neurodegenerative Disease and Protein Modification

ANTIOXIDANTS, 2024;

FI: 6; Q1

Martín-Leyva, A.; Peinado, F. M.; Ocón-Hernández, O.; Olivas-Martínez, A.; Luque, A.; León, J.; Lendínez, I.; Cardona, J.; Lara-Ramos, A.; Olea, N.; Fernández, M. F.; Artacho-Cordón, F.

Environmental Exposure to Persistent Organic Pollutants and Its Association with Endometriosis Risk: Implications in the Epithelial-Mesenchymal Transition Process

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2024;

FI: 4,9; Q1

Garzon-Furne, AI; Ferreiro-Marzala, A; Rodriguez-Serrano, F; Esteban-Molina, M; Garcia-Orta, R; Moreno-Escobar, E; Garcia-Delgado, M; Sevilla-Martinez, M; Gomez-Luque, JM; Ocete-Hita, E; Rodríguez-Vázquez del Rey, MD; Nuila-Durán, LM; Garrido, J.M.

Valve repair in mitral endocarditis

CARDIOVASCULAR SURGERY, 2023;

Peinado, FM; Olivas-Martinez, A; Iribarne-Duran, LM; Ubiña, A; Leon, J; Vela-Soria, F; Fernandez-Parra, J; Fernandez, MF; Olea, N; Freire, C; Ocon-Hernandez, O; Artacho-Cordon, F

Cell cycle, apoptosis, cell differentiation, and lipid metabolism gene expression in endometriotic tissue and exposure to parabens and benzophenones

SCIENCE OF THE TOTAL ENVIRONMENT, 2023;

FI: 9,8; D1

Redruello-Romero, A; Benitez-Cantos, MS; Lopez-Perez, D; Garcia-Rubio, J; Tamayo, F; Perez-Bartivas, D; Moreno-SanJuan, S; Ruiz-Palmero, I; Puentes-Pardo, JD; Vilchez, JR; Lopez-Nevot, MA; Garcia, F; Cano, C; Leon, J; Carazo, A

Human adipose tissue as a major reservoir of cytomegalovirus-reactive T cells

FRONTIERS IN IMMUNOLOGY, 2023;

FI: 7,3; Q1

Peinado, FM; Olivas-Martinez, A; Lendinez, I; Iribarne-Duran, LM; Leon, J; Fernandez, MF; Sotelo, R; Vela-Soria, F; Olea, N; Freire, C; Ocon-Hernandez, O; Artacho-Cordon, F

Expression Profiles of Genes Related to Development and Progression of Endometriosis and Their Association with Paraben and Benzophenone Exposure

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023;

FI: 5,6; Q1

Urrutia-Maldonado, E; Alés-Palmer, M; De Rueda, PM; Peláez-Pleguezuelos, I; Ocete-Hita, E

The relationship between activator and inhibitor killer-cell immunoglobulin-like receptors and hepatotoxicity in oncological treatment

MINERVA PEDIATRICS, 2023;

FI: 2,6; Q2

Lopez-Perez, D; Redruello-Romero, A; Garcia-Rubio, J; Arana, C; Garcia-Escudero, LA; Tamayo, F; Salmeron, J; Galvez, J; Leon, J; Carazo, A

In Obese Patients With Type 2 Diabetes, Mast Cells in Omental Adipose Tissue Decrease the Surface Expression of CD45, CD117, CD203c, and Fc epsilon RI

FRONTIERS IN ENDOCRINOLOGY, 2022;

FI: 6,055; Q1

Cuadros, MA; Sepulveda, MR; Martin-Oliva, D; Marin-Teva, J.L.; Neubrand, V.E.

Microglia and Microglia-Like Cells: Similar but Different

FRONTIERS IN CELLULAR NEUROSCIENCE, 2022;

FI: 6,147; Q1

Sanchez-Castillo, AI; Sepulveda, MR; Marin-Teva, J.L.; Cuadros, MA; Martin-Oliva, D; Gonzalez-Rey, E; Delgado, M; Neubrand, V.E.

