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Internal expression of interest ISCIII-CDTI Joint Action on Personalized Medicine and Advanced Therapies 2023


    (maximum one page indicating IP, group, thematic area, strategic lines, brief summary of the project, type of participation and autonomous communities that will participate in the project)


    Development of technological platforms, medical imaging, biomarkers and medical devices that allow early diagnosis and clinical and scientific monitoring of people at home, with special attention to the identification of frailty, cognitive deterioration, early diagnosis of diseases related to aging, exacerbation of chronic diseases and control of adverse drug effectsDevelopment and clinical validation of medical devices aimed at reducing health risks in frail elderly people or at risk of frailty and their integration into personalized precision medicine systemsDevelopment and clinical validation of health technology for casual screening, non-specialized management, for use in non-conventional health spaces and its subsequent integration into conventional care processes to respond to unmet clinical needs in frail elderly people or at risk of frailty, in association with developments related to personalized precision medicineDevelopment and clinical validation in the National Health System of technology aimed at home health care for people with high dependency or extreme old age, and its integration with personalized precision medicine systemsDevelopment and full regulatory validation of biomarkers for chronic and oncological diseases, which combine the possibility of being detectable by non-invasive imaging techniques or in easily accessible organic fluids or tissues and the characteristic of being linked to a pharmacologically actionable molecular targetValidation of frailty biomarkers, for diagnostic, therapeutic, rehabilitation or monitoring purposes, in large population samples or in complementary cohortsResearch and development of advanced therapy drugs aimed at elderly patients with chronic and oncological diseases, or frail populations or those at risk of frailtyInnovative tools aimed at improving the precision or simplification of surgical techniques in this populationHealth technology aimed at the early rehabilitation of elderly patients with chronic diseases or frail people or people at risk of frailty, with a precision medicine perspective

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