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E07-Research in Environmental Health and Children

Epidemiology and Public Health / IBS-E07 / Consolidated

ibs.GRANADA  ·  Research groups
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Group integrated in the CIBER of Epidemiology and Public Health (CIBERESP) dedicated to research in environmental, nutritional and occupational health (biomonitoring of environmental chemical pollutants, exposure to toxins and effects on health), molecular and genetic epidemiology, as well as related aspects with the promotion and protection of children's health.

Research lines

  • The early origin of health and disease (Developmental Origins of Health and Disease (DOHaD)
  • Epi / environmental genetics, reproductive health and child development
  • Human exposure to environmental chemical pollutants, analysis of predictors of exposure and health effects
  • Promotion and protection of children's health

Research networks

  • CIBERESP Networked Biomedical Research Center Epidemiology and Public Health (CB06/02/1021)

Keywords

Persistent and non-persistent chemical pollutants, environmental and molecular epidemiology, endocrine disruptors, reproductive health, child health, health promotion, gene-environment interaction

HELENA GARCIA CORTES

  • ORCID

BEATRIZ GONZALEZ ALZAGA

  • ORCID

ANTONIO FRANCISCO HERNANDEZ JEREZ

  • More Information
  • ORCID

MARINA LACASANA NAVARRO

  • More Information
  • ORCID

IMMACULATE LOPEZ FLORES

DESIRE ROMERO MOLINA

  • More Information
  • ORCID
Lozano-Paniagua, D; Parron, T; Alarcon, R; Requena, M; Lacasaña, M; Hernandez, A.F.

A Th2-type immune response and low-grade systemic inflammatory reaction as potential immunotoxic effects in intensive agriculture farmers exposed to pesticides

SCIENCE OF THE TOTAL ENVIRONMENT, 2024;

FI: 8,2; D1

Navajas-Porras, B; Delgado-Osorio, A; Hinojosa-Nogueira, D; Pastoriza, S; Almécija-Rodríguez, MD; Rufián-Henares, JA; Fernandez-Bayo, JD

Improved nutritional and antioxidant properties of black soldier fly larvae reared on spent coffee grounds and blood meal by-products

FOOD RESEARCH INTERNATIONAL, 2024;

FI: 7; D1

García-Conde, U; Navarro-Moreno, M; Navajas-Porras, B; Hinojosa-Nogueira, D; Delgado-Osorio, A; Pastoriza, S; Moriki, D; Douros, K; Navarro-Alarcón, M; Rufián-Henares, JA

Do cooking techniques influence copper bioaccessibility in foods after in vitro digestion/fermentation in adults and children?

FOOD RESEARCH INTERNATIONAL, 2024;

FI: 7; D1

Hinojosa-Nogueira, D; Russo, MD; Navajas-Porras, B; Delgado-Osorio, A; Pérez-Burillo, S; La Grutta, S; Cilluffo, G; Malizia, V; de la Cueva, SP; Lauria, F; Rufián-Henares, JA

Associations between the prevalence of asthma and dietary exposure to food contaminants in children: CHASER study

WORLD JOURNAL OF PEDIATRICS, 2024;

FI: 3,6; D1

García-Burgos, A; Paraggio, P; Romero-Molina, D; Rico-Castro, N

Inference with Non-Homogeneous Lognormal Diffusion Processes Conditioned on Nearest Neighbor

MATHEMATICS, 2024;

FI: 2,3; D1

Garcia-Conde, U; Navarro-Alarcon, M; Hinojosa-Nogueira, D; Delgado-Osorio, A; Perez-Burillo, S; Pastoriza, S; Navarro-Moreno, M; Rufian-Henares, JA

Total Zn of foods and bioaccessible fractions in the small and large intestine after in vitro digestion and fermentation with fecal material of healthy adults and children: Influence of culinary techniques

FOOD RESEARCH INTERNATIONAL, 2023;

FI: 8,1; D1

Lozano-Paniagua, D; Parron, T; Alarcon, R; Requena, M; Lacasaña, M; Hernandez, A.F.

