A15-Basic and Clinical Oncology
Oncology / IBS-A15 / Consolidated
It is a multidisciplinary group made up of clinical doctors, physiotherapists, biologists, chemists and environmentalists who join forces in the study of the environmental causes of common diseases and in the diagnosis and treatment of tumor diseases. Participation in the CIBER of Epidemiology and Public Health, (Area of Labor and Environmental Epidemiology), the Childhood and Environment Network (INMA), the European Network for Biomonitoring of Environmental Exposure (HBM4EU), the Biobank Platform and collaboration in the studies MCC-Spain, EPIC-Spain and Project of Excellence of the ibs.Granada (JA Marchal), provide guidance on the objectives of the group.
Research lines
- Radiological diagnosis
- Environmental epidemiology
- Risk factors in chronic diseases
- Personalized medicine
- Tumor radiobiology
- Cancer treatments
Research networks
- CIBERESP - Network Biomedical Research Center Epidemiology and Public Health
MIGUEL MARISCAL ARCAS
LETICIA HERAS GONZALEZ
LYDIA ESPIN MORENO
ELENA SALAMANCA FERNANDEZ
BEATRIZ SUAREZ GONZALEZ
ALICIA OLIVAS MARTINEZ
PABLO TORNE POYATOS
FERNANDO VELA SORIA
MERCEDES VILLALOBOS TORRES
MARIANA FATIMA FERNANDEZ CABRERA
LUZ MARIA IRIBARNE DURAN
JOSE LUIS MARTIN RODRIGUEZ
VICENTE MUSTIELES MIRALLES
MARIA ISABEL NUÑEZ TORRES
NICOLAS OLEA SERRANO
MARIA POVEDANO JIMENEZ
IRIS REINA PEREZ
ANDREA RODRIGUEZ CARRILLO
MANUEL ARANDA HARO
FRANCISCO ARTACHO CORDON
DIEGO BECERRA GARCIA
Placental concentrations of xenoestrogenic organochlorine pesticides and polychlorinated biphenyls and assessment of their xenoestrogenicity in the PA-MAMI mother-child cohort
ENVIRONMENTAL RESEARCH, 2024;
FI: 7,7; D1
Placental concentrations of xenoestrogenic organochlorine pesticides and polychlorinated biphenyls and assessment of their xenoestrogenicity in the PA-MAMI mother-child cohort
ENVIRONMENTAL RESEARCH, 2024;
FI: 7,7; D1
Urinary concentrations of bisphenol A, parabens and benzophenone-type ultra violet light filters in relation to sperm DNA fragmentation in young men: A chemical mixtures approach
SCIENCE OF THE TOTAL ENVIRONMENT, 2024;
FI: 8,2; D1
Urinary concentrations of bisphenol A, parabens and benzophenone-type ultra violet light filters in relation to sperm DNA fragmentation in young men: A chemical mixtures approach
SCIENCE OF THE TOTAL ENVIRONMENT, 2024;
FI: 8,2; D1
Associations between synthetic phenols, phthalates, and placental growth/function: a longitudinal cohort with exposure assessment in early pregnancy
HUMAN REPRODUCTION OPEN, 2024;
FI: 8,3; D1
Expression Profiles of Genes Related to Development and Progression of Endometriosis and Their Association with Paraben and Benzophenone Exposure
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023;
FI: 5,6; Q1
Longitudinal Associations between Prenatal Exposure to Phthalates and Steroid Hormones in Maternal Hair Samples from the SEPAGES Cohort
ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2023;
FI: 11,4; Q1
Effect of a Multimodal Supervised Therapeutic Exercise Program on Quality of Life, Pain, and Lumbopelvic Impairments in Women With Endometriosis Unresponsive to Conventional Therapy: A Randomized Controlled Trial
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION, 2023;
FI: 4,3; Q1
The Effects of Melatonin Supplementation on Professional Football Player Performance: A Systematic Review
NUTRIENTS, 2023;
FI: 5,9; Q1
Cognitive Performance and Exposure to Organophosphate Flame Retardants in Children: Evidence from a Cross-Sectional Analysis of Two European Mother-Child Cohorts