Switching Roles: Beneficial Effects of Adipose Tissue-Derived Mesenchymal Stem Cells on Microglia and Their Implication in Neurodegenerative Diseases

BIOMOLECULES, 2022;

FI: 6,064; Q2

Regalado, SP; Leon, J; Feriche, B

Therapeutic approaches for digestive system cancers and potential implications of exercise under hypoxia condition: what little is known? a narrative review

JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, 2022;

FI: 4,322; Q2

Perez, RF; Sanfiel, JR; Lopez, PD; Rubio, J.G.

Wandering liver as a cause of intestinal obstruction

GASTROENTEROLOGY AND HEPATOLOGY, 2022;

FI: 5,867; Q2

Mustieles, V; Perez-Carrascosa, FM; Leon, J.; Lange, T.; Bonde, JP; Gomez-Pena, C; Artacho-Cordon, F; Barrios-Rodriguez, R; Olmedo-Requena, R; Exposito, J.; Jimenez-Moleon, JJ; Arrebola, J.P.

Adipose Tissue Redox Microenvironment as a Potential Link between Persistent Organic Pollutants and the 16-Year Incidence of Non-hormone-Dependent Cancer

ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2021;

FI: 9,028; D1

Galban-Velazquez, S; Stephen, J.; Cakmak, G; Artacho-Cordon, F; Leon, J.; Barrel, J; Vela-Soria, F; Martin-Olmedo, P; Fernandez, M.F.; Pellin, MC; Arrebola, J.P.

Associations of persistent organic pollutants in human adipose tissue with retinoid levels and their relevance to the redox microenvironment..

ENVIRONMENTAL RESEARCH, 2021;

FI: 6,498; D1

Hairstyle, FM; Ocon-Hernandez, O; Iribarne-Duran, LM; Vela-Soria, F; Ubina, A; Padilla, C; Mora, JC; Cardona, J.; Leon, J.; Fernandez, M.F.; Olea, N.; Artacho-Cordon, F.

Cosmetic and personal care product use, urinary levels of parabens and benzophenones, and risk of endometriosis: results from the EndEA study.

ENVIRONMENTAL RESEARCH, 2021;

FI: 6,498; D1

Aroca-Siendones, MI; Moreno-San Juan, S; Puentes-Pardo, JD; Verbeni, M; Arnedo, J.; Escudero-Feliu, J; Garcia-Costela, M; Garcia-Robles, A; Carazo, A; Leon, J.

Core Circadian Clock Proteins as Biomarkers of Progression in Colorectal Cancer

BIOMEDICINE, 2021;

FI: 6,081; Q1

Rios-Arrabal, S; Puentes-Pardo, JD; Moreno-San Juan, S; Szuba, A; Married, J.; Garcia-Costela, M; Escudero-Feliu, J; Verbeni, M; Cano, C; Gonzalez-Puga, C; Maldonado, AML; Carazo, A; Leon, J.

Endothelin-1 as a Mediator of Heme Oxygenase-1-Induced Stemness in Colorectal Cancer: Influence of p53

JOURNAL OF PERSONALIZED MEDICINE, 2021;

FI: 4,945; Q1

Martin-Guerrero, SM; Married, P; Hijazi, M; Rajeeve, V; Plaza-Diaz, J; Abadia-Molina, F; Navascues, J; Cuadros, MA; Cutillas, PR; Martin-Oliva, D

PARP-1 activation after oxidative insult promotes energy stress-dependent phosphorylation of YAP1 and reduces cell viability

BIOCHEMICAL JOURNAL, 2020;

FI: 4,097; Q2

Artacho-Cordon, F; Rios-Arrabal, S; Leon, J; Frederiksen, H; Saenz, JM; Martin-Olmedo, P; Fernandez, M.F.; Olea, N; Arrebola, JP

Adipose tissue concentrations of non-persistent environmental phenols and local redox balance in adults from Southern Spain

ENVIRONMENT INTERNATIONAL, 2019;

FI: 7,943; D1

Leon, J; Saenz, JM; Artacho-Cordon, F; Fernandez, M.F.; Martin-Olmedo, P; Salamanca-Fernandez, E; Gomez-Pena, C; Olea, N; Arrebola, JP

Contribution of sociodemographic, occupational, lifestyle and dietary characteristics to the oxidative stress microenvironment in adipose tissue.