Renal tubular dysfunction in greenhouse farmers exposed to pesticides unveiled by a panel of molecular biomarkers of kidney injury

ENVIRONMENTAL RESEARCH, 2023;

FI: 8,3; Q1

Bermúdez-Tamayo, C; Mochón, LG; Azarola, AR; Lacasaña, M

Climate change and vector-borne diseases. From knowledge to action

SANITARY GAZETTE, 2023;

FI: 1,9; Q4

Cofiño, R; Prieto, M; Hernán-García, M

Community or barbarism. Community orientation of primary health care at three levels

SANITARY GAZETTE, 2023;

FI: 1,9; Q4

Cardo-Miota, A; Valls-Perez, B; Lineros-Gonzalez, C; Hernan-Garcia, M

Community health. Innovating in the training of family and community medicine residents

SANITARY GAZETTE, 2023;

FI: 1,9; Q4

Karaulov, A.V.; Smolyagin, AI; Mikhailova, IV; Stadnikov, A.A.; Ermolina, EV; Filippova, Y.V. Kuzmicheva, NA; Vlata, Z; Djordjevic, AB; Tsitsimikou, C; Hartung, T; Hernandez, AF; Tsatsakis, A.

Assessment of the combined effects of chromium and benzene on the rat neuroendocrine and immune systems

ENVIRONMENTAL RESEARCH, 2022;

FI: 8,431; D1

Garzarella, EU; Navajas-Porras, B; Perez-Burillo, S; Ullah, H; Esposito, C; Santarcangelo, C; Hinojosa-Nogueira, D; Pastoriza, S; Zaccaria, V; Xiao, J.B. Rufian-Henares, JA; Daglia, M.

Evaluating the effects of a standardized polyphenol mixture extracted from poplar-type propolis on healthy and diseased human gut microbiota

BIOMEDICINE & PHARMACOTHERAPY, 2022;

FI: 7,419; D1

Martin-Way, D; Puche-Sanz, I; Cozar, JM; Zafra-Gomez, A; Gomez-Regalado, MDC; Morales-Alvarez, CM; Hernandez, AF; Martinez-Gonzalez, LJ; Alvarez-Cubero, MJ

Genetic variants of antioxidant enzymes and environmental exposures as molecular biomarkers associated with the risk and aggressiveness of bladder cancer

SCIENCE OF THE TOTAL ENVIRONMENT, 2022;

FI: 10,753; D1

Navajas-Porras, B; Perez-Burillo, S; Hinojosa-Nogueira, D; Pastoriza, S; Rufian-Henares, JA

Relationship of Thermal Treatment and Antioxidant Capacity in Cooked Foods

ANTIOXIDANTS, 2022;

FI: 7,675; D1

Gonzalez-Alzaga, B; Hernandez, AF; Pack, L.K.; Iavicoli, I; Tolonen, H; Santonen, T; Vinceti, M; Filippini, T; Moshammer, H; Probst-Hensch, N; Kolossa-Gehring, M; Lacasana, M

The questionnaire design process in the European Human Biomonitoring Initiative (HBM4EU)

ENVIRONMENT INTERNATIONAL, 2022;

FI: 13,352; D1

Lopez-Maldonado, A; Pastoriza, S; Rufian-Henares, JA

Assessing the antioxidant and metabolic effect of an alpha-lipoic acid and acetyl-L-carnitine nutraceutical

CURRENT RESEARCH IN FOOD SCIENCE, 2021;

Blasco, T.; Perez-Burillo, S; Balzerani, F; Hinojosa-Nogueira, D; Lerma-Aguilera, A; Pastoriza, S; Cendoya, X; Rubio, A; Gosalbes, MJ; Jimenez-Hernandez, N; Francino, M.; Apaolaza, I; Rufian-Henares, JA; Plans, F.J.