TOXICS, 2023;
FI: 4,6; Q2
Association between serum per- and polyfluoroalkyl substances concentrations and common cold among children and adolescents in the United States
ENVIRONMENT INTERNATIONAL, 2022;
FI: 13,352; D1
Association of blood trihalomethane concentrations with asthma in US adolescents: nationally representative cross-sectional study
EUROPEAN RESPIRATORY JOURNAL, 2022;
FI: 33,795; D1
Association of prenatal phthalate exposure with pubertal development in Spanish boys and girls
ENVIRONMENTAL RESEARCH, 2022;
FI: 8,431; D1
BDNF as a potential mediator between childhood BPA exposure and behavioral function in adolescent boys from the INMA-Granada cohort
SCIENCE OF THE TOTAL ENVIRONMENT, 2022;
FI: 10,753; D1
Biomonitoring bisphenols, parabens, and benzophenones in breast milk from a human milk bank in Southern Spain
SCIENCE OF THE TOTAL ENVIRONMENT, 2022;
FI: 10,753; D1
Adipose Tissue Redox Microenvironment as a Potential Link between Persistent Organic Pollutants and the 16-Year Incidence of Non-hormone-Dependent Cancer..
ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2021;
FI: 9,028; D1
Adipose tissue cadmium concentrations as a potential risk factor for insulin resistance and future type 2 diabetes mellitus in GraMo adult cohort.
SCIENCE OF THE TOTAL ENVIRONMENT, 2021;
FI: 7,963; D1
A human biomonitoring (HBM) Global Registry Framework: Further advancement of HBM research following the FAIR principles
INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH, 2021;
FI: 5,84; Q1
Assessment of perfluoroalkyl substances in placenta by coupling salt assisted liquid-liquid extraction with dispersive liquid-liquid microextraction prior to liquid chromatography-tandem mass spectrometry
TALANTA, 2021;
FI: 6,057; Q1
Assessment of chemical mixtures using biomarkers of combined biological activity: A screening study in human placentas
REPRODUCTIVE TOXICOLOGY, 2021;
FI: 3,143; Q3
Adipose tissue concentrations of arsenic, nickel, lead, tin, and titanium in adults from GraMo cohort in Southern Spain: An exploratory study
SCIENCE OF THE TOTAL ENVIRONMENT, 2020;
FI: 6,551; D1
Association of placental concentrations of phenolic endocrine disrupting chemicals with cognitive functioning in preschool children from the Environment and Childhood (INMA) Project.
INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH, 2020;
FI: 4,801; D1
Matrix metalloproteases and TIMPs as prognostic biomarkers in breast cancer patients treated with radiotherapy: A pilot study
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 2020;
FI: 4,658; Q1
Association of Parental Preconception Exposure to Phthalates and Phthalate Substitutes With Preterm Birth
JAMA NETWORK OPEN, 2020;
FI: 5,032; Q1
An on-lattice agent-based Monte Carlo model simulating the growth kinetics of multicellular tumor spheroids.
PHYSICA MEDICA-EUROPEAN JOURNAL OF MEDICAL PHYSICS, 2020;
FI: 2,485; Q2
Adipose tissue concentrations of non-persistent environmental phenols and local redox balance in adults from Southern Spain
ENVIRONMENT INTERNATIONAL, 2019;
FI: 7,943; D1
Concentrations of bisphenol A and parabens in socks for infants and young children in Spain and their hormone-like activities
ENVIRONMENT INTERNATIONAL, 2019;
FI: 7,943; D1
Presence of Bisphenol A and Parabens in a Neonatal Intensive Care Unit: An Exploratory Study of Potential Sources of Exposure
ENVIRONMENTAL HEALTH PERSPECTIVES, 2019;
FI: 7,736; D1
Contribution of sociodemographic, occupational, lifestyle and dietary characteristics to the oxidative stress microenvironment in adipose tissue.