ENVIRONMENTAL RESEARCH, 2019;

FI: 5,026; D1

Salinas-Asensio, M.M.; Rios-Arrabal, S; Artacho-Cordon, F; Olivares-Urbano, MA; Calvente, I; Leon, J; Nunez, MI

Exploring the radiosensitizing potential of magnetotherapy: a pilot study in breast cancer cells

INTERNATIONAL JOURNAL OF RADIATION BIOLOGY, 2019;

FI: 2,266; D1

Martin-Guerrero, SM; Married, P; Munoz-Gamez, JA; Carrasco, MC; Navascues, J; Cuadros, MA; Lopez-Gimenez, JF; Cutillas, PR; Martin-Oliva, D

Poly (ADP-Ribose) Polymerase-1 inhibition potentiates cell death and phosphorylation of DNA damage response proteins in oxidative stressed retinal cells

EXPERIMENTAL EYE RESEARCH, 2019;

FI: 2,998; Q1

Morales-Santana, S; Morell, S; Leon, J; Carazo-Gallego, A; Jimenez-Lopez, JC; Morell, M.

An Overview of the Polymorphisms of Circadian Genes Associated With Endocrine Cancer

FRONTIERS IN ENDOCRINOLOGY, 2019;

FI: 3,634; Q2

Ampuero, J; Jimeno, C; Quiles, R; Rosales, JM; Llerena, S; Palomo, N; Lamb, P; Serrano, FJ; Urquijo, JJ; Moreno-Planas, JM; Ontanilla, G; Hernandez, M; Ortega-Alonso, A; Maraver, M; Bonacci, M; Rojas, A; Figueruela, B; Forns, X; Andrade, RJ; Calleja, JL; Diago, M; Carmona, I; de la Mata, M; Buti, M; Crespo, J; Pascasio, JM; Navarro, JM; Salmeron, J; Romero-Gomez, M

Impact of comorbidities on patient outcomes after interferon-free therapy-induced viral eradication in hepatitis C.

Journal of Hepatology, 2018;

FI: 15,04; D1

Garcia-Rubio, J; Leon, J; Redruello-Romero, A; Pavón, E; Cook, A; Tamayo, F; Caba-Molina, M; Salmeron, J; Carazo, A.

Cytometric analysis of adipose tissue reveals increases of adipocyte progenitor cells after weight loss induced by bariatric surgery

SCIENTIFIC REPORTS, 2018;

FI: 4,122; Q1

Lima-Hair, E; Morales-Santana, S; Leon, J; Alche, V; Clemente, A; Alche, JD; Jimenez-Lopez, JC

Narrow-leafed lupine (Lupinus angustifolius L.) seed -conglutins reverse the induced insulin resistance in pancreatic cells

FOOD & FUNCTION, 2018;

FI: 3,289; Q1

Guidi, G; Married, J; Ascasibar, Y; Garcia-Benito, R; Galbany, L; Sanchez-Blazquez, P; Sanchez, SF; Rosales-Ortega, FF; Scannapieco, C

The SELGIFS data challenge: generating synthetic observations of CALIFA galaxies from hydrodynamic simulations

MONTHLY NOTICES OF THE ROYAL ASTRONOMICAL SOCIETY, 2018;

FI: 5,194; Q1

de la Oliva, P; Cambra-Lasaosa, FJ; Quintana-Diaz, M; Rey-Galan, C; Sanchez-Diaz, JI; Martin-Delgado, MC; from Carlos-Vicente, JC; Hernandez-Rastrollo, R; Holland-Pena, MS; Pilar-Orive, FJ; Ocete-Hita, E; Rodriguez-Nunez, A; Serrano-Gonzalez, A; Blanch, L

Admission, discharge and triage guidelines for pediatric intensive care units in Spain

ANNALS OF PEDIATRICS, 2018;