An extended reconstruction of human gut microbiota metabolism of dietary compounds

NATURE COMMUNICATIONS, 2021;

FI: 14,919; D1

Perez-Burillo, S; Mill, S; Navajas-Porras, B; Valverde-Moya, AJ; Hinojosa-Nogueira, D; Lopez-Maldonado, A; Pastoriza, S; Rufian-Henares, JA

An in vitro batch fermentation protocol for studying the contribution of food to gut microbiota composition and functionality

NATURE PROTOCOLS, 2021;

FI: 13,491; D1

More, S; Bampidis, V; Benford, D; Bragard, C; Halldorsson, T; Hernandez-Jerez, A; Bennekou, S.H.; Koutsoumanis, K; Machera, K; Naegeli, H; Nielsen, SS; Schlatter, J; Schrenk, D; Silano, V; Turk, D; Younes, M; Arnold, G.; Dorne, JL; Maggiore, A; Pagani, S; S

A systems-based approach to the environmental risk assessment of multiple stressors in honey bees

EFSA JOURNAL, 2021;

FI: 3,336; Q2

Hinojosa-Nogueira, D; Perez-Burillo, S; Garcia-Rincon, I; Rufian-Henares, JA; Pastoriza, S.

A useful and simple tool to evaluate and compare the intake of total dietary polyphenols in different populations

PUBLIC HEALTH NUTRITION, 2021;

FI: 4,022; Q2

Hernandez, AF; Twelve, AO; Goumenou, M; Sarigiannis, D; Aschner, M; Tsatsakis, A

Application of novel technologies and mechanistic data for risk assessment under the real-life risk simulation (RLRS) approach

FOOD AND CHEMICAL TOXICOLOGY, 2020;

FI: 4,679; D1

Perez-Burillo, S; Rajakaruna, S; Pastoriza, S; Paliy, O; Rufian-Henares, J.A.

Bioactivity of food melanoidins is mediated by gut microbiota

FOOD CHEMISTRY, 2020;

FI: 6,306; D1

Henriquez-Hernandez, LA; Romero, D; Gonzalez-Antuna, A; Gonzalez-Alzaga, B; Buzzed, M; Boada, LD; Hernandez, AF; Lopez-Flores, I; Luzardo, OP; Lacasana, M

Biomonitoring of 45 inorganic elements measured in plasma from Spanish subjects: A cross-sectional study in Andalusian population

SCIENCE OF THE TOTAL ENVIRONMENT, 2020;

FI: 6,551; D1

Hinojosa-Nogueira, D; Perez-Burillo, S; Rufian-Henares, J.A.; de la Cueva, SP

Characterization of rums sold in Spain through their absorption spectra, furans, phenolic compounds and total antioxidant capacity.

FOOD CHEMISTRY, 2020;

FI: 6,306; D1

Tsatsakis, A; Petrakis, D; Nikolouzakis, TK; Twelve, AO; Calina, D; Vinceti, M; Goumenou, M; Kostoff, RN; Mamoulakis, C; Aschner, M; Hernandez, AF

COVID-19, an opportunity to reevaluate the correlation between long-term effects of anthropogenic pollutants on viral epidemic / pandemic events and prevalence

FOOD AND CHEMICAL TOXICOLOGY, 2020;

FI: 4,679; D1

Caparros-Gonzalez, RA; Gimenez-Asensio, MJ; Gonzalez-Alzaga, B; Aguilar-Garduno, C; Lorca-Marin, JA; Sheriff, J; Gomez-Becerra, I; Gomez-Ariza, JL; Garcia-Barrera, T; Hernandez, AF; Lopez-Flores, I; Rohlman, DS; Romero-Molina, D; Ruiz-Perez, I; Lacasana, M

Childhood chromium exposure and neuropsychological development in children living in two polluted areas in southern Spain

ENVIRONMENTAL POLLUTION, 2019;

FI: 5,714; D1

Cervera-Mata, A; Navarro-Alarcon, M; Slim, G; Pastoriza, S; Montilla-Gomez, J; Llopis, J; Sanchez-Gonzalez, C; Rufian-Henares, J.A.