ENVIRONMENTAL RESEARCH, 2019;
FI: 5,026; D1
Determination of bisphenol A and bisphenol S concentrations and assessment of estrogen- and anti-androgen-like activities in thermal paper receipts from Brazil, France, and Spain
ENVIRONMENTAL RESEARCH, 2019;
FI: 5,026; D1
Environmental phenols and parabens in adipose tissue from hospitalized adults in Southern Spain
ENVIRONMENT INTERNATIONAL, 2018;
FI: 7,297; D1
Preconception and prenatal urinary concentrations of phenols and birth size of singleton infants born to mothers and fathers from the Environment and Reproductive Health (EARTH) study
ENVIRONMENT INTERNATIONAL, 2018;
FI: 7,297; D1
Spatial and temporal variability of personal environmental exposure to radio frequency electromagnetic fields in children in Europe
ENVIRONMENT INTERNATIONAL, 2018;
FI: 7,297; D1
Personal exposure to radio-frequency electromagnetic fields in Europe: Is there a generation gap?
ENVIRONMENT INTERNATIONAL, 2018;
FI: 7,297; D1
Urinary bisphenol A concentrations are associated with reproductive parameters in young men
ENVIRONMENTAL RESEARCH, 2018;
FI: 4,732; D1
Human adipose tissue levels of persistent organic pollutants and metabolic syndrome components: Combining a cross-sectional with a 10-year longitudinal study using a multi-pollutant approach.
ENVIRONMENT INTERNATIONAL, 2017;
FI: 7,088; D1
Serum levels of organochlorine pesticides in blood donors: A biomonitoring survey in the North of Brazil, 2010-2011
SCIENCE OF THE TOTAL ENVIRONMENT, 2017;
FI: 4,9; D1
The Influence of Meteorological Factors and Atmospheric Pollutants on the Risk of Preterm Birth
AMERICAN JOURNAL OF EPIDEMIOLOGY, 2017;
FI: 4,825; D1
Paternal and maternal urinary phthalate metabolite concentrations and birth weight of singletons conceived by subfertile couples.
ENVIRONMENT INTERNATIONAL, 2017;
FI: 7,088; D1
Ultrasound gel as an unrecognized source of exposure to phthalates and phenols among pregnant women undergoing routine scan
INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH, 2017;
FI: 4,643; D1
Contribution of Persistent Organic Pollutant Exposure to the Adipose Tissue Oxidative Microenvironment in an Adult Cohort: A Multipollutant Approach
ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2016;
FI: 5,393; D1
Total Effective Xenoestrogen Burden in Serum Samples and Risk for Breast Cancer in a Population-Based Multicase-Control Study in Spain
ENVIRONMENTAL HEALTH PERSPECTIVES, 2016;
FI: 8,443; D1
Occupational Exposure to Endocrine-Disrupting Chemicals and Birth Weight and Length of Gestation: A European Meta-Analysis
ENVIRONMENTAL HEALTH PERSPECTIVES, 2016;
FI: 8,443; D1
Total Effective Xenoestrogen Burden in Serum Samples and Risk for Breast Cancer in a Population-Based Multicase-Control Study in Spain
ENVIRONMENTAL HEALTH PERSPECTIVES, 2016;
FI: 8,443; D1
Prenatal Ambient Air Pollution, Placental Mitochondrial DNA Content, and Birth Weight in the INMA (Spain) and ENVIRONAGE (Belgium) Birth Cohorts
ENVIRONMENTAL HEALTH PERSPECTIVES, 2016;
FI: 8,443; D1
Analytical methods for the assessment of endocrine disrupting chemical exposure during human fetal and lactation stages: A review
CHEMICAL ANALYTICS ACTA, 2015;
FI: 4,513; D1
Historical exposure to persistent organic pollutants and risk of incident hypertension
ENVIRONMENTAL RESEARCH, 2015;
FI: 4,373; D1
Levels and predictors of persistent organic pollutants in an adult population from four Spanish regions
SCIENCE OF THE TOTAL ENVIRONMENT, 2015;
FI: 4,099; D1
Outdoor characterization of radio frequency electromagnetic fields in a Spanish birth cohort
ENVIRONMENTAL RESEARCH, 2015;
FI: 4,373; D1
Relationship between serum concentrations of persistent organic pollutants and markers of insulin resistance in a cohort of women with a history of gestational diabetes mellitus.