FI: 1,318; Q3

Carrillo, CF; Lens, S; Llop, E; Pascasio, JM; Crespo, J; Arenas, J; Fernandez, R; Baliellas, C; Carrion, JA; de la Mata, M; Buti, M; Castells, L; Albillos, A; Romero, M; Turnes, J; Pons, C; Moreno-Planas, JM; Moreno-Palomares, JJ; Fernandez-Rodriguez, C; Garcia-Samaniego, J; Prieto, M; Bermejo, MF; Salmeron, J; Badia, E; Salcedo, M; Herrero, JI; Granados, R; Ble, M; Marino, Z; Calleja, JL

Treatment of Hepatitis C Virus Infection in Patients With Cirrhosis and Predictive Value of Model for End-Stage Liver Disease: Analysis of Data From the Hepa-C Registry

HEPATOLOGY, 2017;

FI: 13,246; D1

Martin-Guerrero, SM; Munoz-Gamez, J.A.; Carrasco, M.C.; Salmeron, J; Martin-Estebane, M; Pictures, M.A.; Navascues, J; Martin-Oliva, D.

Poly (ADP-ribose) polymerases inhibitors prevent early mitochondrial fragmentation and hepatocyte cell death induced by H2O2

PLOSONE, 2017;

FI: 2,806; Q1

de Rueda, PM; Jimenez-Ruiz, SM; Quiles, R; Pavon-Castillero, EJ; Munoz-Gamez, JA; Married, J; Gila, A; Ruiz-Extremera, A; Salmeron, J

The antigenic variability of HCV in viral HLA-Ag binding is related to the activation of the host immune response

SCIENTIFIC REPORTS, 2017;

FI: 4,259; Q1

Ocete-Hita, E; Salmeron-Fernandez, MJ; Urrutia-Maldonado, E; Munoz-de-Rueda, P; Salmeron-Ruiz, M; Martinez-Padilla, MC; Ruiz-Extremera, A.

Analysis of Immunogenetic Factors in Idiosyncratic Drug-induced Liver Injury in the Pediatric Population.

JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION, 2017;

FI: 2,799; Q1

Ruiz-Extremera, A; Pavon-Castillero, EJ; Florido, M; de Rueda, PM; Munoz-Gamez, JA; Married, J; Carazo, A; Quiles, R; Jimenez-Ruiz, SM; Gila, A; Luna, JD; Leon, J; Salmeron, J

Influence of HLA class I, HLA class II and KIRs on vertical transmission and chronicity of hepatitis C virus in children.

PLOSONE, 2017;

FI: 2,806; Q1

Artacho-Cordon, F; Leon, J; Saenz, JM; Fernandez, M.F.; Martin-Olmedo, P; Olea, N; Arrebola, JP

Contribution of Persistent Organic Pollutant Exposure to the Adipose Tissue Oxidative Microenvironment in an Adult Cohort: A Multipollutant Approach

ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2016;

FI: 5,393; D1

Munoz-Gamez, J.A.; Salmeron, J; Ruiz-Extremera, A.

Hepatitis C during pregnancy, vertical transmission and new treatment possibilities

CLINICAL MEDICINE, 2016;

FI: 1,267; Q2

Quer, J; Gregori, J; Rodriguez-Frias, F; Buti, M; Madejon, A; Perez-del-Pulgar, S; Garcia-Cehic, D; Casillas, R; Blasi, M; Homs, M; Tabernero, D; Alvarez-Tejado, M; Munoz, JM; Cubero, M; Knight, A; delCampo, JA; Sunday, E; Belmonte, I; Nieto, L; Lens, S; Munoz-de-Rueda, P; Sanz-Cameno, P; Sauleda, S; Bes, M; Gomez, J; Briones, C; Perales, C; Sheldon, J; Castells, L; Viladomiu, L; Salmeron, J; Ruiz-Extremera, A; Quiles-Perez, R; Moreno-Otero, R; Lopez-Rodriguez, R; Allende, H; Romero-Gomez, M; Guard, J; Esteban, R; Garcia-Samaniego, J; Forns, X; Esteban, JI

High-Resolution Hepatitis C Virus Subtyping Using NS5B Deep Sequencing and Phylogeny, an Alternative to Current Methods (vol 53, pg 219, 2015)

JOURNAL OF CLINICAL MICROBIOLOGY, 2016;

FI: 3,631; Q2

Cabrera-Martos, I; Valenza, M.C.; Valenza-Demet, G; Benitez-Feliponi, A; Robles-Vizcaino, C; Ruiz-Extremera, A.

