Ee19-Toxicology (Emerging)
Epidemiology and Public Health / IBS-Ee19 / Emerging
The group focuses on research in medical, forensic, analytical, clinical, industrial, and food toxicology, ecotoxicology, and toxicity and risk assessment. Among the group's most significant lines of research is the characterization of human exposure to heavy metals and metalloids, with a long history of over 35 years. The group also studies environmental toxins that contribute to the risk of hormone-dependent pathologies such as childhood obesity, neurodevelopmental disorders, and precocious puberty. The influence of environmental toxins on women's health, including the evaluation of the role of molecular markers and genetic susceptibility in the risk of endometriosis and their possible interaction with exposure to environmental toxins (EDs), is another line of research developed by the group.
Clinical analysis researchers specializing in genetics have joined the team. Genetic toxicology allows for the study of possible mechanisms associated with the etiology of various pathologies with both genotoxic and cytotoxic alterations, enabling the development of highly relevant public health strategies. Finally, the Toxicology Unit at the San Cecilio Clinical Hospital in Granada has extensive experience in the analysis of drugs of abuse and other xenobiotics (including EDs) and has state-of-the-art equipment. This aims to promote drug analysis in hair, as well as the determination of other newly discovered addictive substances in biological fluids or tissues.
Research lines
- Characterization of exposure to metals and metalloids in human tissues and biological fluids (urine, blood, saliva, bronchoalveolar fluid, hair, nails, feces, placenta, meconium, organ biopsies, etc.) and their implications for health.
- Characterization of environmental exposure to endocrine disruptors and their implications for maternal, child, and women's health.
- Genetic implications of individual predisposition to xenobiotics and their implications for health.
- Characterization of exposure to drugs of abuse and its determination in fluids and/or hair.
Keywords
Metals; endocrine disruptors; maternal and child health; genetic toxicology; clinical toxicology; toxic risk assessment; drugs of abuse
Cristina Samaniego Sanchez
Lourdes Rodrigo Conde-Salazar
LARA PAPAY RAMIREZ
Pablo Olmedo Palma
FERNANDO GIL HERNANDEZ
FRANCISCO JAVIER GARCIA-VILLANOVA RUIZ
SUSANA GARCIA LINARES
Luis Dominguez Rodriguez
CARMEN FREIRE WARDEN
Association between PFAS exposure and metabolic-related biomarkers in Spanish adolescents
ENVIRONMENTAL RESEARCH, 2025;
FI: 7,7; D1
Associations between chronic exposure to bisphenols and parabens and gut microbiota in children
ENVIRONMENTAL RESEARCH, 2025;
FI: 7,7; D1
Elucidation of xenobiotics in textiles for infants using non-targeted approaches: The role of fabrics as a source of early-life exposure to potentially harmful chemicals
ENVIRONMENTAL RESEARCH, 2025;
FI: 7,7; D1
Elucidation of chemicals of emerging concern in placenta by non-targeted and suspect screening approaches
EMERGING CONTAMINANTS, 2025;
FI: 6,9; Q1
Hair as an Indicator of Prolonged Paraben Exposure and Its Relation to Weight Gain in a Sample of Spanish Children: A Proof-of-Concept Study
NUTRIENTS, 2025;
FI: 5; Q1