Spent coffee grounds Improve the nutritional value in elements of lettuce (Lactuca sativa L.) and are an ecological alternative to inorganic fertilizers

FOOD CHEMISTRY, 2019;

FI: 5,399; D1

Hernandez, AF; Lozano-Paniagua, D; Gonzalez-Alzaga, B; Kavvalakis, MP; Tzatzarakis, MN; Lopez-Flores, I; Aguilar-Garduno, C; Caparros-Gonzalez, RA; Tsatsakis, AM; Lacasana, M.

Biomonitoring of common organophosphate metabolites in hair and urine of children from an agricultural community.

ENVIRONMENT INTERNATIONAL, 2019;

FI: 7,943; D1

Perez-Burillo, S; Mehta, T; Esteban-Munoz, A; Pastoriza, S; Paliy, O; Rufian-Henares, J.A.

Effect of in vitro digestion-fermentation on green and roasted coffee bioactivity: The role of the gut microbiota

FOOD CHEMISTRY, 2019;

FI: 5,399; D1

Perez-Burillo, S; Pastoriza, S; Fernandez-Arteaga, A; Luzon, G; Jimenez-Hernandez, N; D'Auria, G; Francino, MP; Rufian-Henares, JA

Spent Coffee Grounds Extract, Rich in Mannooligosaccharides, Promotes a Healthier Gut Microbial Community in a Dose-Dependent Manner

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2019;

FI: 3,571; D1

Perez-Burillo, S; Rufian-Henares, JA; Pastoriza, S.

Towards an improved global antioxidant response method (GAR plus): Physiological-resembling in vitro digestion-fermentation method

FOOD CHEMISTRY, 2018;

FI: 4,946; D1

Perez-Burillo, S; Rufian-Henares, JA; Pastoriza, S.

Towards an improved Global Antioxidant Response method (GAR plus): Physiological-resembling in vitro antioxidant capacity methods

FOOD CHEMISTRY, 2018;

FI: 4,946; D1

Perez-Burillo, S; Giménez, R; Rufian-Henares, J.A.; Pastoriza, S.

Effect of brewing time and temperature on antioxidant capacity and phenols of white tea: Relationship with sensory properties

FOOD CHEMISTRY, 2018;

FI: 4,946; D1

Perez-Burillo, S; Pastoriza, S; Jimenez-Hernandez, N; D'Auria, G; Francino, MP; Rufian-Henares, JA

Effect of Food Thermal Processing on the Composition of the Gut Microbiota

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2018;

FI: 3,412; D1

Gonzalez-Alzaga, B; Lacasana, M; Hernandez, AF; Arrebola, JP; Lopez-Flores, I; Artacho-Cordon, F; Bonde, J.P.; Olea, N; Aguilar-Garduno, C.

Serum concentrations of organochlorine compounds and predictors of exposure in children living in agricultural communities from South-Eastern Spain

ENVIRONMENTAL POLLUTION, 2018;

FI: 4,358; Q1

Hernandez, AF; Gil, F; Lacasana, M.

Toxicological interactions of pesticide mixtures: an update

ARCHIVES OF TOXICOLOGY, 2017;

FI: 5,901; D1

Hinojosa-Nogueira, D; Walls, J; Rufian-Henares, JA; Pastoriza, S

New Method To Estimate Total Polyphenol Excretion: Comparison of Fast Blue BB versus Folin-Ciocalteu Performance in Urine

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2017;

FI: 3,154; D1

of the Cave, SP; Alvarez, J; Vegvari, A; Montilla-Gomez, J; Cruz-Lopez, O; Delgado-Andrade, C; Rufian-Henares, J.A.

