A09-Genetics and Molecular Oncology
Oncology / IBS-A09 / Consolidated
Group A-09 of the Biosanitary Research Institute of Granada is focused on molecular oncology, in the study of molecular bases and gene expression profiles in cancer. In our group we intend the genetic study of tumors, specifically we are focused on lung cancer. Understanding the genetic characteristics and biology of the tumor is important because it can allow finding altered genes and altered proteins in specific tumor types that can be used as biomarkers and targets for the development of new therapies that cancer patients can benefit from. lung. On the other hand, the research group is also focused on the study of new pharmacological compounds with antitumor activity directed against new therapeutic targets.
Keywords
Non-small cell lung cancer; Adenocarcinoma; Squamous lung cancer; Biomarkers; Therapeutic targets; Anti-tumor drugs.
CLAUDIA TESO PEREZ
MANUEL MARTINEZ GOOD
MARIA ESTHER FAREZ VIDAL
MARIA AMELIA GOMEZ LLORENTE
ABEL SANCHEZ-PALENCIA RAMOS
Biomimetic magnetic nanoparticles for bacterial magnetic concentration in liquids and qPCR-detection
FOOD CONTROL, 2023;
FI: 6; Q1
Lactiplantibacillus paraplantarum BPF2 and Pediococcus acidilactici ST6, Two Bacteriocinogenic Isolated Strains from Andalusian Spontaneous Fermented Sausages
FOODS, 2023;
FI: 5,2; Q1
Advances in the preclinical characterization of the antimicrobial peptide AS-48
FRONTIERS IN MICROBIOLOGY, 2023;
FI: 5,2; Q2
Circular and L50-like leaderless enterocins share a common ABC-transporter immunity gene
BMC GENOMICS, 2023;
FI: 4,4; Q2
Allium-Derived Compound Propyl Propane Thiosulfonate (PTSO) Reduces Vibrio Populations and Increases Body Weight of European Seabass (Dicentrarchus labrax) Juveniles
ANTIBIOTICS-BASEL, 2023;
FI: 4,8; Q2
PKP1 and MYC create a feedforward loop linking transcription and translation in squamous cell lung cancer.
CELLULAR ONCOLOGY, 2022;
FI: 7,051; Q1
Intrinsically disordered protein NUPR1 binds to the armadillo-repeat domain of Plakophilin 1
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECLES, 2021;
FI: 6,953; D1
Enterocin Cross-Resistance Mediated by ABC Transport Systems
MICROORGANISMS, 2021;
FI: 4,128; Q2
The armadillo-repeat domain of plakophilin 1 binds the C-terminal sterile alpha motif (SAM) of p73
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 2021;
FI: 3,77; Q2
Plakophilin 1 enhances MYC translation, promoting squamous cell lung cancer
ONCOGENE, 2020;
FI: 7,971; D1
A Multi-Omics Approach Reveals New Signatures in Obese Allergic Asthmatic Children
BIOMEDICINE, 2020;
FI: 4,717; Q1
The isolated armadillo-repeat domain of Plakophilin 1 is a monomer in solution with a low conformational stability
JOURNAL OF STRUCTURAL BIOLOGY, 2020;
FI: 3,071; Q2
The value of desmosomal plaque-related markers to distinguish squamous cell carcinoma and adenocarcinoma of the lung
UPSALA JOURNAL OF MEDICAL SCIENCES, 2020;
FI: 1,955; Q2
Expression of the long non-coding RNA TCL6 is associated with clinical outcome in pediatric B-cell acute lymphoblastic leukemia
BLOOD CANCER JOURNAL, 2019;
FI: 7,895; D1
BRG1 regulation by miR-155 in human leukemia and lymphoma cell lines (vol 19, pg 1010, 2017)
CLINICAL & TRANSLATIONAL ONCOLOGY, 2019;
FI: 2,441; Q3
HLA class I loss and PD-L1 expression in lung cancer: impact on T-cell infiltration and immune escape
ONCOTARGET, 2018;
Predictors for 30-day readmission after pulmonary resection for lung cancer
JOURNAL OF SURGICAL ONCOLOGY, 2018;
FI: 2,886; Q1
The absence of HLA class I expression in non-small cell lung cancer correlates with the tumor tissue structure and the pattern of T cell infiltration.
INTERNATIONAL JOURNAL OF CANCER, 2017;
FI: 6,513; Q1
Preoperative chemoradiotherapy for rectal cancer: the sensitizer role of the association between miR-375 and c-Myc
ONCOTARGET, 2017;
FI: 5,168; Q1
Obesity and Asthma: A Missing Link
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2017;
FI: 3,226; Q2
BRG1 regulation by miR-155 in human leukemia and lymphoma cell lines
CLINICAL & TRANSLATIONAL ONCOLOGY, 2017;
FI: 2,353; Q3
Impact of major video-assisted thoracoscopic surgery on care quality
JOURNAL OF THORACIC DISEASE, 2017;
FI: 2,365; Q3
Progressive changes in composition of lymphocytes in lung tissues from patients with non-small-cell lung cancer.
ONCOTARGET, 2016;
FI: 5,008; Q1
Periodontopathogen and Epstein-Barr virus-associated periapical periodontitis may be the source of retrograde infectious peri-implantitis.
CLINICAL IMPLANT DENTISTRY AND RELATED RESEARCH, 2015;
FI: 3,589; D1
Expression inactivation of SMARCA4 by microRNAs in lung tumors.
HUMAN MOLECULAR GENETICS, 2015;
FI: 6,393; D1
Quantitative-fluorescent-PCR versus full karyotyping in prenatal diagnosis of common chromosome aneuploidies in southern Spain.
CLINICAL CHEMISTRY AND LABORATORY MEDICINE, 2015;
FI: 2,707; Q1
Observational, prospective, European, multicenter, mixed methods study to describe the lived experience of X-linked hypophosphatemia (XLH) for adolescents at the end of skeletal growth
Funder: KIOWA KIRIN INTERNATIONAL
Type of test: OBSERVATIONAL STUDY WITH MEDICATION
Execution time: 13/06/2022 - 30/06/2023
IP: MARIA AMELIA GOMEZ LLORENTE