ENVIRONMENTAL RESEARCH, 2015;
FI: 4,373; D1
Novel non-invasive test to early detect endometrial cancer based on genomic exploitation and microscopy imaging of urine samples
Funder: BIOMEDICAL RESEARCH CENTER IN EPIDEMIOLOGY AND PUBLIC HEALTH NETWORK
File number: ESP23PI05
Execution time: 27/02/2023 - 31/12/2024
IP: ELENA SALAMANCA FERNANDEZ
Endometriosis and Pollution
Funder: BIOMEDICAL RESEARCH CENTER IN EPIDEMIOLOGY AND PUBLIC HEALTH NETWORK
File number: ESP23PI04
Execution time: 27/02/2023 - 31/12/2024
IP: CARMEN FREIRE WARDEN
Human exposure to mixtures of environmental chemicals: Predicting and mitigating health effects using new molecular and radiological biomarkers
Funder: CARLOS III HEALTH INSTITUTE - FEDER
File number: PI23 / 01884
Execution time: 01/01/2024 - 31/12/2026
IP: VICENTE MUSTIELES MIRALLES
PARC – Partnership for the Assessment of Risks from Chemicals.
Funder: EUROPEAN COMMISSION
File number: 101057014
Execution time: 01/05/2022 - 01/06/2029
PI: MARIANA FATIMA FERNANDEZ CABRERA
ELEMENTUM: Early-Life Exposure to a Mixture of Endocrine disruptors, Neurodevelopmental Trajectories and new insights on Underlying Mechanisms
Funder: FONDATION DE FRANCE
File number: ELEMENTUM
Execution time: 04/01/2022 - 03/01/2025
IP: VICENTE MUSTIELES MIRALLES
Influence of exposure to non-persistent endocrine disruptors on the development of early simple thelarche
Funder: CARLOS III HEALTH INSTITUTE - FEDER
File number: PI20 / 01656
Execution time: 01/01/2021 - 31/12/2023
IP: CARMEN FREIRE WARDEN
Development of a Procedure for Minimizing the Presence of Antineoplastic Drugs of Hospital Origin
Funder: COUNCIL OF HEALTH
File number: PS-0506-2016
Execution time: 01/01/2017 - 31/12/2019
PI: Development of a Procedure to Minimize the Presence of Antineoplastic Drugs of Hospital Origin
Very low birth weight newborn exposure to endocrine disruptors (EDs) in the Neonatal Care Unit (NICU) and evaluation of the consequences on development.
Funder: CARLOS III HEALTH INSTITUTE - FEDER
File number: PI16 / 01820
Execution time: 01/01/2017 - 31/12/2019
PI: NICOLAS OLEA SERRANO
ONCONET SUDOE - Réseau Européen de Recherche translationnelle et d'Innovation en oncologie
Funder: EUROPEAN COMMISSION
File number: SOE1-P1-F0082-2015
Execution time: 01/07/2016 - 30/06/2019
PI: NICOLAS OLEA SERRANO
Exposure to non-persistent endocrine-disrupting pesticides and reproductive function among adolescent boys: a cross-sectional study in the INMA-Granada cohort
Funder: CARLOS III HEALTH INSTITUTE - FEDER
File number: CP16 / 00085-P
Execution time: 01/01/2017 - 31/12/2019
IP: CARMEN FREIRE WARDEN
Total effective obesogenic load: a new biomarker with a combined effect of obesogens as a risk factor in obesity
Funder: CARLOS III HEALTH INSTITUTE - FEDER
File number: PI16 / 01812
Execution time: 01/01/2017 - 31/12/2019
PI: MARIANA FATIMA FERNANDEZ CABRERA
Contribution of human exposure to endocrine disruptors in the genesis and development of endometriosis in women of childbearing age.