Relationship between HMF intake and SMF formation in vivo: An animal and human study

MOLECULAR NUTRITION & FOOD RESEARCH, 2017;

FI: 4,323; D1

Mustieles, V; Fernandez, M.F.; Martin-Olmedo, P; Gonzalez-Alzaga, B; Fontalba-Navas, A; Hauser, R; Olea, N; Arrebola, JP

Human adipose tissue levels of persistent organic pollutants and metabolic syndrome components: Combining a cross-sectional with a 10-year longitudinal study using a multi-pollutant approach.

ENVIRONMENT INTERNATIONAL, 2017;

FI: 7,088; D1

Panzella, L; Perez-Burillo, S; Pastoriza, S; Martin, MA; Cerruti, P; Goya, L; Ramos, S; Rufian-Henares, JA; Napolitano, A; d'Ischia, M

High Antioxidant Action and Prebiotic Activity of Hydrolyzed Spent Coffee Grounds (HSCG) in a Simulated Digestion-Fermentation Model: Toward the Development of a Novel Food Supplement

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2017;

FI: 3,154; D1

Hernandez, AF; Gonzalez-Alzaga, B; Lopez-Flores, I; Lacasana, M.

Systematic reviews on neurodevelopmental and neurodegenerative disorders linked to pesticide exposure: Methodological features and impact on risk assessment.

ENVIRONMENT INTERNATIONAL, 2016;

FI: 5,929; D1

Rodriguez-Barranco, M; Gil, F; Hernandez, AF; Sheriff, J; Lorca, A; Mendoza, R; Gomez, I; Molina-Villalba, I; Gonzalez-Alzaga, B; Aguilar-Garduno, C; Rohlman, DS; Lacasana, M

Postnatal arsenic exposure and attention impairment in school children

CORTEX, 2016;

FI: 4,314; D1

Jimenez-Zamora, A; Delgado-Andrade, C; Rufian-Henares, J.A.

Antioxidant capacity, total phenols and color profile during the storage of selected plants used for infusion

FOOD CHEMISTRY, 2016;

FI: 4,052; D1

Arches, M.C.; Pastoriza, S; Delgado-Andrade, C; Clement, A; Rufian-Henares, J.A.

Relationship between Glycation and Polyphenol Content and the Bioactivity of Selected Commercial Soy Milks

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2016;

FI: 2,857; D1

Blanco-Munoz, J; Lacasana, M; Lopez-Flores, I; Rodriguez-Barranco, M; Gonzalez-Alzaga, B; Bassol, S; Cebrian, ME; Lopez-Carrillo, L; Aguilar-Garduno, C.

Association between organochlorine pesticide exposure and thyroid hormones in floriculture workers

ENVIRONMENTAL RESEARCH, 2016;

FI: 3,088; Q1

Gonzalez-Alzaga, B; Hernandez, AF; Rodriguez-Barranco, M; Gomez, I; Aguilar-Garduno, C; Lopez-Flores, I; Parron, T; Lacasana, M.

Pre- and postnatal exposures to pesticides and neurodevelopmental effects in children living in agricultural communities from South-Eastern Spain

ENVIRONMENT INTERNATIONAL, 2015;

FI: 5,559; D1

Rojas-Garcia, A; Ruiz-Perez, I; Rodriguez-Barranco, M; Gonçalves Bradley, DC; Pastor-Moreno, G; Ricci-Hair, I

Healthcare interventions for depression in low socioeconomic status populations: A systematic review and meta-analysis

CLINICAL PSYCHOLOGY REVIEW, 2015;

FI: 6,932; D1

Pastoriza, S; Rufian-Henares, J.A.; Delgado-Andrade, C.

Effects of long-term consumption of standard diets including glucose-lysine model glycated compounds on the antioxidant status of adult rats.

FOOD CHEMISTRY, 2015;

FI: 3,391; D1

Gomez-Martin, A; Hernandez, AF; Martinez-Gonzalez, LJ; Gonzalez-Alzaga, B; Rodriguez-Barranco, M; Lopez-Flores, I; Aguilar-Garduno, C; Lacasana, M.

Polymorphisms of pesticide-metabolizing genes in children living in intensive farming communities.