Effects of manual therapy on treatment duration and motor development in infants with severe nonsynostotic plagiocephaly: a randomized controlled pilot study

CHILD'S NERVOUS SYSTEM, 2016;

FI: 1,08; Q3

Cabrera-Martos, I; Valenza, M.C.; Valenza-Demet, G; Benitez-Feliponi, A; Robles-Vizcaino, C; Ruiz-Extremera, A.

Repercussions of plagiocephaly on posture, muscle flexibility and balance in children aged 3-5 years old

JOURNAL OF PEDIATRICS AND CHILD HEALTH, 2016;

FI: 1,477; Q3

Munoz-Gamez, J.A.; Viota, JL; Barrientos, A; Carazo, A; Sanjuan-Nunez, L; Quiles-Perez, R; Munoz-de-Rueda, P; Slim, A; Ruiz-Extremera, A; Salmeron, J.

Synergistic cytotoxicity of the poly (ADP-ribose) polymerase inhibitor ABT-888 and temozolomide in dual-drug targeted magnetic nanoparticles

LIVER INTERNATIONAL, 2015;

FI: 4,85; Q1

Quer, J; Gregori, C; Rodriguez-Frias, F; Buti, M; Madejon, A; Perez-del-Pulgar, S; Garcia-Cehic, D; Casillas, R; Blasi, M; Homs, M; Tabernero, D; Alvarez-Tejado, M; Munoz, JM; Cubero, M; Knight, A; delcampo, JA; Sunday, E; Belmonte, I; Nieto, L; Lens, S; Munoz-de-Rueda, P; Sanz-Cameno, P; Sauleda, S; Bes, M; Gomez, J; Briones, C; Perales, C; Sheldon, J; Castells, L; Viladomiu, L; Salmeron, J; Ruiz-Extremera, A; Quiles-Perez, R; Moreno-Otero, R; Lopez-Rodriguez, R; Allende, H; Romero-Gomez, M; Guard, J; Esteban, R; Garcia-Samaniego, J; Forns, X; Esteban, JI

High-Resolution Hepatitis C Virus Subtyping Using NS5B Deep Sequencing and Phylogeny, an Alternative to Current Methods

JOURNAL OF CLINICAL MICROBIOLOGY, 2015;

FI: 3,993; Q1

Artacho-Cordon, F; Rios-Arrabal, S; Olivares-Urbano, MA; Storch, K; Dickreuter, E; Munoz-Gamez, J.A.; Leon, J; Calvente, I; Torne, P; Salinas, M.D.; Cordes, N; Nunez, MI

Valproic acid modulates radiation-enhanced matrix metalloproteinase activity and invasion of breast cancer cells.

INTERNATIONAL JOURNAL OF RADIATION BIOLOGY, 2015;

FI: 1,687; Q1

Ampuero, J; del Campo, J.A.; Rojas, L; Garcia-Lozano, R.J.; Buti, M; Alone, R; Forns, X; Moreno-Otero, R; Andrade, R; Diago, M; Salmeron, J; Rodrigo, L; Pons, J.A.; Navarro, JM; Calleja, JL; Garcia-Samaniego, J; Garcia-Valdecasas, M; Rojas, A; Millan, R; Gonzalez-Escribano, MF; Romero-Gomez, M.

Fine-mapping butyrophilin family genes revealed several polymorphisms influencing viral genotype selection in hepatitis C infection.

GENES AND IMMUNITY, 2015;

FI: 2,913; Q2

Salmeron, J; Vinaixa, C; Berenguer, R; Pascasio, JM; Ruano, JJS; Serra, MA; Gila, A; Diago, M; Romero-Gomez, M; Navarro, JM; Testillano, M; Fernandez, C; Spiny, D; Carmona, I; Pons, J.A.; Jorquera, F; Rodriguez, FJ; Perez, R; Montero, JL; Granados, R; Fernandez, M; Martin, AB; de Rueda, PM; Quiles, R.