Funder: CARLOS III HEALTH INSTITUTE - FEDER
File number: PI17 / 01743
Execution time: 01/01/2018 - 31/12/2020
IP: FRANCISCO ARTACHO CORDON
Exposure to non-persistent pesticides, time of puberty and genetic susceptibility in children and adolescents: INMA-Ado-PubPest Project
Funder: CARLOS III HEALTH INSTITUTE - FEDER
File number: PI17 / 01526
Execution time: 01/01/2018 - 31/12/2020
IP: CARMEN FREIRE WARDEN
Endocrine disruptors, microbiota, and breast cancer
Funder: UNIVERSITY OF GRANADA
File number: B-CTS-254-UGR18
Execution time: 01/01/2020 - 31/12/2021
PI: MARIANA FATIMA FERNANDEZ CABRERA
Evaluation of Incidental Cardiac Uptake in Bone Scintigraphy – ECCINGO Study
Funder: PFIZER, SLU
Type of test: COMMERCIAL POST AUTHORIZATION STUDY
Execution time: 07/05/2021 - 07/05/2022
IP: DIEGO BECERRA GARCIA
Phase III, randomized, double-blind clinical trial of neoadjuvant chemotherapy with atezolizumab or placebo in patients with triple negative breast cancer, followed by adjuvant atezolizumab or placebo. (GEPARDOUZE)
Funder: GERMAN BREAST GBG FORSCHUNGSGESELLSCHAFT GMBH
Type of test: COMMERCIAL CLINICAL TRIAL
Execution time: 23/07/2020 - 30/09/2024
IP: ISABEL BLANCAS LOPEZ-BARAJAS
Observational study in patients with HR + and Her2- metastatic breast cancer treated with abemaciclib in the NPU (Compassionate Use Program) program in Spain. ABEMUSS study. 2018-8023
Financier: LILLY, SA
Type of test: COMMERCIAL POST AUTHORIZATION STUDY
Execution time: 18/04/2020 - 30/06/2020
IP: ISABEL BLANCAS LOPEZ-BARAJAS
Ambispective observational study of pregnancy and breast cancer registry. EMBARCAM
Funder: FUNDACION GRUPO ESPAÑOL DE INVESTIGACIÓN EN CANCER MAMA
Type of test: INDEPENDENT POST-AUTHORIZATION STUDY
Execution time: 17/02/2020 - 17/02/2024
IP: ISABEL BLANCAS LOPEZ-BARAJAS
Retrospective registry of patients with HR + Her2-treated locally advanced / metastatic breast cancer in clinical practice in Andalusia.
Funder: SOCIEDAD ANDALUZA DE ONCOLOGIA MEDICA
Type of test: INDEPENDENT POST-AUTHORIZATION STUDY
Execution time: 06/10/2020 - 30/07/2021
IP: ISABEL BLANCAS LOPEZ-BARAJAS
Neratinib therapy targeting EGFR / ERBB2 receptors in hormone receptor-positive / HER2-negative and HER2-enriched metastatic breast cancer
Funder: SOLTI
Type of test: INDEPENDENT CLINICAL TRIAL
Execution time: 30/06/2020 - 30/06/2024
IP: ISABEL BLANCAS LOPEZ-BARAJAS
Multicenter, randomized, open-label phase II study with two neoadjuvant treatment arms to evaluate the efficacy, safety and pharmacokinetics of GDC-9545 plus palbociclib compared to anastrozole plus palbociclib in postmenopausal women with cann
Financier: ROCHE FARMA, SA
Type of test: COMMERCIAL CLINICAL TRIAL
Execution time: 16/11/2020 - 28/02/2022
IP: ISABEL BLANCAS LOPEZ-BARAJAS