CHEMOSPHERE, 2015;

FI: 3,34; Q1

Walls, JJ; Zabala, M; Oliveras-Lopez, MJ; Bouzas, PR; Knox, E; Rufian-Henares, JA; de la Serrana, HLG

Effect of Physical Activity, Nutritional Education, and Consumption of Extra Virgin Olive Oil on Lipid, Physiological, and Anthropometric Profiles in a Pediatric Population

JOURNAL OF PHYSICAL ACTIVITY & HEALTH, 2015;

FI: 2,09; Q1

Effect of pre- and postnatal exposure to glyphosate and AMPA on childhood neuropsychological development: mediating effect of biomarkers of neurological damage and thyroid profile.

Funder: CARLOS III HEALTH INSTITUTE - FEDER

File number: PI23 / 01389

Execution time: 01/01/2024 - 31/12/2026

PI: BEATRIZ GONZALEZ ALZAGA

Effect of prenatal exposure to mixtures of organophosphate compounds on the expression and methylation of placental genes involved in fetal growth and infant neurodevelopment.

Funder: FUNDACION PUBLICA ANDALUZA PROGRESO Y SALUD

File number: FPS-0199-2021

Execution time: 23/03/2022 - 23/03/2025

PI: MARINA LACASAÑA NAVARRO

PARC – Partnership for the Assessment of Risks from Chemicals

Funder: EUROPEAN COMMISSION

File number: 101057014

Execution time: 01/05/2022 - 01/06/2029

PI: MARINA LACASAÑA NAVARRO

PI-0405-2014 - Effect of Maternal Intake of Methyl Group Donor Nutrients on Placenta DNA Methylation and Fetal Growth

Funder: FUNDACION PUBLICA ANDALUZA PROGRESO Y SALUD

File number: PI-0405-2014

Execution time: 01/08/2015 - 31/07/2017

PI: INMACULADA LOPEZ FLORES

Interaction Between Exposure To Organophosphate Pesticides and Mother's Psychological Stress During Pregnancy on Cortisol Levels, Fetal Growth and Infant Neurodevelopment.

Funder: COUNCIL OF HEALTH

File number: PS-0205-2016

Execution time: 01/01/2017 - 31/12/2018

PI: MARINA LACASAÑA NAVARRO

Maternal metabolomic profile of fetal growth and its association with exposure to organophosphate pesticides

Funder: CARLOS III HEALTH INSTITUTE - FEDER

File number: PI17 / 01650

Execution time: 01/01/2018 - 31/12/2020

PI: INMACULADA LOPEZ FLORES

Prenatal and postnatal exposure to organophosphate flame retardants and neurodevelopment at 12 and 24 months of age.

Funder: CARLOS III HEALTH INSTITUTE - FEDER

File number: PI17 / 00638

Execution time: 01/01/2018 - 31/12/2020

PI: MARINA LACASAÑA NAVARRO

European Human Biomonitoring Initiative (EHBMI)

Funder: EUROPEAN COMMISSION

File number: 733032

Execution time: 01/01/2017 - 31/12/2021

PI: MARINA LACASAÑA NAVARRO

Prospective study of the effects of prenatal exposure to metal mixtures on infant neurodevelopment at the ages of 1, 2 and 4 years

Funder: COUNCIL OF HEALTH AND FAMILIES

File number: PI-0243-2019

Execution time: 01/01/2020 - 31/12/2022

PI: BEATRIZ GONZALEZ ALZAGA

STANCE4HEALTH - Smart Technologies for personAlised Nutrition and Consumer Engagement

Funder: EUROPEAN COMMISSION

File number: 816303

Execution time: 01/10/2018 - 30/09/2022

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Responsible researcher

MARINA LACASANA NAVARRO

  • marina.lacasana.easp@juntadeandalucia.es
  • More Information
  • ORCID

Responsible Co-Investigator

ANTONIO FRANCISCO HERNANDEZ JEREZ

  • ajerez@ugr.es
  • More Information
  • ORCID

Research

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